The RNA m6A binding protein YTHDF2 promotes the B cell to plasma cell transition
暂无分享,去创建一个
Louise S. Matheson | M. Screen | A. Saveliev | F. Salerno | David J. Turner | Martin Turner | Kamil R. Kranc | Hannah Lawson | David Wotherspoon
[1] David J. Turner,et al. RNA Binding Proteins As Regulators of Oxidative Stress Identified by a Targeted CRISPR-Cas9 Single Guide RNA Library , 2021, The CRISPR journal.
[2] A. Saveliev,et al. Efficient homing of antibody-secreting cells to the bone marrow requires RNA-binding protein ZFP36L1 , 2020, The Journal of experimental medicine.
[3] A. Mead,et al. The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function , 2020, The Journal of experimental medicine.
[4] J. Hanna,et al. B Cell Division Capacity in Germinal Centers Depends on Myc Transcript Stabilization Through m6A mRNA Methylation and IGF2BP3 Functions , 2020, bioRxiv.
[5] Hui-Lung Sun,et al. Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. , 2020, Cell reports.
[6] Samie R. Jaffrey,et al. A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA , 2020, Cell.
[7] D. Nowis,et al. Immunoglobulin expression and the humoral immune response is regulated by the non-canonical poly(A) polymerase TENT5C , 2020, Nature Communications.
[8] D. O’Carroll,et al. Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia , 2019, Cell stem cell.
[9] Annalisa Marsico,et al. PureCLIP: capturing target-specific protein–RNA interaction footprints from single-nucleotide CLIP-seq data , 2017, Genome Biology.
[10] Anton J. Enright,et al. The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence , 2017, Molecular cell.
[11] D. Nowis,et al. The non-canonical poly(A) polymerase FAM46C acts as an onco-suppressor in multiple myeloma , 2017, Nature Communications.
[12] Neville E Sanjana,et al. Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening , 2016, Nature Protocols.
[13] Simone Sidoli,et al. High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells. , 2016, Molecular cell.
[14] K. Rajewsky,et al. Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line , 2016, Proceedings of the National Academy of Sciences.
[15] W. Gilbert,et al. Mutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegans , 2016, PLoS genetics.
[16] Ligang Wu,et al. YTHDF2 destabilizes m6A-containing RNA through direct recruitment of the CCR4–NOT deadenylase complex , 2016, Nature Communications.
[17] M. Hentze,et al. Identification of RNA-binding Proteins in Macrophages by Interactome Capture* , 2016, Molecular & Cellular Proteomics.
[18] Fidel Ramírez,et al. deepTools2: a next generation web server for deep-sequencing data analysis , 2016, Nucleic Acids Res..
[19] P. Shankar,et al. Optimizing sgRNA structure to improve CRISPR-Cas9 knockout efficiency , 2015, Genome Biology.
[20] Jeroen Krijgsveld,et al. The RNA-binding proteomes from yeast to man harbour conserved enigmRBPs , 2015, Nature Communications.
[21] Arne Klungland,et al. A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation , 2015, Genes & development.
[22] H. Jäck,et al. miR‐148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2 , 2015, European journal of immunology.
[23] A. Rao,et al. RNA-binding protein hnRNPLL regulates mRNA splicing and stability during B-cell to plasma-cell differentiation , 2015, Proceedings of the National Academy of Sciences.
[24] Steven L Salzberg,et al. HISAT: a fast spliced aligner with low memory requirements , 2015, Nature Methods.
[25] Hakho Lee,et al. Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis , 2015, Cell.
[26] Philip D. Hodgkin,et al. The generation of antibody-secreting plasma cells , 2015, Nature Reviews Immunology.
[27] Jun S. Liu,et al. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens , 2014, Genome Biology.
[28] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[29] S. Gerstberger,et al. A census of human RNA-binding proteins , 2014, Nature Reviews Genetics.
[30] C. Abreu-Goodger,et al. The miR-155–PU.1 axis acts on Pax5 to enable efficient terminal B cell differentiation , 2014, The Journal of experimental medicine.
[31] Wei Shi,et al. The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation , 2014, The Journal of experimental medicine.
[32] Robert Langer,et al. CRISPR-Cas9 Knockin Mice for Genome Editing and Cancer Modeling , 2014, Cell.
[33] E. Izaurralde,et al. A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing. , 2014, Molecular cell.
[34] Jeroen Krijgsveld,et al. The RNA-binding protein repertoire of embryonic stem cells , 2013, Nature Structural &Molecular Biology.
[35] U. Klein,et al. Article Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of Irf4 , 2022 .
[36] P. Blackshear,et al. Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by Tristetraprolin , 2013, Nature Structural &Molecular Biology.
[37] O. Elemento,et al. Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons , 2012, Cell.
[38] Richard Bonneau,et al. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. , 2012, Molecular cell.
[39] Norman E. Davey,et al. Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins , 2012, Cell.
[40] M. Kupiec,et al. Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq , 2012, Nature.
[41] D. Kitamura,et al. In-vitro derived germinal centre B cells differentially generate memory B or plasma cells in vivo. , 2011, Nature communications.
[42] Peter J. Bickel,et al. Measuring reproducibility of high-throughput experiments , 2011, 1110.4705.
[43] K. Calame,et al. Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch , 2010, The EMBO journal.
[44] Sabyasachi Das,et al. MicroRNA 125b inhibition of B cell differentiation in germinal centers. , 2010, International immunology.
[45] Cole Trapnell,et al. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome , 2009, Genome Biology.
[46] Kyoko Ochiai,et al. Regulation of the plasma cell transcription factor Blimp-1 gene by Bach2 and Bcl6. , 2008, International immunology.
[47] Tetsuo Noda,et al. Plasmacytic Transcription Factor Blimp-1 Is Repressed by Bach2 in B Cells* , 2006, Journal of Biological Chemistry.
[48] M. Reth,et al. Testing gene function early in the B cell lineage in mb1-cre mice , 2006, Proceedings of the National Academy of Sciences.
[49] Roger Sciammas,et al. Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. , 2006, Immunity.
[50] L. Staudt,et al. Direct Repression of prdm1 by Bcl-6 Inhibits Plasmacytic Differentiation1 , 2004, The Journal of Immunology.
[51] K. Calame,et al. Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. , 2003, Immunity.
[52] Kuo-I Lin,et al. Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells , 2002, Molecular and Cellular Biology.
[53] Liming Yang,et al. Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. , 2002, Immunity.
[54] L. Staudt,et al. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. , 2000, Immunity.
[55] R. Jackson,et al. unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA. , 1999, Genes & development.
[56] Klaus Rajewsky,et al. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene , 1991, Nature.