Ability of heart rate variability to predict prognosis in patients with advanced congestive heart failure.

We analyzed heart rate variability from normal RR intervals in patients with advanced congestive heart failure. Although most patients had decreased HRV, patients with a life-threatening cardiac event or death (n = 8) within 18 months had significantly lower heart rate variability than those who did not (n = 18), which may have value in determining prognosis in this population.

[1]  J. Miller,et al.  Decreased heart rate variability and its association with increased mortality after acute myocardial infarction. , 1987, The American journal of cardiology.

[2]  G. PORENTA,et al.  Prognostic Value of Heart Rate Variability in Patients Awaiting Cardiac Transplantation , 1992, Pacing and clinical electrophysiology : PACE.

[3]  D. Levy,et al.  Impact of reduced heart rate variability on risk for cardiac events. The Framingham Heart Study. , 1996, Circulation.

[4]  A. Maggioni,et al.  Prognostic significance of heart rate variability in post-myocardial infarction patients in the fibrinolytic era. The GISSI-2 results. Gruppo Italiano per lo Studio della Sopravvivenza nell' Infarto Miocardico. , 1996, Circulation.

[5]  J. A. Thomas,et al.  Plasma norepinephrine in congestive heart failure. , 1978, The American journal of cardiology.

[6]  P. Stein,et al.  Time domain measurements of heart rate variability. , 1992, Cardiology clinics.

[7]  P. Binkley,et al.  Role of spectral measures of heart rate variability as markers of disease progression in patients with chronic congestive heart failure not treated with angiotensin-converting enzyme inhibitors. , 1996, American heart journal.

[8]  R. Coleman,et al.  Relative importance of electrode placement over number of channels in transient myocardial ischemia detection by Holter monitoring. , 1995, The American journal of cardiology.

[9]  P. Stein,et al.  Heart rate variability: a measure of cardiac autonomic tone. , 1994, American heart journal.

[10]  P. Binkley,et al.  Assessment of autonomic tone over a 24-hour period in patients with congestive heart failure: relation between mean heart rate and measures of heart rate variability. , 1995, American heart journal.

[11]  G. Casolo,et al.  Decreased spontaneous heart rate variability in congestive heart failure. , 1989, The American journal of cardiology.

[12]  M. Packer Modulation of functional capacity and survival in congestive heart failure. Effects of activation of the sympathetic nervous system. , 1988, Postgraduate medicine.

[13]  J. Cohn,et al.  Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. , 1984, The New England journal of medicine.

[14]  P. Stein,et al.  Stability of index of heart rate variability in patients with congestive heart failure. , 1995, American heart journal.

[15]  J. Cohn,et al.  Response of plasma norepinephrine and epinephrine to dynamic exercise in patients with congestive heart failure. , 1982, The American journal of cardiology.

[16]  A. Timmis,et al.  Relation between heart rate variability early after acute myocardial infarction and long-term mortality. , 1994, The American journal of cardiology.