The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.

[1]  David Bryder,et al.  Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. , 2006, The American journal of pathology.

[2]  K. Ottersbach,et al.  The Endothelium: The Cradle of Definitive Hematopoiesis? , 2006 .

[3]  Elaine Dzierzak,et al.  GATA-2 Plays Two Functionally Distinct Roles during the Ontogeny of Hematopoietic Stem Cells , 2004, The Journal of experimental medicine.

[4]  Bing Liu,et al.  Human placenta-derived mesenchymal progenitor cells support culture expansion of long-term culture-initiating cells from cord blood CD34+ cells. , 2004, Experimental hematology.

[5]  M. Alvarez-Silva,et al.  Mouse placenta is a major hematopoietic organ , 2003, Development.

[6]  J. Cross,et al.  Chorioallantoic Morphogenesis and Formation of the Placental Villous Tree , 2003, Annals of the New York Academy of Sciences.

[7]  J. Kingdom,et al.  Genes, development and evolution of the placenta. , 2003, Placenta.

[8]  S. Orkin,et al.  Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo. , 2003, Blood.

[9]  Elaine Dzierzak,et al.  The Ly‐6A (Sca‐1) GFP Transgene is Expressed in all Adult Mouse Hematopoietic Stem Cells , 2002, Stem cells.

[10]  A. M. Morrison,et al.  Quantitative developmental anatomy of definitive haematopoietic stem cells/long-term repopulating units (HSC/RUs): role of the aorta-gonad-mesonephros (AGM) region and the yolk sac in colonisation of the mouse embryonic liver. , 2002, Development.

[11]  K. Ottersbach,et al.  Hematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta. , 2002, Immunity.

[12]  Elaine Dzierzak,et al.  Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. , 2002, Immunity.

[13]  M. D. de Bruijn,et al.  Isolation and analysis of hematopoietic stem cells from mouse embryos. , 2002, Methods in molecular medicine.

[14]  S. Nishikawa.  A complex linkage in the developmental pathway of endothelial and hematopoietic cells. , 2001, Current opinion in cell biology.

[15]  V. Han,et al.  Control of growth and development of the feto-placental unit. , 2001, Current opinion in pharmacology.

[16]  A. Cumano,et al.  Intraembryonic, but not yolk sac hematopoietic precursors, isolated before circulation, provide long-term multilineage reconstitution. , 2001, Immunity.

[17]  J. Rossant,et al.  Placental development: Lessons from mouse mutants , 2001, Nature Reviews Genetics.

[18]  J. Downing,et al.  Haploinsufficiency of AML1 affects the temporal and spatial generation of hematopoietic stem cells in the mouse embryo. , 2000, Immunity.

[19]  A. Ciau-Uitz,et al.  Distinct Origins of Adult and Embryonic Blood in Xenopus , 2000, Cell.

[20]  N. Speck,et al.  Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo , 2000, The EMBO journal.

[21]  I. Weissman,et al.  The monoclonal antibody TER‐119 recognizes a molecule associated with glycophorin A and specifically marks the late stages of murine erythroid lineage , 2000, British journal of haematology.

[22]  J. D. Engel,et al.  The mouse GATA-2 gene is expressed in the para-aortic splanchnopleura and aorta-gonads and mesonephros region. , 1999, Blood.

[23]  Chris I. De Zeeuw,et al.  GATA-3 Is Involved in the Development of Serotonergic Neurons in the Caudal Raphe Nuclei , 1999, The Journal of Neuroscience.

[24]  T. Gu,et al.  Cbfa2 is required for the formation of intra-aortic hematopoietic clusters. , 1999, Development.

[25]  J. D. Engel,et al.  Rescue of the embryonic lethal hematopoietic defect reveals a critical role for GATA‐2 in urogenital development , 1998, The EMBO journal.

[26]  R. Gardner,et al.  Vascularization in the murine allantois occurs by vasculogenesis without accompanying erythropoiesis. , 1998, Development.

[27]  F. Dieterlen-Lièvre.  Hematopoiesis: Progenitors and their genetic program , 1998, Current Biology.

[28]  J. Cross.  Formation of the Placenta and Extraembryonic Membranes , 1998, Annals of the New York Academy of Sciences.

[29]  F. Dieterlen‐Lièvre,et al.  Blood-borne seeding by hematopoietic and endothelial precursors from the allantois. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[30]  D. Bodine,et al.  Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. , 1997, Immunity.

[31]  K. Downs,et al.  Developmental potency of the murine allantois. , 1997, Development.

[32]  M. Yoder,et al.  In vivo repopulating hematopoietic stem cells are present in the murine yolk sac at day 9.0 postcoitus. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[33]  I. Weissman,et al.  Identification of a lineage of multipotent hematopoietic progenitors. , 1997, Development.

[34]  J. D. Engel,et al.  GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. , 1997, Development.

[35]  E. Dzierzak,et al.  Characterization of the first definitive hematopoietic stem cells in the AGM and liver of the mouse embryo. , 1996, Immunity.

[36]  A. Medvinsky,et al.  Definitive Hematopoiesis Is Autonomously Initiated by the AGM Region , 1996, Cell.

[37]  M. Marín‐Padilla,et al.  Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[38]  J. Downing,et al.  AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis , 1996, Cell.

[39]  James Douglas Engel,et al.  Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haematopoiesis , 1995, Nature Genetics.

[40]  J. B. Turpen,et al.  Intraembryonic origin of hepatic hematopoiesis in Xenopus laevis. , 1995, Journal of immunology.

[41]  J. D. Engel,et al.  GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene. , 1994, Development.

[42]  Stuart H. Orkin,et al.  An early haematopoietic defect in mice lacking the transcription factor GATA-2 , 1994, Nature.

[43]  J. Strouboulis,et al.  Development of hematopoietic stem cell activity in the mouse embryo. , 1994, Immunity.

[44]  B. Spiegelman,et al.  Pleiotropic effects of a null mutation in the c-fos proto-oncogene , 1992, Cell.

[45]  J. Strouboulis,et al.  Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice. , 1992, Genes & development.

[46]  K. Mizuno,et al.  Monoclonal Antibody , 2020, Definitions.

[47]  D. Chui,et al.  Hemopoietic stem cells in murine embryonic yolk sac and peripheral blood. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[48]  I. Verma,et al.  Expression of c‐onc genes: c‐fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion. , 1983, The EMBO journal.

[49]  A. Burgess,et al.  Stimulation by human placental conditioned medium of hemopoietic colony formation by human marrow cells. , 1977, Blood.

[50]  F. Dieterlen-Lièvre,et al.  On the origin of haemopoietic stem cells in the avian embryo: an experimental approach. , 1975, Journal of embryology and experimental morphology.

[51]  M. Moore,et al.  Ontogeny of the Haemopoietic System: Yolk Sac Origin of In Vivo and In Vitro Colony Forming Cells in the Developing Mouse Embryo * , 1970, British journal of haematology.