Naturalistic assessment of everyday functioning in individuals with mild cognitive impairment: the day-out task.

OBJECTIVE The day-out task (DOT), a naturalistic task that requires multitasking in a real-world setting, was used to examine everyday functioning in individuals with mild cognitive impairment (MCI). METHOD Thirty-eight participants with MCI and 38 cognitively healthy older adult controls prioritized, organized, initiated, and completed a number of subtasks in a campus apartment to prepare for a day out (e.g., determine and gather change for bus, bring a magazine). Participants also completed tests assessing cognitive constructs important in multitasking (i.e., retrospective memory, prospective memory, planning). RESULTS As compared with controls, the MCI group required more time to complete the DOT and demonstrated poorer task accuracy, performing more subtasks incompletely and inaccurately. Despite poorer DOT task accuracy, the MCI and control groups approached completion of the DOT in a similar manner. For the MCI group, retrospective memory was a unique predictor of the number of subtasks left incomplete and inaccurate, while prospective memory was a unique predictor of DOT sequencing. The DOT measures, but not the cognitive tests, were predictive of knowledgeable informant report of everyday functioning. CONCLUSIONS THESE findings suggest that difficulty remembering and keeping track of multiple goals and subgoals may contribute to the poorer performance of individuals with MCI in complex everyday situations.

[1]  Maureen Schmitter-Edgecombe,et al.  Cognitive Correlates of Functional Performance in Older Adults: Comparison of Self-Report, Direct Observation, and Performance-Based Measures , 2011, Journal of the International Neuropsychological Society.

[2]  T. Shallice,et al.  Deficits in strategy application following frontal lobe damage in man. , 1991, Brain : a journal of neurology.

[3]  W. Jagust,et al.  Degree of discrepancy between self and other‐reported everyday functioning by cognitive status: dementia, mild cognitive impairment, and healthy elders , 2005, International journal of geriatric psychiatry.

[4]  C. Cook An Exploration of the Neural Control of Multitasking and the Implications for Practice , 2008 .

[5]  Marshal F. Folstein,et al.  The telephone interview for cognitive status , 1988 .

[6]  R. Petersen,et al.  Mild cognitive impairment , 2006, The Lancet.

[7]  Evelyne Klinger,et al.  Use of the Virtual Action Planning Supermarket for the Diagnosis of Mild Cognitive Impairment , 2009, Dementia and Geriatric Cognitive Disorders.

[8]  M. Trabucchi,et al.  Conversion of amnestic Mild Cognitive Impairment to dementia of Alzheimer type is independent to memory deterioration , 2007, International journal of geriatric psychiatry.

[9]  Michael Marsiske,et al.  The Revised Observed Tasks of Daily Living: A Performance-Based Assessment of Everyday Problem Solving in Older Adults , 2005, Journal of applied gerontology : the official journal of the Southern Gerontological Society.

[10]  A. Drewnowski,et al.  Journals of Gerontology , 2001 .

[11]  R. R. Abidin Psychological Assessment Resources , 1995 .

[12]  P J Nichols,et al.  Functional Assessment , 2019, The SAGE Encyclopedia of Human Communication Sciences and Disorders.

[13]  Lars Bäckman,et al.  Patterns of prospective and retrospective memory impairment in preclinical Alzheimer's disease. , 2006, Neuropsychology.

[14]  Jason C. Allaire,et al.  Mild Cognitive Impairment and Objective Instrumental Everyday Functioning: The Everyday Cognition Battery Memory Test , 2009, Journal of the American Geriatrics Society.

[15]  Robert H. Logie,et al.  Multitasking, working memory and remembering intentions , 2010 .

[16]  Sarah Tomaszewski Farias,et al.  The relationship between neuropsychological performance and daily functioning in individuals with Alzheimer's disease: ecological validity of neuropsychological tests. , 2003, Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists.

[17]  L. Nilsson,et al.  Executive Functioning in Older Adults with Mild Cognitive Impairment: MCI Has Effects on Planning, But Not on Inhibition , 2007, Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition.

[18]  Janet B W Williams,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[19]  D. G. Clark,et al.  Declining financial capacity in mild cognitive impairment , 2009, Neurology.

[20]  Thomas D. Marcotte,et al.  Neuropsychology of everyday functioning , 2010 .

[21]  Holly Tuokko,et al.  Mild cognitive impairment and everyday functioning in older adults , 2005, Neurocase.

[22]  J. Morris,et al.  Current concepts in mild cognitive impairment. , 2001, Archives of neurology.

[23]  C. Jack,et al.  Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment , 2004, Journal of internal medicine.

[24]  P. Burgess,et al.  The case for the development and use of “ecologically valid” measures of executive function in experimental and clinical neuropsychology , 2006, Journal of the International Neuropsychological Society.

[25]  J. Morris,et al.  Mild cognitive impairment as a clinical entity and treatment target. , 2005, Archives of neurology.

[26]  P. Rabbitt,et al.  Methodology of Frontal and Executive Function , 1999 .

[27]  Tania Giovannetti,et al.  Characterization of Everyday Functioning in Mild Cognitive Impairment: A Direct Assessment Approach , 2008, Dementia and Geriatric Cognitive Disorders.

