Paracrine Control of Follicular Estrogen Synthesis

Endocrine actions of FSH and LH on the ovarian follicle are transduced by multiple regulatory factors that are produced and have actions within the follicle wall. Such a local (paracrine) type of control is em bodied in the "two-cell, two-gonadotropin" model of follicular estrogen synthesis 1 that not only provided the first satisfactory explanation of the cellular basis of follicular estrogen synthesis but also laid the

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