Refinement of clinical X-ray computed tomography (CT) scans containing metal implants

X-ray computed tomography (CT) data contains artefacts from many sources, with sufficient prominence to affect diagnostic utility when metal is present in the scans. These artefacts can be reduced, usually by the removal and in-filling of any sinogram data which has been affected by metal, and several such techniques have been proposed. Most of them are prone to introducing new artefacts into the CT data or may take a long time to correct the data. It is the purpose of this paper to introduce a new technique which is fast, yet can effectively remove most artefacts without introducing significant new ones. The new metal artefact reduction technique (RMAR) consists of an iterative refinement of the CT data by alternately forward- and back-projecting the part of the reconstruction near to metal. The forward-projection is corrected by making use of a prior derived from the reconstructed data which is independently estimated for each projection angle, and smoothed using a newly developed Bitonic filter. The new technique is compared with previously published (LI, NMAR, MDT) and commercial (O-MAR, IMAR) alternatives, quantitatively on phantom data, and qualitatively on a selection of clinical scans, mostly of the hip. The phantom data is from two recently published studies, enabling direct comparison with previous results. The results show an increased reduction of artefacts on the four phantom data sets tested. On two of the phantom data sets, RMAR is significantly better (p<0.001) than all other techniques; on one it is as good as any other technique, and on the last it is only beaten by the Metal Deletion Technique (p<0.001), which is significantly slower. On the clinical data sets, RMAR shows visually similar performance to MDT, with better preservation of bony features close to metal implants, but perhaps slightly reduced homogeneity in the far field. For typical CT data, RMAR can correct each image in 3-8s, which is more than one hundred times faster than MDT. The new technique is demonstrated to have performance at least as good as MDT, with both out-performing other approaches. However, it is much faster then the latter technique, and shows better preservation of data very close to metal.

[1]  Joseph A. O'Sullivan,et al.  Iterative deblurring for CT metal artifact reduction , 1996, IEEE Trans. Medical Imaging.

[2]  Taly Gilat Schmidt,et al.  Optimal "image-based" weighting for energy-resolved CT. , 2009, Medical physics.

[3]  Francesco C Stingo,et al.  An evaluation of three commercially available metal artifact reduction methods for CT imaging , 2015, Physics in medicine and biology.

[4]  Dimitre Hristov,et al.  Clinical evaluation of the iterative metal artifact reduction algorithm for CT simulation in radiotherapy. , 2015, Medical physics.

[5]  D. Fleischmann,et al.  Evaluation of two iterative techniques for reducing metal artifacts in computed tomography. , 2011, Radiology.

[6]  Graham M. Treece The Bitonic Filter: Linear Filtering in an Edge-Preserving Morphological Framework , 2016, IEEE Transactions on Image Processing.

[7]  Rainer Raupach,et al.  Normalized Metal Artifact Reduction in Head and Neck Computed Tomography , 2012, Investigative radiology.

[8]  Matthias Franz,et al.  Reducing non-linear artifacts of multi-material objects in industrial 3D computed tomography , 2008 .

[9]  Paul Suetens Fundamentals of Medical Imaging , 2002 .

[10]  Rebecca Fahrig,et al.  Metal artifact correction for x-ray computed tomography using kV and selective MV imaging. , 2014, Medical physics.

[11]  F. Boas,et al.  CT artifacts: Causes and reduction techniques , 2012 .

[12]  Johan Nuyts,et al.  Metal artifact reduction in computed tomography using local models in an image block-iterative scheme. , 2012, Medical physics.

[13]  Steve B. Jiang,et al.  A hybrid metal artifact reduction algorithm for x-ray CT. , 2013, Medical physics.

[14]  Rainer Raupach,et al.  Frequency split metal artifact reduction (FSMAR) in computed tomography. , 2012, Medical physics.

[15]  Jin Keun Seo,et al.  Metal Artifact Reduction for Polychromatic X-ray CT Based on a Beam-Hardening Corrector , 2016, IEEE Transactions on Medical Imaging.

[16]  G. Soulez,et al.  Reduction of Beam-Hardening Artifacts in X-Ray CT , 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

[17]  J. Hsieh,et al.  An iterative approach to the beam hardening correction in cone beam CT. , 2000, Medical physics.

[18]  W. Kalender,et al.  Reduction of CT artifacts caused by metallic implants. , 1987 .

[19]  K J Batenburg,et al.  Iterative correction of beam hardening artifacts in CT. , 2011, Medical physics.

[20]  Rainer Raupach,et al.  Normalized metal artifact reduction (NMAR) in computed tomography. , 2010, Medical physics.

[21]  Jean-Michel Morel,et al.  A Review of Image Denoising Algorithms, with a New One , 2005, Multiscale Model. Simul..

[22]  Lei Dong,et al.  Reducing metal artifacts in cone-beam CT images by preprocessing projection data. , 2007, International journal of radiation oncology, biology, physics.

[23]  Sasa Mutic,et al.  Clinical evaluation of a commercial orthopedic metal artifact reduction tool for CT simulations in radiation therapy. , 2012, Medical physics.

[24]  J. Verburg,et al.  CT metal artifact reduction method correcting for beam hardening and missing projections , 2012, Physics in medicine and biology.

[25]  Sebastian Bickelhaupt,et al.  Reduction of metal artifacts from hip prostheses on CT images of the pelvis: value of iterative reconstructions. , 2013, Radiology.

[26]  Hanbean Youn,et al.  Generation of hybrid sinograms for the recovery of kV-CT images with metal artifacts for helical tomotherapy. , 2015, Medical physics.

[27]  J. Sijbers,et al.  An energy-based beam hardening model in tomography. , 2002, Physics in medicine and biology.

[28]  G. Andreisek,et al.  Metallic artefact reduction with monoenergetic dual-energy CT: systematic ex vivo evaluation of posterior spinal fusion implants from various vendors and different spine levels , 2012, European Radiology.

[29]  W. Kalender,et al.  Empirical cupping correction: a first-order raw data precorrection for cone-beam computed tomography. , 2006, Medical physics.

[30]  Prabhat Munshi,et al.  An improved algorithm for beam-hardening corrections in experimental X-ray tomography , 2008 .

[31]  Jacob Geleijns,et al.  Development and validation of segmentation and interpolation techniques in sinograms for metal artifact suppression in CT. , 2010, Medical physics.