Association between the germline MC1R variants and somatic BRAF/NRAS mutations in melanoma tumors.

[1]  C. Begg,et al.  Relationship between germline MC1R variants and BRAF-mutant melanoma in a North Carolina population-based study. , 2010, The Journal of investigative dermatology.

[2]  D. Schadendorf,et al.  Melanocortin receptor 1 variants and melanoma risk: A study of 2 European populations , 2009, International journal of cancer.

[3]  M. Mazumdar,et al.  Changes in the presentation of nodular and superficial spreading melanomas over 35 years , 2008, Cancer.

[4]  D. Elder,et al.  MC1R variants increase risk of melanomas harboring BRAF mutations. , 2008, The Journal of investigative dermatology.

[5]  D. Peeper,et al.  BRAFE600 in benign and malignant human tumours , 2008, Oncogene.

[6]  Snæbjörn Pálsson,et al.  Genetic determinants of hair, eye and skin pigmentation in Europeans , 2007, Nature Genetics.

[7]  N. Dhomen,et al.  New insight into BRAF mutations in cancer. , 2007, Current opinion in genetics & development.

[8]  R. Spang,et al.  Gene Expression Signatures for Tumor Progression, Tumor Subtype, and Tumor Thickness in Laser-Microdissected Melanoma Tissues , 2007, Clinical Cancer Research.

[9]  D. Pinkel,et al.  MC1R Germline Variants Confer Risk for BRAF-Mutant Melanoma , 2006, Science.

[10]  J. García-Borrón,et al.  Melanocortin-1 receptor structure and functional regulation. , 2005, Pigment cell research.

[11]  J. Rees Genetics of hair and skin color. , 2003, Annual review of genetics.

[12]  D. Duffy,et al.  MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations. , 2001, American journal of human genetics.

[13]  N. Hayward,et al.  The association between MC1R genotype and BRAF mutation status in cutaneous melanoma: findings from an Australian population. , 2010, The Journal of investigative dermatology.

[14]  M. Gordon In Melanoma, RAS Mutations Are Accompanied by Switching Signaling from BRAF to CRAF and Disrupted Cyclic AMP Signaling , 2008 .