Differences in the relative involvement of peripherally released interleukin (IL)-6, brain IL-1β and prostanoids in mediating lipopolysaccharide-induced fever and sickness behavior

[1]  Mao-Tsun Lin,et al.  Interleukin-1 receptor antagonist inhibits the release of glutamate, hydroxyl radicals, and prostaglandin E(2) in the hypothalamus during pyrogen-induced fever in rabbits. , 2010, European journal of pharmacology.

[2]  V. Perry,et al.  The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1 , 2010, Brain, Behavior, and Immunity.

[3]  A. Jean,et al.  Prostaglandins and sickness behavior: Old story, new insights , 2009, Physiology & Behavior.

[4]  A. Blomqvist,et al.  The role of interleukin-6 in lipopolysaccharide-induced fever by mechanisms independent of prostaglandin E2. , 2009, Endocrinology.

[5]  R. Dantzer,et al.  Central nervous action of interleukin‐1 mediates activation of limbic structures and behavioural depression in response to peripheral administration of bacterial lipopolysaccharide , 2008, European Journal of Neuroscience.

[6]  S. Poole,et al.  Interleukin (IL)-6 and IL-1β act synergistically within the brain to induce sickness behavior and fever in rats , 2008, Brain, Behavior, and Immunity.

[7]  V. Perry,et al.  Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines , 2007, Brain, Behavior, and Immunity.

[8]  E. Zorrilla,et al.  Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency , 2007, Proceedings of the National Academy of Sciences.

[9]  L. Natarajan,et al.  The association between fatigue and inflammatory marker levels in cancer patients: A quantitative review , 2007, Brain, Behavior, and Immunity.

[10]  C. Coimbra,et al.  Tryptophan-induced central fatigue in exercising rats is related to serotonin content in preoptic area , 2007, Neuroscience Letters.

[11]  A. Blomqvist,et al.  IL-1beta and LPS induce anorexia by distinct mechanisms differentially dependent on microsomal prostaglandin E synthase-1. , 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

[12]  S. Poole,et al.  Circulating interleukin-6 induces fever through a STAT3-linked activation of COX-2 in the brain. , 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

[13]  S. Poole,et al.  Interleukin-6 and leptin mediate lipopolysaccharide-induced fever and sickness behavior , 2006, Physiology & Behavior.

[14]  J. Roth,et al.  Molecular aspects of fever and hyperthermia. , 2006, Neurologic clinics.

[15]  C. Dinarello.  An IL-1 family member requires caspase-1 processing and signals through the ST2 receptor. , 2005, Immunity.

[16]  L. Staudt,et al.  Clinical Trials and Observations , 2007 .

[17]  L. Moreland.  Humanized anti-interleukin-6 receptor antibody , 2005 .

[18]  J. W. Rudy,et al.  Neonatal Infection-Induced Memory Impairment after Lipopolysaccharide in Adulthood Is Prevented via Caspase-1 Inhibition , 2005, The Journal of Neuroscience.

[19]  J. Roth,et al.  Localized vs. systemic inflammation in guinea pigs: a role for prostaglandins at distinct points of the fever induction pathways? , 2005, American journal of physiology. Regulatory, integrative and comparative physiology.

[20]  C. Blatteis,et al.  Cytokines, PGE2 and endotoxic fever: a re-assessment. , 2005, Prostaglandins & other lipid mediators.

[21]  R. Omdal,et al.  The effect of interleukin-1 blockade on fatigue in rheumatoid arthritis—a pilot study , 2005, Rheumatology International.

[22]  Erika Pedrosa,et al.  Acute diclofenac treatment attenuates lipopolysaccharide-induced alterations to basic reward behavior and HPA axis activation in rats , 2005, Psychopharmacology.

[23]  J. Roth,et al.  Is interleukin-6 the necessary pyrogenic cytokine? , 2004 .

[24]  J. Roth,et al.  Nuclear translocation of the transcription factor STAT3 in the guinea pig brain during systemic or localized inflammation , 2004, The Journal of physiology.

[25]  A. A. Romanovsky,et al.  Prostaglandin E2 as a mediator of fever: synthesis and catabolism. , 2004, Frontiers in bioscience : a journal and virtual library.

[26]  T. Bártfai,et al.  Cytokines and fever. , 2004, Frontiers in bioscience : a journal and virtual library.

[27]  T. Garland,et al.  Patterns of brain activity associated with variation in voluntary wheel-running behavior. , 2003, Behavioral neuroscience.

[28]  T. Pollmächer,et al.  Endotoxin-induced changes in food consumption in healthy volunteers are associated with TNF-α and IL-6 secretion , 2002, Psychoneuroendocrinology.

[29]  L. Muglia,et al.  COX-2 inhibition attenuates anorexia during systemic inflammation without impairing cytokine production. , 2002, American journal of physiology. Endocrinology and metabolism.

[30]  Yasuyoshi Watanabe,et al.  Pyrogenic cytokines injected into the rat cerebral ventricle induce cyclooxygenase‐2 in brain endothelial cells and also upregulate their receptors , 2001, The European journal of neuroscience.

[31]  C. Plata-salamán.  Cytokines and feeding. , 1998, International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity.

[32]  J. Roth,et al.  Influence of systemic treatment with cyclooxygenase inhibitors on lipopolysaccharide-induced fever and circulating levels of cytokines and cortisol in guinea-pigs , 2001, Pflügers Archiv.

