Anastomotic leak in colorectal cancer patients: New insights and perspectives.

[1]  R. Kawabata,et al.  Prognostic impact of postoperative intra-abdominal infections after elective colorectal cancer resection on survival and local recurrence: a propensity score-matched analysis , 2020, International Journal of Colorectal Disease.

[2]  A. Zaborin,et al.  Prevention of Anastomotic Leak Via Local Application of Tranexamic Acid to Target Bacterial-mediated Plasminogen Activation , 2019, Annals of surgery.

[3]  A. Gamian,et al.  Distinct Chemokine Dynamics in Early Postoperative Period after Open and Robotic Colorectal Surgery , 2019, Journal of clinical medicine.

[4]  T. Keck,et al.  Influence of Anastomotic Leak After Elective Colorectal Cancer Resection on Survival and Local Recurrence: A Propensity Score Analysis , 2019, Diseases of the colon and rectum.

[5]  J. Grainger,et al.  Systemic instruction of cell-mediated immunity by the intestinal microbiome , 2018, F1000Research.

[6]  R. Crolla,et al.  Oncologic outcome and recurrence rate following anastomotic leakage after curative resection for colorectal cancer. , 2018, Surgical oncology.

[7]  M. McEvoy,et al.  Ketorolac Use and Anastomotic Leak in Elective Colorectal Surgery: A Detailed Analysis , 2018, Diseases of the colon and rectum.

[8]  A. Zaborin,et al.  Novel de novo synthesized phosphate carrier compound ABA‐PEG20k‐Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic anastomotic leak in an experimental model , 2018, The British journal of surgery.

[9]  J. Alverdy.  Microbiome Medicine: This Changes Everything. , 2018, Journal of the American College of Surgeons.

[10]  P. Sánchez-Velázquez,et al.  Postoperative intra-abdominal infection is an independent prognostic factor of disease-free survival and disease-specific survival in patients with stage II colon cancer , 2018, Clinical and Translational Oncology.

[11]  K. Ruckstuhl,et al.  Diversity of gastrointestinal helminths in Dall's sheep and the negative association of the abomasal nematode, Marshallagia marshalli, with fitness indicators , 2018, PloS one.

[12]  Joon-Oh Park,et al.  Anastomotic Leak Does Not Impact Oncologic Outcomes After Preoperative Chemoradiotherapy and Resection for Rectal Cancer , 2017, Annals of surgery.

[13]  Nadeem N. Haddad,et al.  Perioperative use of nonsteroidal anti-inflammatory drugs and the risk of anastomotic failure in emergency general surgery. , 2017, The journal of trauma and acute care surgery.

[14]  Zhouqiao Wu,et al.  Definition of colorectal anastomotic leakage: A consensus survey among Dutch and Chinese colorectal surgeons , 2017, World journal of gastroenterology.

[15]  J. Lange,et al.  Effects of adipose stem cell sheets on colon anastomotic leakage in an experimental model: Proof of principle. , 2017, Biomaterials.

[16]  K. Guyton,et al.  Media from macrophages co-incubated with Enterococcus faecalis induces epithelial cell monolayer reassembly and altered cell morphology , 2017, PloS one.

[17]  L. Feldman,et al.  Clinical practice guideline for enhanced recovery after colon and rectal surgery from the American Society of Colon and Rectal Surgeons (ASCRS) and Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) , 2017, Surgical Endoscopy.

[18]  James N. Luo,et al.  Preparing the Bowel for Surgery: Learning from the Past and Planning for the Future. , 2017, Journal of the American College of Surgeons.

[19]  Julang Li,et al.  In a Neonatal Piglet Model of Intestinal Failure, Administration of Antibiotics and Lack of Enteral Nutrition Have a Greater Impact on Intestinal Microflora Than Surgical Resection Alone , 2017, JPEN. Journal of parenteral and enteral nutrition.

