Oct4 reduction contributes to testicular injury of unilateral testicular torsion in mice model and apoptotic death of Sertoli cells through mediating CIP2A expression.

[1]  H. A. Nahas,et al.  Vitamin D3 Prevents the Deleterious Effects of Testicular Torsion on Testis by Targeting miRNA-145 and ADAM17: In Silico and In Vivo Study , 2021, Pharmaceuticals.

[2]  Lv Wang,et al.  OCT4 Represses Inflammation and Cell Injury During Orchitis by Regulating CIP2A Expression , 2021, Frontiers in Cell and Developmental Biology.

[3]  M. Refat,et al.  New Mononuclear and Binuclear Cu(II), Co(II), Ni(II), and Zn(II) Thiosemicarbazone Complexes with Potential Biological Activity: Antimicrobial and Molecular Docking Study , 2021, Molecules.

[4]  O. Koca,et al.  Protective Effect of Udenafil Against Ischemia Reperfusion Injury Due to Testicular Torsion/Detorsion in Rat Model. , 2020, The Eurasian journal of medicine.

[5]  S. Phillips,et al.  Vitamin D Improves Nitric Oxide-Dependent Vasodilation in Adipose Tissue Arterioles from Bariatric Surgery Patients , 2019, Nutrients.

[6]  M. Steinfath,et al.  Remote ischemic preconditioning attenuates intestinal mucosal damage: insight from a rat model of ischemia–reperfusion injury , 2019, Journal of Translational Medicine.

[7]  D. Ohl,et al.  The Impact of Testicular Torsion on Testicular Function , 2019, The world journal of men's health.

[8]  S. Miriuka,et al.  Superoxide dismutase 1 expression is modulated by the core pluripotency transcription factors Oct4, Sox2 and Nanog in embryonic stem cells , 2018, Mechanisms of Development.

[9]  F. Schneck,et al.  Direction of Rotation in Testicular Torsion and Identification of Predictors of Testicular Salvage. , 2017, Urology.

[10]  Matthew S. Cook,et al.  Chemotherapy-Induced Depletion of OCT4-Positive Cancer Stem Cells in a Mouse Model of Malignant Testicular Cancer. , 2017, Cell reports.

[11]  B. Zirkin,et al.  Steroidogenesis in Leydig cells: effects of aging and environmental factors. , 2017, Reproduction.

[12]  Si-Ming Wei,et al.  Probucol Reduces Testicular Torsion/Detorsion-Induced Ischemia/Reperfusion Injury in Rats , 2017, Oxidative medicine and cellular longevity.

[13]  Woo-Jin Song,et al.  Anti-inflammatory Effects of Oct4/Sox2-overexpressing Human Adipose Tissue-derived Mesenchymal Stem Cells. , 2017, In vivo.

[14]  M. Montes-Bayón,et al.  Elemental labelling and mass spectrometry for the specific detection of sulfenic acid groups in model peptides: a proof of concept , 2017, Analytical and Bioanalytical Chemistry.

[15]  Dimphy Zeegers,et al.  Distribution pattern of cytoplasmic organelles, spindle integrity, oxidative stress, octamer-binding transcription factor 4 (Oct4) expression and developmental potential of oocytes following multiple superovulation. , 2016, Reproduction, fertility, and development.

[16]  A. Bitto,et al.  ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury , 2016, Oxidative medicine and cellular longevity.

[17]  H. Oguzturk,et al.  Protective effects of hesperidin in experimental testicular ischemia/reperfusion injury in rats , 2015, Archives of medical science : AMS.

[18]  T. Paavonen,et al.  The association and prognostic relevance of cancerous inhibitor of protein phosphatase 2A and inflammation in tongue squamous cell carcinoma , 2015, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[19]  J. Toppari,et al.  CIP2A is an Oct4 target gene involved in head and neck squamous cell cancer oncogenicity and radioresistance , 2014, Oncotarget.

[20]  Kuen-Feng Chen,et al.  TD-19, an Erlotinib Derivative, Induces Epidermal Growth Factor Receptor Wild-Type Nonsmall-Cell Lung Cancer Apoptosis through CIP2A-Mediated Pathway , 2014, The Journal of Pharmacology and Experimental Therapeutics.

[21]  S. Hucumenoglu,et al.  The effect of sildenafil and udenafil on testicular damage following ischemia-reperfusion injury in rats. , 2014, The Journal of urology.

[22]  Guoyang Huang,et al.  Nrf2 activation in astrocytes contributes to spinal cord ischemic tolerance induced by hyperbaric oxygen preconditioning. , 2014, Journal of neurotrauma.

[23]  A. Patel,et al.  Oxidative stress and antioxidants in disease and cancer: a review. , 2014, Asian Pacific journal of cancer prevention : APJCP.

[24]  F. Sampaio,et al.  Effect of antioxidants on outcome of testicular torsion in rats of different ages. , 2014, The Journal of urology.