[33]  S. Maier,et al.  Effects of vagotomy on lipopolysaccharide-induced brain interleukin-1β protein in rats , 2000, Autonomic Neuroscience.

[34]  R. Dantzer,et al.  Role of IL-6 in cytokine-induced sickness behavior a study with IL-6 deficient mice , 2000, Physiology & Behavior.

[35]  N. Rothwell,et al.  Circulating interleukin‐6 mediates the febrile response to localised inflammation in rats , 2000, The Journal of physiology.

[36]  R. Dantzer,et al.  Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression. , 2000, American journal of physiology. Regulatory, integrative and comparative physiology.

[37]  E. Clementi,et al.  Inhibition of Caspase-1-Like Activity by Ac-Tyr-Val-Ala-Asp-Chloromethyl Ketone Induces Long-Lasting Neuroprotection in Cerebral Ischemia through Apoptosis Reduction and Decrease of Proinflammatory Cytokines , 2000, The Journal of Neuroscience.

[38]  Y. Shima,et al.  Improvement in Castleman's disease by humanized anti-interleukin-6 receptor antibody therapy. , 2000, Blood.

[39]  C. Ball,et al.  Rat tumour necrosis factor-alpha: expression in recombinant Pichia pastoris, purification, characterization and development of a novel ELISA. , 1999, European cytokine network.

[40]  A. Świergiel,et al.  The Roles of IL-1, IL-6, and TNFα in the Feeding Responses to Endotoxin and Influenza Virus Infection in Mice , 1999, Brain, Behavior, and Immunity.

[41]  N. Rothwell,et al.  Brain sites of action of endogenous interleukin‐1 in the febrile response to localized inflammation in the rat , 1999, The Journal of physiology.

[42]  P. Ghezzi,et al.  Peripheral Effects of Centrally Administered Interleukin-1β in Mice in Relation to Its Clearance from the Brain into the Blood and Tissue Distribution , 1999, Neuroimmunomodulation.

[43]  R. Dantzer,et al.  Temporal and spatial relationships between lipopolysaccharide-induced expression of fos, interleukin-1 β and inducible nitric oxide synthase in rat brain , 1999, Neuroscience.

[44]  C. Ball,et al.  Rat interleukin 6: expression in recombinant Escherichia coli, purification and development of a novel ELISA. , 1999, Cytokine.

[45]  M. Herkenham,et al.  Time course and localization patterns of interleukin-1β messenger rna expression in brain and pituitary after peripheral administration of lipopolysaccharide , 1998, Neuroscience.

[46]  L. Leon,et al.  IL‐6 and IL‐1β in Fever: Studies Using Cytokine‐Deficient (Knockout) Mice a , 1998 .

[47]  J. Born,et al.  Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men. , 1998, The Journal of clinical endocrinology and metabolism.

[48]  S. Hopkins,et al.  Sites of action of IL‐1 in the development of fever and cytokine responses to tissue inflammation in the rat , 1997, British journal of pharmacology.

[49]  C. Plata-salamán,et al.  Anorexia induced by chronic central administration of cytokines at estimated pathophysiological concentrations , 1996, Physiology and Behavior.

[50]  V. Poli,et al.  Interleukin (IL)-6 gene expression in the central nervous system is necessary for fever response to lipopolysaccharide or IL-1 beta: a study on IL-6-deficient mice , 1996, The Journal of experimental medicine.

[51]  N. Rothwell,et al.  Interleukin-1 receptor antagonist inhibits endotoxin fever and systemic interleukin-6 induction in the rat. , 1996, The American journal of physiology.

[52]  R. Dantzer,et al.  Subdiaphragmatic vagotomy blocks induction of IL-1 beta mRNA in mice brain in response to peripheral LPS. , 1995, The American journal of physiology.

[53]  G. Fantuzzi,et al.  Defective inflammatory response in interleukin 6-deficient mice , 1994, The Journal of experimental medicine.

[54]  R. Dantzer,et al.  Effects of lipopolysaccharide on food-motivated behavior in the rat are not blocked by an interleukin-1 receptor antagonist , 1992, Neuroscience Letters.

[55]  A. Dunn.  Endotoxin-induced activation of cerebral catecholamine and serotonin metabolism: comparison with interleukin-1. , 1992, The Journal of pharmacology and experimental therapeutics.

[56]  R. Dantzer,et al.  Effects of interleukin-1 receptor antagonist on the behavioral effects of lipopolysaccharide in rat , 1992, Brain Research.

[57]  C. Blatteis,et al.  Differential effects of cytokines on thermosensitive neurons in guinea pig preoptic area slices. , 1991, American Journal of Physiology.

[58]  C. Dinarello,et al.  Interleukin-6 as an endogenous pyrogen: induction of prostaglandin E2 in brain but not in peripheral blood mononuclear cells , 1991, Brain Research.

[59]  R. Cooper,et al.  Relationships between local inflammation, interleukin‐6 concentration and the acute phase protein response in arthritis patients , 1991, European journal of clinical investigation.

[60]  B. Hart.  Biological basis of the behavior of sick animals , 1988, Neuroscience & Biobehavioral Reviews.

[61]  P. Lansdorp,et al.  Production of hybridoma growth factor by human monocytes , 1987, European journal of immunology.

[62]  G. Paxinos,et al.  The Rat Brain in Stereotaxic Coordinates , 1983 .

[63]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.