[20]  R. Uozumi,et al.  Multicenter analysis of impact of anastomotic leakage on long‐term oncologic outcomes after curative resection of colon cancer , 2017, Surgery.

[21]  M. Poeze,et al.  Cyclooxygenase-2 Is Essential for Colorectal Anastomotic Healing , 2017, Annals of surgery.

[22]  R. Klabbers,et al.  Oral Polyphosphate Suppresses Bacterial Collagenase Production and Prevents Anastomotic Leak Due to Serratia marcescens and Pseudomonas aeruginosa , 2017, Annals of surgery.

[23]  Y. Panis,et al.  Oncological impact of anastomotic leakage after laparoscopic mesorectal excision , 2017, The British journal of surgery.

[24]  G. Nolan,et al.  Regulation of IL-12p40 by HIF controls Th1/Th17 responses to prevent mucosal inflammation , 2017, Mucosal Immunology.

[25]  E. Angenete,et al.  Diagnosis, treatment, and consequences of anastomotic leakage in colorectal surgery , 2017, International Journal of Colorectal Disease.

[26]  T. Rockall,et al.  A collaborative review of the current concepts and challenges of anastomotic leaks in colorectal surgery , 2017, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[27]  J. Fleshman,et al.  Emerging Trends in the Etiology, Prevention, and Treatment of Gastrointestinal Anastomotic Leakage , 2016, Journal of Gastrointestinal Surgery.

[28]  E. Grice,et al.  Redefining the Chronic-Wound Microbiome: Fungal Communities Are Prevalent, Dynamic, and Associated with Delayed Healing , 2016, mBio.

[29]  Zhouqiao Wu,et al.  Integrated approach to colorectal anastomotic leakage: Communication, infection and healing disturbances. , 2016, World journal of gastroenterology.

[30]  T. Treasure,et al.  Meta-analysis of colorectal cancer follow-up after potentially curative resection , 2016, The British journal of surgery.

[31]  R. Costi,et al.  Anastomotic recurrence of colon cancer: Genetic analysis challenges the widely held theories of cancerous cells’ intraluminal implantation and metachronous carcinogenesis , 2016, Journal of surgical oncology.

[32]  Y. Sakai,et al.  Preoperative, intraoperative and postoperative risk factors for anastomotic leakage after laparoscopic low anterior resection with double stapling technique anastomosis. , 2016, World journal of gastroenterology.

[33]  K. Honda,et al.  The microbiota in adaptive immune homeostasis and disease , 2016, Nature.

[34]  N. Kim,et al.  Impact of anastomotic leakage on long-term oncologic outcome and its related factors in rectal cancer , 2016, Medicine.

[35]  Dongfeng Zhang,et al.  Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients' survival? A pilot study on relevant mechanism , 2016, Oncotarget.

[36]  A. Hill,et al.  Peritoneal Cytokine Levels Can Predict Anastomotic Leak on the First Postoperative Day. , 2016, Diseases of the colon and rectum.

[37]  D. Margolin,et al.  Management of Colorectal Anastomotic Leak , 2016, Clinics in Colon and Rectal Surgery.

[38]  N. Tran,et al.  Gut Microbiota Drive Autoimmune Arthritis by Promoting Differentiation and Migration of Peyer's Patch T Follicular Helper Cells. , 2016, Immunity.

[39]  F. Dekker,et al.  Association Between the Most Frequent Complications After Surgery for Stage I–III Colon Cancer and Short-Term Survival, Long-Term Survival, and Recurrences , 2016, Annals of Surgical Oncology.

[40]  W. Schreurs,et al.  Risk of anastomotic leakage with nonsteroidal anti-inflammatory drugs within an enhanced recovery program , 2016, Journal of Gastrointestinal Surgery.

[41]  R. Bruno,et al.  Beyond the gut bacterial microbiota: The gut virome , 2016, Journal of medical virology.