[28]  Paul W. Burgess,et al.  Theory and methodology in executive function research , 1997 .

[29]  T. L. Brink,et al.  Clinical Gerontology: A Guide to Assessment and Intervention , 1986 .

[30]  J. Becker,et al.  Ecological assessment of executive functions in mild cognitive impairment and mild Alzheimer’s disease , 2009, Journal of the International Neuropsychological Society.

[31]  Robert K. Heaton,et al.  Neuropsychology and the prediction of everyday functioning. , 2010 .

[32]  P. Burgess,et al.  The ecological validity of tests of executive function , 1998, Journal of the International Neuropsychological Society.

[33]  Nick C Fox,et al.  The Diagnosis of Mild Cognitive Impairment due to Alzheimer’s Disease: Recommendations from the National Institute on Aging-Alzheimer’s Association Workgroups on Diagnostic Guidelines for Alzheimer’s Disease , 2011 .

[34]  P J Holliday,et al.  Functional performance measures: are they superior to self-assessments? , 1993, Journal of gerontology.

[35]  Impaired financial abilities in mild cognitive impairment , 2003, Neurology.

[36]  K. Coburn,et al.  The cognitive correlates of functional status , 2007 .

[37]  Maureen Schmitter-Edgecombe,et al.  Improving the ecological validity of executive functioning assessment. , 2006, Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists.

[38]  Kathleen A. Welsh-Bohmer,et al.  Geriatric neuropsychology : assessment and intervention , 2006 .

[39]  J. Morris,et al.  The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease , 2011, Alzheimer's & Dementia.

[40]  M. Schmitter-Edgecombe,et al.  Characterizing multiple memory deficits and their relation to everyday functioning in individuals with mild cognitive impairment. , 2009, Neuropsychology.

[41]  S. Zimmerman,et al.  Methodological issues in measuring the functional status of cognitively impaired nursing home residents: the use of proxies and performance-based measures. , 1994, Alzheimer Disease and Associated Disorders.

[42]  Oscar L. Lopez,et al.  Telephone Interview for Cognitive Status , 2009, Neuroepidemiology.

[43]  S. Willis,et al.  Everyday problem solving in Alzheimer's patients: A comparison of subjective and objective assessments , 1999 .

[44]  Y. Stern,et al.  Functional deficits in patients with mild cognitive impairment: Prediction of AD , 2002, Neurology.

[45]  B. Lawlor,et al.  Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer’s disease etiology using a novel event-based prospective memory task , 2009, Journal of the International Neuropsychological Society.

[46]  N. Foster,et al.  Mild cognitive impairments predict dementia in nondemented elderly patients with memory loss. , 2001, Archives of neurology.

[47]  V. Bowden,et al.  The Journal of Neuropsychiatry and Clinical Neurosciences , 1992 .

[48]  O. Okonkwo,et al.  Mild Cognitive Impairment and Everyday Function: An Investigation of Driving Performance , 2009, Journal of geriatric psychiatry and neurology.

[49]  J. Yesavage,et al.  Geriatric Depression Scale (GDS): Recent evidence and development of a shorter version. , 1986 .

[50]  C. P. Hughes,et al.  A New Clinical Scale for the Staging of Dementia , 1982, British Journal of Psychiatry.

[51]  J. Morris The Clinical Dementia Rating (CDR) , 1993, Neurology.

[52]  Robert J. Sbordone,et al.  Ecological Validity of Neuropsychological Testing , 1996 .

[53]  Michael J Cortese,et al.  Prospective memory and apolipoprotein E in healthy aging and early stage Alzheimer's disease. , 2006, Neuropsychology.

[54]  Frederick A Schmitt,et al.  The impact of caregiver executive skills on reports of patient functioning. , 2008, The Gerontologist.

[55]  Kevin J Black,et al.  The cognitive correlates of functional status: a review from the Committee on Research of the American Neuropsychiatric Association. , 2007, The Journal of neuropsychiatry and clinical neurosciences.

[56]  M. Weiner,et al.  Performance-Based instrument to assess functional capacity in dementia: The Texas Functional Living Scale. , 2001, Neuropsychiatry, neuropsychology, and behavioral neurology.

[57]  E. Richardson,et al.  Neuropsychologic Prediction of Performance Measures of Daily Living Skills in Geriatric Patients , 1995 .

[58]  松本 哲夫,et al.  皮質下梗塞患者における遂行機能障害に関する研究 : Behavioural Assessment of the Dysexecutive Syndromeを用いた検討 , 2008 .

[59]  L. Harrell,et al.  Impaired financial abilities in mild cognitive impairment , 2003, Neurology.

[60]  T. Shallice,et al.  The cognitive and neuroanatomical correlates of multitasking , 2000, Neuropsychologia.

[61]  Giuseppe Zappalà,et al.  The mini‐mental state examination: Normative study of an Italian random sample , 1993 .

[62]  P W Burgess,et al.  Strategy application disorder: the role of the frontal lobes in human multitasking , 2000, Psychological research.