Structure and dimerization of the kinase domain from yeast Snf1, a member of the Snf1/AMPK protein family.

[1]  S. Berger,et al.  Histone H3 phosphorylation can promote TBP recruitment through distinct promoter‐specific mechanisms , 2005, The EMBO journal.

[2]  J. Clapham.  Treating obesity: pharmacology of energy expenditure. , 2004, Current drug targets.

[3]  L. Johnson,et al.  Protein Kinase Inhibitors: Insights into Drug Design from Structure , 2004, Science.

[4]  M. Paul,et al.  Highly conserved protein kinases involved in the regulation of carbon and amino acid metabolism. , 2003, Journal of experimental botany.

[5]  David Carling,et al.  The AMP-activated protein kinase cascade--a unifying system for energy control. , 2004, Trends in biochemical sciences.

[6]  David Carling,et al.  Supplemental Data LKB 1 Is the Upstream Kinase in the AMP-Activated Protein Kinase Cascade , 2003 .

[7]  P. Sanz.  Snf1 protein kinase: a key player in the response to cellular stress in yeast. , 2001, Biochemical Society transactions.

[8]  R. McCartney,et al.  Purification and Characterization of Snf1 Kinase Complexes Containing a Defined β Subunit Composition* , 2002, The Journal of Biological Chemistry.

[9]  J. Kuriyan,et al.  The Conformational Plasticity of Protein Kinases , 2002, Cell.

[10]  J. Seidman,et al.  Constitutively active AMP kinase mutations cause glycogen storage disease mimicking hypertrophic cardiomyopathy. , 2002, The Journal of clinical investigation.

[11]  Young-Bum Kim,et al.  Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase , 2002, Nature.

[12]  Maria Carla Parrini,et al.  Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1. , 2002, Molecular cell.

[13]  Margaret S. Wu,et al.  Role of AMP-activated protein kinase in mechanism of metformin action. , 2001, The Journal of clinical investigation.

[14]  R. McCartney,et al.  Regulation of Snf1 Kinase , 2001, The Journal of Biological Chemistry.

[15]  S. Berger,et al.  Snf1--a Histone Kinase That Works in Concert with the Histone Acetyltransferase Gcn5 to Regulate Transcription , 2001, Science.

[16]  M. Carlson,et al.  Subcellular localization of the Snf1 kinase is regulated by specific beta subunits and a novel glucose signaling mechanism. , 2001, Genes & development.

[17]  P. Grant,et al.  A tale of histone modifications , 2001, Genome Biology.

[18]  H. Schüller,et al.  Contribution of Cat8 and Sip4 to the transcriptional activation of yeast gluconeogenic genes by carbon source-responsive elements , 2001, Current Genetics.

[19]  D. W. Abbott,et al.  Histone variants and histone modifications: a structural perspective. , 2001, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[20]  R. McCartney,et al.  β‐subunits of Snf1 kinase are required for kinase function and substrate definition , 2000, The EMBO journal.

[21]  M. Carlson,et al.  A regulatory shortcut between the Snf1 protein kinase and RNA polymerase II holoenzyme. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[22]  C. Allis,et al.  The language of covalent histone modifications , 2000, Nature.

[23]  L. Johnson,et al.  The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases , 1999, Nature Cell Biology.

[24]  N. Pavletich.  Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. , 1999, Journal of molecular biology.

[25]  M. Carlson,et al.  Snf1 Protein Kinase Regulates Phosphorylation of the Mig1 Repressor in Saccharomyces cerevisiae , 1998, Molecular and Cellular Biology.

[26]  M. Carlson,et al.  The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? , 1998, Annual review of biochemistry.

[27]  M. Carlson,et al.  The Snf1 protein kinase and its activating subunit, Snf4, interact with distinct domains of the Sip1/Sip2/Gal83 component in the kinase complex , 1997, Molecular and cellular biology.

[28]  S. Doublié.  [29] Preparation of selenomethionyl proteins for phase determination. , 1997, Methods in enzymology.

[29]  M. Carlson,et al.  Glucose regulates protein interactions within the yeast SNF1 protein kinase complex. , 1996, Genes & development.

[30]  Kornelia Polyak,et al.  Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex , 1995, Nature.

[31]  M. Carlson,et al.  A family of proteins containing a conserved domain that mediates interaction with the yeast SNF1 protein kinase complex. , 1994, The EMBO journal.

[32]  M. Lawrence,et al.  Shape complementarity at protein/protein interfaces. , 1993, Journal of molecular biology.

[33]  Sung-Hou Kim,et al.  Crystal structure of cyclin-dependent kinase 2 , 1993, Nature.

[34]  J. Zheng,et al.  Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase. , 1991, Science.