[42]  A. Heriot,et al.  Anastomotic Leaks After Restorative Resections for Rectal Cancer Compromise Cancer Outcomes and Survival , 2016, Diseases of the colon and rectum.

[43]  M. Rutegård,et al.  Non-Steroidal Anti-Inflammatory Drug Use and Risk of Anastomotic Leakage after Anterior Resection: A Protocol-Based Study , 2016, Digestive Surgery.

[44]  N. Bouvy,et al.  Colorectal anastomotic healing: why the biological processes that lead to anastomotic leakage should be revealed prior to conducting intervention studies , 2015, BMC Gastroenterology.

[45]  J. Carmichael,et al.  Contemporary management of anastomotic leak after colon surgery: assessing the need for reoperation. , 2015, American journal of surgery.

[46]  Y. Kim,et al.  The impact of anastomotic leakage on oncologic outcomes and the receipt and timing of adjuvant chemotherapy after colorectal cancer surgery. , 2015, International journal of surgery.

[47]  J. van Praagh,et al.  Intestinal microbiota and anastomotic leakage of stapled colorectal anastomoses: a pilot study , 2015, Surgical Endoscopy.

[48]  S. Colgan,et al.  Physiologic hypoxia and oxygen homeostasis in the healthy intestine. A Review in the Theme: Cellular Responses to Hypoxia. , 2015, American journal of physiology. Cell physiology.

[49]  G. Krapohl,et al.  Nonsteroidal Anti-Inflammatory Drugs , 2019, CRC Handbook of Ototoxicity.

[50]  C. Yu,et al.  The types of anastomotic leakage that develop following anterior resection for rectal cancer demonstrate distinct characteristics and oncologic outcomes , 2015, International Journal of Colorectal Disease.

[51]  D. Hervás,et al.  Risk Factors for Anastomotic Leak After Colon Resection for Cancer: Multivariate Analysis and Nomogram From a Multicentric, Prospective, National Study With 3193 Patients. , 2015, Annals of surgery.

[52]  A. Gasbarrini,et al.  The human gut microbiota and virome: Potential therapeutic implications , 2015, Digestive and Liver Disease.

[53]  Jinling Huang,et al.  Horizontal gene transfer: building the web of life , 2015, Nature Reviews Genetics.

[54]  Beth A. Glenn,et al.  Cluster-Randomized Trial to Increase Hepatitis B Testing among Koreans in Los Angeles , 2015, Cancer Epidemiology, Biomarkers & Prevention.

[55]  Y. Xiong,et al.  Effect of non-steroidal anti-inflammatory drugs on the increasing the incidence of colonic anastomosis in rats. , 2015, International journal of clinical and experimental pathology.

[56]  James N. Luo,et al.  Collagen degradation and MMP9 activation by Enterococcus faecalis contribute to intestinal anastomotic leak , 2015, Science Translational Medicine.

[57]  A. Focà,et al.  Gut Inflammation and Immunity: What Is the Role of the Human Gut Virome? , 2015, Mediators of inflammation.

[58]  R. Steele,et al.  Systematic review of preoperative, intraoperative and postoperative risk factors for colorectal anastomotic leaks , 2015, The British journal of surgery.

[59]  O. Faiz,et al.  The Impact of Anastomotic Leak and Its Treatment on Cancer Recurrence and Survival Following Elective Colorectal Cancer Resection , 2015, World Journal of Surgery.

[60]  E. Espin,et al.  Oncological outcome following anastomotic leak in rectal surgery , 2015, The British journal of surgery.

[61]  D. Flum,et al.  Nonsteroidal anti-inflammatory drugs and the risk for anastomotic failure: a report from Washington State's Surgical Care and Outcomes Assessment Program (SCOAP). , 2015, JAMA surgery.

