[Effectiveness and safety evaluation of a cough stimulation device in early postoperative respiratory rehabilitation in cardiac surgery patients].

Postoperative respiratory complications in cardiac surgery patients occur in 22-30% of cases, mostly associated with ineffective cough and evacuation of bronchial secretion. OBJECTIVE To evaluate the effectiveness and safety of cough stimulation using the mechanical in- and exsufflator in the early postoperative period in cardiac surgery patients. MATERIAL AND METHODS The study included 37 patients; mean age was 57±12.3 years. Inclusion criteria: age over 18 years; post-extubation spontaneous breathing; fully conscious and cooperative; adequate gas exchange with oxygen therapy; adequate pain control (2 points or less on 10-point visual analogue scale). Exclusion criteria: need for re-intubation and mechanical ventilation; noninvasive mask ventilation; high-flow oxygen therapy; acute cerebrovascular event; uncontrolled bleeding; heart failure (inotropic score over 10); shock; need of extracorporeal blood purification; neuromuscular disease; pneumothorax, hydro- or hemothorax. Cough stimulation was performed using the mechanical in- and exsufflator Comfort Cough Plus («Seoil Pacific Corporation», Republic of Korea). The device provides cough stimulation after high-frequency vibrations transmitted through a special vest and lung tissue recruiting by changing the airways pressure of the gas mixture, delivered through the anesthesia face mask. RESULTS Cough stimulation device use was associated with an increase in the cough effectiveness; the number of patients with productive cough increased 8-fold, from 4 (10.8%) to 32 (86.4%), p=0.0000. The increase of blood oxygen saturation (SpO2) on room air from 92% to 96% (p=0.000001) and inspiratory capacity (IC) from 750 mL to 1200 mL (p=0.000002) was observed. The number of patients with IC of 1200-1500 mL increased 3-fold, and those with an IC over 1500 mL increased 2.6-fold. The proportion of patients with low oxygenation (SpO2 less than 92%) decreased 5-fold after the procedure (p=0.0011). Good tolerability and no side effects of the procedure were noted in all patients. CONCLUSION Impaired sputum expectoration early after cardiac surgery is observed in most patients and may cause low oxygenation. The main effects of the cough stimulation device were improvement of sputum expectoration and an increase in oxygenation. An increase in blood oxygen saturation and inspiratory capacity after a single procedure with this device was demonstrated. It resulted in a significantly decreased proportion of patients with respiratory insufficiency. No adverse effects of the procedure were observed.

[1]  M. Morozov,et al.  Experience of using the «Bark Vibrolung» device in the complex treatment of community-acquired pneumonia , 2021, Bulletin of the Russian Military Medical Academy.

[2]  G. Sbruzzi,et al.  Positive expiratory pressure in postoperative cardiac patients in intensive care: A randomized controlled trial , 2020, Clinical rehabilitation.

[3]  P. Squara,et al.  Diaphragm Paralysis After Cardiac Surgery: A Frequent Cause of Post-Operative Respiratory Failure , 2020 .

[4]  V. Vitomskyi,et al.  The Role of Respiratory Physical Therapy in the Rehabilitation of Patients after Cardiac Surgery , 2020 .

[5]  Lu-Lu Ma,et al.  Phrenic Nerve Injury Is a Differential Diagnosis of Hypoxemia after Video-Assisted Thoracoscopic Thymectomy: 2 Cases Report and Literature Review. , 2020, Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih.

[6]  M. Paul,et al.  "Risk factors for ventilator-associated pneumonia following cardiac surgery: case-control study". , 2020, The Journal of hospital infection.

[7]  A. Eremenko,et al.  Evaluation of effectiveness of vibroacoustic lung massage self-breathing in patients after cardiosurgical operations , 2020 .

[8]  Wanchai Wongkornrat,et al.  Effectiveness of Incentive Spirometry on Inspiratory Muscle Strength After Coronary Artery Bypass Graft Surgery. , 2019, Heart, lung & circulation.

[9]  M. Elçi,et al.  Effects of Minimal Extracorporeal Circulation on the Systemic Inflammatory Response and the Need for Transfusion after Coronary Bypass Grafting Surgery , 2019, Cardiology research and practice.

[10]  A. Eremenko,et al.  Postoperative acute respiratory failure in cardiac surgery. , 2019, Khirurgiia.

[11]  J. Bazin,et al.  Recruitment maneuvers in acute respiratory distress syndrome. , 2017, Annals of translational medicine.

[12]  M. Spalding,et al.  Ventilator-Associated Pneumonia , 2017, Critical Care Clinics.

[13]  R. Fernandez,et al.  Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation on Reintubation and Postextubation Respiratory Failure in High-Risk Patients: A Randomized Clinical Trial. , 2016, JAMA.

[14]  E. Nasiri,et al.  Frequency Rate of Atelectasis in Patients Following Coronary Artery Bypass Graft and Its Associated Factors at Mazandaran Heart Center in 2013-2014 , 2015, Global journal of health science.

[15]  A. Nicolini,et al.  Effectiveness of treatment with high-frequency chest wall oscillation in patients with bronchiectasis , 2013, BMC Pulmonary Medicine.

[16]  Ashish S Shah,et al.  Lung injury and acute respiratory distress syndrome after cardiac surgery. , 2013, The Annals of thoracic surgery.

[17]  M. Colmenero,et al.  Postoperative respiratory failure after cardiac surgery: use of noninvasive ventilation. , 2012, Journal of cardiothoracic and vascular anesthesia.

[18]  H. Khalil Treating TB in people with HIV , 2011 .

[19]  Array А. Романов,et al.  Коррекция нарушения оксигенирующей функции легких при ранней активизации кардиохирургических больных , 2009 .

[20]  G. Hedenstierna,et al.  Deep‐Breathing Exercises Reduce Atelectasis And Improve Pulmonary Function After Coronary Artery Bypass Surgery. , 2005, Chest.

[21]  A. Arifi,et al.  Pulmonary dysfunction after cardiac surgery. , 2002, Chest.

[22]  S. Wicky,et al.  Atelectasis Is a Major Cause of Hypoxemia and Shunt after Cardiopulmonary Bypass , 1997, Anesthesiology.