Autoregulation of Blood Flow

A UTOREGULATION of blood flow, the tenden/ \ cy for blood flow to remain constant despite A. \ . changes in arterial perfusion pressure, is a ubiquitous and much studied phenomenon. Autoregulation was first described in the kidney in 1931, but it had been anticipated by Bayliss 30 years earlier based on changes in hind limb volume during alterations in arterial pressure. Bayliss noted a secondary decrease of organ volume with arterial pressure elevation and suggested that "the peripheral powers of reaction possessed by the arteries is of such a nature as to provide so far as possible for the maintenance of a constant flow of blood through the tissues supplied by them, whatever may be the height of the blood pressure, except so far as they are directly overruled by impulses from the central nervous system." The widespread occurrence of autoregulation in various organs of the body began to be recognized in the 1950's as part of an intensified interest in local mechanisms of blood flow regulation. In 1963 a symposium on this topic, provided a detailed view of the field at that time.

[1]  J. Eckenhoff,et al.  Cardiac oxygen metabolism and control of the coronary circulation. , 1947, The American journal of physiology.

[2]  W. Stainsby.  AUTOREGULATION IN SKELETAL MUSCLE. , 1964, Circulation research.

[3]  G GOERANSSON,et al.  THE METABOLISM OF FATTY ACIDS IN THE RAT. VI. ARACHIDONIC ACID. , 1965, Acta physiologica Scandinavica.

[4]  P. Johnson,et al.  Effect of arterial pressure on arterial and venous resistance of intestine. , 1962, Journal of applied physiology.

[5]  K. Fuxe,et al.  THE DISTRIBUTION OF ADRENERGIC NERVE FIBRES TO THE BLOOD VESSELS IN SKELETAL MUSCLE. , 1965, Acta physiologica Scandinavica.

[6]  E. Bulbring.  Correlation between membrane potential, spike discharge and tension in smooth muscle. , 1955, The Journal of physiology.

[7]  P. Johnson,et al.  Evidence for local arteriovenous reflex in intestine. , 1962, Journal of applied physiology.

[8]  P. Johnson.  Myogenic Nature of Increase in Intestinal Vascular Resistance with Venous Pressure Elevation , 1959, Circulation research.

[9]  J. Walker,et al.  EVIDENCE FOR TISSUE OXYGEN DEMAND AS THE MAJOR FACTOR CAUSING AUTOREGULATION. , 1964, Circulation research.

[10]  P. Johnson.  Autoregulation of intestinal blood flow , 1960 .

[11]  R. Berne,et al.  Evidence for a Metabolic Mechanism in Autoregulation of Blood Flow in Skeletal Muscle , 1965, Circulation research.

[12]  P. Johnson,et al.  Effect of Acute Elevation of Portal Venous Pressure on Mesenteric Blood Volume, Interstitial Fluid Volume and Hemodynamics , 1958, Circulation research.

[13]  R. F. Shaw,et al.  Control of Coronary Blood Flow by an Autoregulatory Mechanism , 1964, Circulation research.

[14]  H. D. Green,et al.  BLOOD FLOW IN PASSIVE VASCULAR BEDS. , 1964, Circulation research.

[15]  H. Rein.  Vasomotorische Regulationen , 2022 .

[16]  K. Thurau.  AUTOREGULATION OF RENAL BLOOD FLOW AND GLOMERULAR FILTRATION RATE, INCLUDING DATA ON TUBULAR AND PERITUBULAR CAPILLARY PRESSURES AND VESSEL WALL TENSION. , 1964, Circulation research.

[17]  A. Koch.  SOME MATHEMATICAL FORMS OF AUTOREGULATORY MODELS. , 1964, Circulation research.

[18]  E. Häggendal,et al.  Effects of arterial carbon dioxide tension and oxygen saturation on cerebral blood flow autoregulation in dogs. , 1965, Acta physiologica Scandinavica. Supplementum.

[19]  I. Kjellmer.  STUDIES ON EXERCISE HYPEREMIA. , 1964, Acta physiologica Scandinavica. Supplementum.

[20]  H. D. Green,et al.  AUTOREGULATION OF CANINE CEREBRAL BLOOD FLOW. , 1964, Circulation Research.

[21]  W. Bayliss.  On the local reactions of the arterial wall to changes of internal pressure , 1902, The Journal of physiology.

[22]  R. Shanks,et al.  Cause of Genuine Autoregulation of the Renal Circulation , 1960, Circulation research.