[62]  S. Mojal,et al.  Postoperative intra-abdominal infection and colorectal cancer recurrence: a prospective matched cohort study of inflammatory and angiogenic responses as mechanisms involved in this association. , 2015, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[63]  Florence E. Turrentine,et al.  Morbidity, mortality, cost, and survival estimates of gastrointestinal anastomotic leaks. , 2015, Journal of the American College of Surgeons.

[64]  Shusen Zheng,et al.  Application of metagenomics in the human gut microbiome. , 2015, World journal of gastroenterology.

[65]  J. Chewning,et al.  Development and Survival of Th17 Cells within the Intestines: The Influence of Microbiome- and Diet-Derived Signals , 2014, The Journal of Immunology.

[66]  P. Gianello,et al.  Improvement of Subcutaneous Bioartificial Pancreas Vascularization and Function by Coencapsulation of Pig Islets and Mesenchymal Stem Cells in Primates , 2014, Cell transplantation.

[67]  R. Messeguer,et al.  Postoperative Peritoneal Infection Enhances Migration and Invasion Capacities of Tumor Cells In Vitro: An Insight Into the Association Between Anastomotic Leak and Recurrence After Surgery for Colorectal Cancer , 2014, Annals of surgery.

[68]  S. Christley,et al.  Intestinal anastomotic injury alters spatially defined microbiome composition and function , 2014, Microbiome.

[69]  G. Baatrup,et al.  Cytokine response in peripheral blood indicates different pathophysiological mechanisms behind anastomotic leakage after low anterior resection: a pilot study , 2014, Techniques in Coloproctology.

[70]  A. Vannelli,et al.  Anastomotic leakage following colorectal resection for cancer: how to define, manage and treat it. , 2014, Minerva Chirurgica.

[71]  F. Quereshy,et al.  Perioperative Nonselective Non-steroidal Anti-inflammatory Drugs Are Not Associated with Anastomotic Leakage After Colorectal Surgery , 2014, Journal of Gastrointestinal Surgery.

[72]  R. McLeod,et al.  NSAID Use and Anastomotic Leaks Following Elective Colorectal Surgery: a Matched Case-Control Study , 2014, Journal of Gastrointestinal Surgery.

[73]  J. Huh,et al.  Oncologic impact of anastomotic leakage in rectal cancer surgery according to the use of fibrin glue: case-control study using propensity score matching method. , 2014, American journal of surgery.

[74]  P. Krarup,et al.  Anastomotic Leak Increases Distant Recurrence and Long-Term Mortality After Curative Resection for Colonic Cancer: A Nationwide Cohort Study , 2014, Annals of surgery.

[75]  U. Neumann,et al.  Influence of CD68+ macrophages and neutrophils on anastomotic healing following laparoscopic sigmoid resection due to diverticulitis , 2014, International Journal of Colorectal Disease.

[76]  M. Ebert,et al.  Fusobacterium nucleatum associates with stages of colorectal neoplasia development, colorectal cancer and disease outcome , 2014, European Journal of Clinical Microbiology & Infectious Diseases.

[77]  J. Raufman,et al.  The Role of Matrix Metalloproteinases in Colorectal Cancer , 2014, Cancers.

[78]  F. Marincola,et al.  Commensal Bacteria Control Cancer Response to Therapy by Modulating the Tumor Microenvironment , 2013, Science.

[79]  Gary An,et al.  Agent-based model of epithelial host-pathogen interactions in anastomotic leak. , 2013, The Journal of surgical research.

[80]  C. Carlson,et al.  COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations , 2013, Cancer Causes & Control.

[81]  S. Arıkan,et al.  Treatment of ischemic colonic anastomoses with systemic transplanted bone marrow derived mesenchymal stem cells. , 2013, European review for medical and pharmacological sciences.

[82]  D. Kobayashi,et al.  Significant Changes in the Intestinal Environment After Surgery in Patients with Colorectal Cancer , 2013, Journal of Gastrointestinal Surgery.

[83]  B. Finlay,et al.  Manipulation of innate immunity by a bacterial secreted peptide: Lantibiotic nisin Z is selectively immunomodulatory , 2013, Innate immunity.

