Interaction Between HIV-1 Nef and Calnexin: From Modeling to Small Molecule Inhibitors Reversing HIV-Induced Lipid Accumulation
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M. Bukrinsky | D. Sviridov | A. Üren | D. Vassylyev | A. Adzhubei | L. Dubrovsky | M. Vassylyeva | A. Anashkina | T. Pushkarsky | Ruth Hunegnaw | B. Brichacek | Tatiana Pushkarsky
[1] M. Clauss,et al. Increased cardiovascular disease risk in the HIV-positive population on ART: potential role of HIV-Nef and Tat. , 2015, Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology.
[2] M. Myerson,et al. Management of lipid disorders in patients living with HIV , 2015, Journal of clinical pharmacology.
[3] M. Bukrinsky,et al. Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection , 2015, The Journal of Pharmacology and Experimental Therapeutics.
[4] R. Ullah,et al. A fruitful decade from 2005 to 2014 for anthraquinone patents , 2015, Expert opinion on therapeutic patents.
[5] B. Sykes,et al. UBC9-dependent Association between Calnexin and Protein Tyrosine Phosphatase 1B (PTP1B) at the Endoplasmic Reticulum* , 2015, The Journal of Biological Chemistry.
[6] The Uniprot Consortium,et al. UniProt: a hub for protein information , 2014, Nucleic Acids Res..
[7] Anastas Popratiloff,et al. HIV-1 Protein Nef Inhibits Activity of ATP-binding Cassette Transporter A1 by Targeting Endoplasmic Reticulum Chaperone Calnexin* , 2014, The Journal of Biological Chemistry.
[8] M. Bukrinsky,et al. HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis , 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[9] Zhiping Weng,et al. ZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers , 2014, Bioinform..
[10] Marco Biasini,et al. SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information , 2014, Nucleic Acids Res..
[11] S. Satija,et al. Conformational transition of membrane-associated terminally acylated HIV-1 Nef. , 2013, Structure.
[12] R. Campbell,et al. Palmitoylation is the switch that assigns calnexin to quality control or ER Ca2+ signaling , 2013, Journal of Cell Science.
[13] Itay Mayrose,et al. ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function , 2013 .
[14] Mieczyslaw Torchala,et al. SwarmDock: a server for flexible protein-protein docking , 2013, Bioinform..
[15] E. Tramontano,et al. New Anthraquinone Derivatives as Inhibitors of the HIV-1 Reverse Transcriptase-Associated Ribonuclease H Function , 2012, Chemotherapy.
[16] Jian Peng,et al. Template-based protein structure modeling using the RaptorX web server , 2012, Nature Protocols.
[17] A. Kihara,et al. Palmitoylated calnexin is a key component of the ribosome–translocon complex , 2012, The EMBO journal.
[18] M. Bukrinsky,et al. HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux[S] , 2012, Journal of Lipid Research.
[19] Jing Ye,et al. Lipid homeostasis and the formation of macrophage-derived foam cells in atherosclerosis , 2012, Protein & Cell.
[20] F. Kashanchi,et al. Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection. , 2012, Biochemical and biophysical research communications.
[21] L. Berthiaume,et al. Palmitoylated TMX and calnexin target to the mitochondria‐associated membrane , 2012, The EMBO journal.
[22] R. Tripathi,et al. A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef , 2011, PloS one.
[23] Ioannis Xenarios,et al. T-Coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension , 2011, Nucleic Acids Res..
[24] A. Gronenborn,et al. Structure, dynamics, and Hck interaction of full‐length HIV‐1 Nef , 2011, Proteins.
[25] Stephen R Comeau,et al. Achieving reliability and high accuracy in automated protein docking: Cluspro, PIPER, SDU, and stability analysis in CAPRI rounds 13–19 , 2010, Proteins.
[26] David W. Ritchie,et al. Ultra-fast FFT protein docking on graphics processors , 2010, Bioinform..
[27] M. Bukrinsky,et al. Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux. , 2010, The Journal of infectious diseases.
[28] F. Kashanchi,et al. Stimulation of the Liver X Receptor Pathway Inhibits HIV-1 Replication via Induction of ATP-Binding Cassette Transporter A1 , 2010, Molecular Pharmacology.
[29] Ian R. Wickersham,et al. Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons , 2010, Nature Protocols.
[30] P. H. Cameron,et al. Calnexin Phosphorylation Attenuates the Release of Partially Misfolded α1-Antitrypsin to the Secretory Pathway* , 2009, The Journal of Biological Chemistry.
[31] E. Freed,et al. Lipids and membrane microdomains in HIV-1 replication. , 2009, Virus research.
[32] A. Olson,et al. AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading , 2009, J. Comput. Chem..
[33] Janusz M. Bujnicki,et al. MetaMQAP: A meta-server for the quality assessment of protein models , 2008, BMC Bioinformatics.
[34] T. Simmen,et al. The subcellular distribution of calnexin is mediated by PACS-2. , 2008, Molecular biology of the cell.
[35] András Fiser,et al. M4T: a comparative protein structure modeling server , 2007, Nucleic Acids Res..
[36] M. Geyer,et al. Specific and distinct determinants mediate membrane binding and lipid raft incorporation of HIV-1(SF2) Nef. , 2006, Virology.
