Calpain inhibitor II induces caspase-dependent apoptosis in human acute lymphoblastic leukemia and non-Hodgkin's lymphoma cells as well as some solid tumor cells.
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[1] Robert W. Schrier,et al. The role of the calcium-dependent enzymes nitric oxide synthase and calpain in hypoxia-induced proximal tubule injury. , 1996, Renal failure.
[2] T. Watanabe,et al. Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice , 1996, The Journal of experimental medicine.
[3] B. Pettmann,et al. Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis. , 1998, Journal of cell science.
[4] G. Demartino,et al. Calcium-activated neutral protease (calpain) system: structure, function, and regulation. , 1991, Physiological reviews.
[5] S. Orrenius,et al. CPP32/Apopain Is a Key Interleukin 1 Converting Enzyme-like Protease Involved in Fas-mediated Apoptosis (*) , 1996, The Journal of Biological Chemistry.
[6] Xiaodong Wang,et al. Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 , 1997, Cell.
[7] M. Gnegy,et al. Calcium/Calmodulin-dependent Protein Kinase IV Is Cleaved by Caspase-3 and Calpain in SH-SY5Y Human Neuroblastoma Cells Undergoing Apoptosis* , 1998, The Journal of Biological Chemistry.
[8] R. Miller,et al. Role of calpain- and interleukin-1 beta converting enzyme-like proteases in the beta-amyloid-induced death of rat hippocampal neurons in culture. , 1997, Journal of neurochemistry.
[9] J. Bolen,et al. Membrane-associated CD19-LYN complex is an endogenous p53-independent and Bc1-2-independent regulator of apoptosis in human B-lineage lymphoma cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[10] K. Suzuki,et al. Structure and physiological function of calpains. , 1997, The Biochemical journal.
[11] M. Molinari,et al. Calpain: a protease in search of a function? , 1998, Biochemical and biophysical research communications.
[12] S. Srinivasula,et al. Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade , 1997, Cell.
[13] K. Raser,et al. Effects of ICE‐like protease and calpain inhibitors on neuronal apoptosis , 1996, Neuroreport.
[14] A. Burkhardt,et al. Biotherapy of B-cell precursor leukemia by targeting genistein to CD19-associated tyrosine kinases , 1995, Science.
[15] K. Wang,et al. Development and therapeutic potential of calpain inhibitors. , 1997, Advances in pharmacology.
[16] A. Malkinson,et al. Calpain activation in apoptosis , 1994, Journal of cellular physiology.
[17] F. Uckun,et al. Calphostin C triggers calcium-dependent apoptosis in human acute lymphoblastic leukemia cells. , 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.
[18] R. Gilbertsen,et al. Non-erythroid alpha-spectrin breakdown by calpain and interleukin 1 beta-converting-enzyme-like protease(s) in apoptotic cells: contributory roles of both protease families in neuronal apoptosis. , 1996, The Biochemical journal.
[19] Fatih M. Uckun,et al. Bruton’s Tyrosine Kinase as an Inhibitor of the Fas/CD95 Death-inducing Signaling Complex* , 1999, The Journal of Biological Chemistry.
[20] F. Uckun,et al. A requirement for protein kinase C inhibition for calcium-triggered apoptosis in acute lymphoblastic leukemia cells. , 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.
[21] J. Cohen,et al. Calpain, an upstream regulator of thymocyte apoptosis. , 1997, Journal of immunology.
[22] M. Clerici,et al. Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors. , 1994, Journal of immunology.
[23] P. Henkart. ICE family proteases: mediators of all apoptotic cell death? , 1996, Immunity.
[24] T. Kurosaki,et al. BTK as a Mediator of Radiation-Induced Apoptosis in DT-40 Lymphoma B Cells , 1996, Science.
[25] A. Gressner,et al. Attenuation of TGF-beta-induced apoptosis in primary cultures of hepatocytes by calpain inhibitors. , 1997, Biochemical and biophysical research communications.
[26] Y. Lazebnik,et al. Caspases: enemies within. , 1998, Science.
[27] B. Mignotte,et al. Mitochondria and apoptosis. , 1998, European journal of biochemistry.
[28] N. Thornberry,et al. Inhibition of Human Caspases by Peptide-based and Macromolecular Inhibitors* , 1998, The Journal of Biological Chemistry.
[29] K. Wang,et al. Calpain inhibition: an overview of its therapeutic potential. , 1994, Trends in pharmacological sciences.