[84]  C. Carlson,et al.  Genetic variation in the lipoxygenase pathway and risk of colorectal neoplasia , 2013, Genes, chromosomes & cancer.

[85]  P. Gianello,et al.  Galactosyl-knock-out engineered pig as a xenogenic donor source of adipose MSCs for bone regeneration. , 2013, Biomaterials.

[86]  J. Guillem,et al.  Anastomotic Leak Is Not Associated With Oncologic Outcome in Patients Undergoing Low Anterior Resection for Rectal Cancer , 2012, Annals of surgery.

[87]  J. Rosenberg,et al.  Postoperative use of non-steroidal anti-inflammatory drugs in patients with anastomotic leakage requiring reoperation after colorectal resection: cohort study based on prospective data , 2012, BMJ : British Medical Journal.

[88]  A. Zaborin,et al.  Intestinal Tissues Induce an SNP Mutation in Pseudomonas aeruginosa That Enhances Its Virulence: Possible Role in Anastomotic Leak , 2012, PloS one.

[89]  Kwang Hee Kim,et al.  Adipose-tissue-derived Stem Cells Enhance the Healing of Ischemic Colonic Anastomoses: An Experimental Study in Rats , 2012, Journal of the Korean Society of Coloproctology.

[90]  M. Sosef,et al.  Risk of anastomotic leakage with non‐steroidal anti‐inflammatory drugs in colorectal surgery , 2012, The British journal of surgery.

[91]  P. Gianello,et al.  The enhanced performance of bone allografts using osteogenic-differentiated adipose-derived mesenchymal stem cells. , 2011, Biomaterials.

[92]  R. Hannon,et al.  The role of carbohydrate drinks in pre-operative nutrition for elective colorectal surgery. , 2011, Annals of the Royal College of Surgeons of England.

[93]  Z. Krivokapic,et al.  Matrix metalloproteinase-2 (MMP-2) and -9 (MMP-9) in preoperative serum as independent prognostic markers in patients with colorectal cancer , 2011, Molecular and Cellular Biochemistry.

[94]  A. Mirnezami,et al.  Increased Local Recurrence and Reduced Survival From Colorectal Cancer Following Anastomotic Leak: Systematic Review and Meta-Analysis , 2011, Annals of surgery.

[95]  L. Damber,et al.  Anastomotic leakage after surgery for rectal cancer: a risk factor for local recurrence, distant metastasis and reduced cancer‐specific survival? , 2011, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[96]  D. Cassini,et al.  Anastomotic leakage and septic complications: impact on local recurrence in surgery of low rectal cancer. , 2011, Annali italiani di chirurgia.

[97]  J. Nishimura,et al.  Exfoliated malignant cells at the anastomosis site in colon cancer surgery: the impact of surgical bowel occlusion and intraluminal cleaning , 2011, International Journal of Colorectal Disease.

[98]  J. Rosenberg,et al.  Effect of Diclofenac on Cyclooxygenase-2 Levels and Early Breaking Strength of Experimental Colonic Anastomoses and Skin Incisions , 2010, European Surgical Research.

[99]  Shouguang Jin,et al.  MexT Regulates the Type III Secretion System through MexS and PtrC in Pseudomonas aeruginosa , 2010, Journal of bacteriology.

[100]  Todd Davidson,et al.  Generation of Pathogenic Th17 Cells in the Absence of TGF-β Signaling , 2010, Nature.

[101]  S. Mazmanian,et al.  Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis , 2010, Proceedings of the National Academy of Sciences.

[102]  Christophe Benoist,et al.  Gut-residing segmented filamentous bacteria drive autoimmune arthritis via T helper 17 cells. , 2010, Immunity.

[103]  Hongbing Shen,et al.  Potentially functional COX‐2 −1195G>A polymorphism increases the risk of digestive system cancers: A meta‐analysis , 2010, Journal of gastroenterology and hepatology.