[37] M. Bukrinsky,et al. Human Immunodeficiency Virus Impairs Reverse Cholesterol Transport from Macrophages , 2006, PLoS Biology.
[38] Matthew J. Bentham,et al. Role of myristoylation and N-terminal basic residues in membrane association of the human immunodeficiency virus type 1 Nef protein. , 2006, The Journal of general virology.
[39] S. Breuer,et al. Biochemical indication for myristoylation-dependent conformational changes in HIV-1 Nef. , 2006, Biochemistry.
[40] Marc A. Martí-Renom,et al. MODBASE: a database of annotated comparative protein structure models and associated resources , 2005, Nucleic Acids Res..
[41] M. Freeman,et al. Purification of ATP-binding Cassette Transporter A1 and Associated Binding Proteins Reveals the Importance of β1-Syntrophin in Cholesterol Efflux* , 2005, Journal of Biological Chemistry.
[42] Johannes Söding,et al. The HHpred interactive server for protein homology detection and structure prediction , 2005, Nucleic Acids Res..
[43] A. Helenius,et al. Roles of N-linked glycans in the endoplasmic reticulum. , 2004, Annual review of biochemistry.
[44] Marek Michalak,et al. Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control. , 2004, Molecular cell.
[45] D. Y. Thomas,et al. The Structure of calnexin, an ER chaperone involved in quality control of protein folding. , 2001, Molecular cell.
[46] U. Danilczyk,et al. The Lectin Chaperone Calnexin Utilizes Polypeptide-based Interactions to Associate with Many of Its Substrates in Vivo * , 2001, The Journal of Biological Chemistry.
[47] T. Nagase,et al. Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome. , 2001, Biochemical and biophysical research communications.
[48] H. Roderick,et al. Cytosolic Phosphorylation of Calnexin Controls Intracellular Ca2+ Oscillations via an Interaction with Serca2b , 2000, The Journal of cell biology.
[49] U. Danilczyk,et al. Functional Relationship between Calreticulin, Calnexin, and the Endoplasmic Reticulum Luminal Domain of Calnexin* , 2000, The Journal of Biological Chemistry.
[50] P. H. Cameron,et al. Phosphorylation by CK2 and MAPK enhances calnexin association with ribosomes , 1999, The EMBO journal.
[51] T. Iwakuma,et al. Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system , 1999, Gene Therapy.
[52] Sheena E. Radford,et al. Structural and mechanistic basis of immunity toward endonuclease colicins , 1999, Nature Structural Biology.
[53] T. Ko,et al. The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein. , 1999, Structure.
[54] D. Tessier,et al. Identification and crystallization of a protease-resistant core of calnexin that retains biological activity. , 1998, Journal of structural biology.
[55] Wei R. Chen,et al. The Number and Location of Glycans on Influenza Hemagglutinin Determine Folding and Association with Calnexin and Calreticulin , 1997, The Journal of cell biology.
[56] S. Grzesiek,et al. Refined solution structure and backbone dynamics of HIV‐1 Nef , 1997, Protein science : a publication of the Protein Society.
[57] S. Grzesiek,et al. The solution structure of HIV-1 Nef reveals an unexpected fold and permits delineation of the binding surface for the SH3 domain of Hck tyrosine protein kinase , 1996, Nature Structural Biology.
[58] G. Moore,et al. Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 1. Diffusion-controlled association and femtomolar binding for the cognate complex. , 1995, Biochemistry.
[59] H Videler,et al. Protein-protein interactions in colicin E9 DNase-immunity protein complexes. 2. Cognate and noncognate interactions that span the millimolar to femtomolar affinity range. , 1995, Biochemistry.
[60] D. Clarke,et al. Prolonged association of temperature-sensitive mutants of human P-glycoprotein with calnexin during biogenesis. , 1994, The Journal of biological chemistry.
[61] J. Riordan,et al. Participation of the endoplasmic reticulum chaperone calnexin (p88, IP90) in the biogenesis of the cystic fibrosis transmembrane conductance regulator. , 1994, The Journal of biological chemistry.
[62] M. Lenburg,et al. Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain , 1994, Cell.
[63] R. Swanstrom,et al. Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo , 1993, Journal of virology.
[64] R. Goody,et al. HIV-1 Nef membrane association depends on charge, curvature, composition and sequence. , 2010, Nature chemical biology.
[65] M. Sternberg,et al. Protein structure prediction on the Web: a case study using the Phyre server , 2009, Nature Protocols.
[66] Brian K. Shoichet,et al. ZINC - A Free Database of Commercially Available Compounds for Virtual Screening , 2005, J. Chem. Inf. Model..
[67] V. Ovod,et al. Expression kinetics and subcellular localization of HIV-1 regulatory proteins Nef, Tat and Rev in acutely and chronically infected lymphoid cell lines , 2005, Archives of Virology.
[68] M. Hesselink,et al. Optimisation of oil red O staining permits combination with immunofluorescence and automated quantification of lipids , 2001, Histochemistry and Cell Biology.
[69] H. Berman,et al. Electronic Reprint Biological Crystallography the Protein Data Bank Biological Crystallography the Protein Data Bank , 2022 .