[25]  Liangfang Shen,et al.  High Expression of SOX2 and OCT4 Indicates Radiation Resistance and an Independent Negative Prognosis in Cervical Squamous Cell Carcinoma , 2014, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[26]  E. Akbay,et al.  Rho-kinase levels in testicular ischemia-reperfusion injury and effects of its inhibitor, Y-27632, on oxidative stress, spermatogenesis, and apoptosis. , 2014, Urology.

[27]  Wenwu Liu,et al.  Lactulose ameliorates cerebral ischemia-reperfusion injury in rats by inducing hydrogen by activating Nrf2 expression. , 2013, Free radical biology & medicine.

[28]  J. Westermarck,et al.  Cancerous inhibitor of protein phosphatase 2A, an emerging human oncoprotein and a potential cancer therapy target. , 2013, Cancer research.

[29]  Christina Wang,et al.  Integrity of the blood-testis barrier in healthy men after suppression of spermatogenesis with testosterone and levonorgestrel. , 2012, Human reproduction.

[30]  A. D. Ikebuaso,et al.  Experimental Testicular Torsion in a Rat Model: Effects of Treatment with Pausinystalia macroceras on Testis Functions , 2012, Journal of reproduction & infertility.

[31]  Q. Ma,et al.  Molecular Basis of Electrophilic and Oxidative Defense: Promises and Perils of Nrf2 , 2012, Pharmacological Reviews.

[32]  D. Sheriff,et al.  Testicular Torsion-Detorsion- Histological and Biochemical Changes in Rat Testis , 2012 .

[33]  E. Bae,et al.  CIP2A expression is associated with synovial hyperplasia and invasive function of fibroblast-like synoviocytes in rheumatoid arthritis , 2012, Rheumatology International.

[34]  Y. Toiyama,et al.  CD133, OCT4, and NANOG in ulcerative colitis-associated colorectal cancer. , 2011, Oncology letters.

[35]  C. Haglund,et al.  Prognostic role of CIP2A expression in serous ovarian cancer , 2011, British Journal of Cancer.

[36]  M. Chou,et al.  Markedly increased Oct4 and Nanog expression correlates with cisplatin resistance in oral squamous cell carcinoma. , 2011, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.

[37]  Xinjun Dong,et al.  CIP2A is Overexpressed in Non-Small Cell Lung Cancer and Correlates with Poor Prognosis , 2011, Annals of Surgical Oncology.

[38]  Donna D. Zhang.  The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer. , 2010, Antioxidants & redox signaling.

[39]  G. Evan,et al.  MYC-dependent regulation and prognostic role of CIP2A in gastric cancer. , 2009, Journal of the National Cancer Institute.

[40]  Hiroshi Handa,et al.  A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress. , 2009, Genes & development.

[41]  R. Sears,et al.  CIP2A Inhibits PP2A in Human Malignancies , 2007, Cell.

[42]  M. Srougi,et al.  Late hormonal levels, semen parameters, and presence of antisperm antibodies in patients treated for testicular torsion. , 2007, Journal of andrology.

[43]  R. Montironi,et al.  OCT4: biological functions and clinical applications as a marker of germ cell neoplasia , 2007, The Journal of pathology.

[44]  A. Avcı,et al.  Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion , 2006, Scandinavian journal of urology and nephrology.

[45]  Liang Cheng,et al.  OCT4 Staining in Testicular Tumors: A Sensitive and Specific Marker for Seminoma and Embryonal Carcinoma , 2004, The American journal of surgical pathology.

[46]  H. Niwa,et al.  Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. , 2002, Nucleic acids research.

[47]  H. Schöler,et al.  Oct4 distribution and level in mouse clones: consequences for pluripotency. , 2002, Genes & development.

[48]  L. Looijenga,et al.  Expression of the PDGF α‐receptor 1.5 kb transcript, OCT‐4, and c‐KIT in human normal and malignant tissues. Implications for the early diagnosis of testicular germ cell tumours and for our understanding of regulatory mechanisms , 2002, The Journal of pathology.

[49]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[50]  Ohr,et al.  Tumors of the testis, adnexa, spermatic cord, and scrotum , 2009, Archives of pathology & laboratory medicine.

[51]  A. Rizzino,et al.  Effects of differentiation on the transcriptional regulation of the FGF‐4 gene: Critical roles played by a distal enhancer , 1998, Molecular reproduction and development.

[52]  K. Artzt,et al.  Oct-4 regulates alternative platelet-derived growth factor alpha receptor gene promoter in human embryonal carcinoma cells. , 1996, The Journal of biological chemistry.

[53]  Y. Saijoh,et al.  Identification of putative downstream genes of Oct‐3, a pluripotent cell‐specific transcription factor , 1996, Genes to cells : devoted to molecular & cellular mechanisms.

[54]  Grigor Km.  A new classification of germ cell tumours of the testis. , 1993 .