[104]  B. Parry,et al.  Randomized controlled trial of preoperative oral carbohydrate treatment in major abdominal surgery , 2010, The British journal of surgery.

[105]  Q. Wang,et al.  Randomized clinical trial to compare the effects of preoperative oral carbohydrate versus placebo on insulin resistance after colorectal surgery , 2010, The British journal of surgery.

[106]  B. Zhou,et al.  Inflammation: A driving force speeds cancer metastasis , 2009 .

[107]  H. Putter,et al.  Multicentre analysis of oncological and survival outcomes following anastomotic leakage after rectal cancer surgery , 2009, The British journal of surgery.

[108]  Tsutomu Yoshida,et al.  Appearance of epithelial and stromal genomic instability in background colorectal mucosa of sporadic colorectal cancer patients: relation to age and gender , 2009, Journal of Gastroenterology.

[109]  H. Kehlet,et al.  Cyclo‐oxygenase 2 inhibitors and the risk of anastomotic leakage after fast‐track colonic surgery , 2009, The British journal of surgery.

[110]  S. Mazmanian,et al.  The gut microbiota shapes intestinal immune responses during health and disease , 2009, Nature Reviews Immunology.

[111]  C. V. D. van de Velde,et al.  Improved diagnosis and treatment of anastomotic leakage after colorectal surgery. , 2009, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

[112]  C. Sears.  Enterotoxigenic Bacteroides fragilis: a Rogue among Symbiotes , 2009, Clinical Microbiology Reviews.

[113]  S. Sainsbury,et al.  T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. , 2009, Immunity.

[114]  I. Lavery,et al.  The Impact of Anastomotic Leak and Intra-Abdominal Abscess on Cancer-Related Outcomes After Resection for Colorectal Cancer: A Case Control Study , 2009, Diseases of the colon and rectum.

[115]  R. Lothe,et al.  Gene methylation profiles of normal mucosa, and benign and malignant colorectal tumors identify early onset markers , 2008, Molecular Cancer.

[116]  R. Medzhitov.  Origin and physiological roles of inflammation , 2008, Nature.

[117]  P. Allavena,et al.  Cancer-related inflammation , 2008, Nature.

[118]  S. Colgan,et al.  Mucosal protection by hypoxia‐inducible factor (HIF) prolyl hydroxylase inhibition , 2008 .

[119]  M. Secic,et al.  Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study , 2008, International Journal of Colorectal Disease.

[120]  A. Darzi,et al.  Standardized Algorithms for Management of Anastomotic Leaks and Related Abdominal and Pelvic Abscesses After Colorectal Surgery , 2008, World Journal of Surgery.

[121]  M. Teixeira,et al.  The Required Role of Endogenously Produced Lipoxin A4 and Annexin-1 for the Production of IL-10 and Inflammatory Hyporesponsiveness in Mice1 , 2007, The Journal of Immunology.

[122]  O. Ljungqvist,et al.  Randomized clinical trial of the effect of preoperative oral carbohydrate treatment on postoperative whole‐body protein and glucose kinetics , 2007, The British journal of surgery.

[123]  J. Ho,et al.  Anastomotic Leakage is Associated with Poor Long-Term Outcome in Patients After Curative Colorectal Resection for Malignancy , 2007, Journal of Gastrointestinal Surgery.

[124]  D. Watson,et al.  Pre‐operative oral carbohydrate loading in colorectal surgery: a randomized controlled trial , 2006, Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland.

[125]  J. Paddison,et al.  DIFFERENTIAL PRODUCTION OF CYTOKINES FOLLOWING COLORECTAL SURGERY , 2006, ANZ journal of surgery.

[126]  Y. Bae,et al.  Human Adipose Tissue-Derived Mesenchymal Stem Cells Improve Postnatal Neovascularization in a Mouse Model of Hindlimb Ischemia , 2006, Cellular Physiology and Biochemistry.

[127]  Hermann Eichler,et al.  Comparative Analysis of Mesenchymal Stem Cells from Bone Marrow, Umbilical Cord Blood, or Adipose Tissue , 2006, Stem cells.

[128]  C. Boland,et al.  INFECTION, INFLAMMATION, AND GASTROINTESTINAL CANCER , 2005, Gut.

[129]  C. Ulrich,et al.  PTGS2 (COX-2) −765G > C Promoter Variant Reduces Risk of Colorectal Adenoma among Nonusers of Nonsteroidal Anti-inflammatory Drugs , 2005, Cancer Epidemiology Biomarkers & Prevention.

[130]  G. Branagan,et al.  Prognosis After Anastomotic Leakage in Colorectal Surgery , 2005, Diseases of the colon and rectum.

[131]  Timo K. Korhonen,et al.  Bacterial metastasis: the host plasminogen system in bacterial invasion. , 2005, Trends in microbiology.

[132]  K. Pumiglia,et al.  Integrin α3β1 directs the stabilization of a polarized lamellipodium in epithelial cells through activation of Rac1 , 2004, Journal of Cell Science.

[133]  N. Konishi,et al.  C-Reactive Protein as a Prognostic Variable That Reflects Uncontrolled Up-Regulation of the IL-1-IL-6 Network System in Colorectal Carcinoma , 2004, Digestive Diseases and Sciences.

[134]  J. Bruce,et al.  Systematic review of the definition and measurement of anastomotic leak after gastrointestinal surgery , 2001, The British journal of surgery.

[135]  Y. Jang,et al.  Temporal activity of plasminogen activators and matrix metalloproteinases during cutaneous wound repair. , 1999, Surgery.

[136]  R. Costi,et al.  Risk factors of local recurrence of colorectal cancer: a multivariate study. , 1998, Hepato-gastroenterology.

[137]  H. Lijnen,et al.  Regulation of Gelatinase Activity in Mice with Targeted Inactivation of Components of the Plasminogen/Plasmin System , 1998, Thrombosis and Haemostasis.

[138]  R. James,et al.  Definition of local recurrence after surgery for rectal carcinoma , 1995, The British journal of surgery.

[139]  D. Galloway,et al.  Anastomotic leaks in colorectal cancer surgery: a risk factor for recurrence? , 1991, International Journal of Colorectal Disease.

[140]  Taylor Ew,et al.  Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. , 1991 .

[141]  P. Gibbs,et al.  Impact of anastomotic leak on recurrence and survival after colorectal cancer surgery: a BioGrid Australia analysis , 2018, ANZ journal of surgery.

[142]  Y. Doki,et al.  The Severity of Anastomotic Leakage May Negatively Impact the Long-term Prognosis of Colorectal Cancer. , 2018, Anticancer research.

[143]  Y. Cong,et al.  Microbiota metabolite short chain fatty acids, GPCR, and inflammatory bowel diseases , 2016, Journal of Gastroenterology.

[144]  K. Yamashita,et al.  Anastomotic Leakage Contributes to the Risk for Systemic Recurrence in Stage II Colorectal Cancer , 2010, Journal of Gastrointestinal Surgery.

[145]  S. Arıkan,et al.  Mesenchymal stem cells improve the healing of ischemic colonic anastomoses (experimental study) , 2010, Langenbeck's Archives of Surgery.

[146]  R. Whitehead,et al.  Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration. , 2008, American journal of physiology. Gastrointestinal and liver physiology.

[147]  E. Taylor,et al.  Proposed definitions for the audit of postoperative infection: a discussion paper. Surgical Infection Study Group. , 1991, Annals of the Royal College of Surgeons of England.

[148]  J. Hale.  Viable intraluminal tumour cells and local/regional tumour growth in experimental colon cancer. , 1989, Annals of the Royal College of Surgeons of England.