Impairment of Glycolysis-Derived l-Serine Production in Astrocytes Contributes to Cognitive Deficits in Alzheimer's Disease.
暂无分享,去创建一个
Michel E. Vandenberghe | G. Knott | S. Oliet | B. Cauli | G. Bonvento | C. Duyckaerts | Xavier Toussay | A. Panatier | A. Bemelmans | E. Guiot | E. Brouillet | P. Hantraye | M. Taverna | T. Delzescaux | A. Pruvost | A. Hérard | S. Marinesco | S. Furuya | S. Goutal | Juliette Le Douce | V. Sazdovitch | M. Gaillard | K. Cambon | L. Stimmer | Pierrick Jégo | J. Véran | M. Maugard | M. Matos | Pierre-Antoine Vigneron | E. Faivre | Yaël Balbastre | Juliette Piquet | N. T. Tran | Ayumi Koyanagi | M. Gaudin-Guérif | Aurélie Ghettas | N. Tran | Marco Matos | Mylène Gaudin-Guérif
[1] F. Ciruela,et al. l-Serine dietary supplementation is associated with clinical improvement of loss-of-function GRIN2B-related pediatric encephalopathy , 2019, Science Signaling.
[2] Angus M. Brown,et al. Current technical approaches to brain energy metabolism , 2018, Glia.
[3] Pierre J. Magistretti,et al. Lactate in the brain: from metabolic end-product to signalling molecule , 2018, Nature Reviews Neuroscience.
[4] L. Ferrucci,et al. Evidence for brain glucose dysregulation in Alzheimer's disease , 2018, Alzheimer's & Dementia.
[5] B. Weber,et al. CrossTalk proposal: an important astrocyte‐to‐neuron lactate shuttle couples neuronal activity to glucose utilisation in the brain , 2018, The Journal of physiology.
[6] Andrew J. Saykin,et al. Spatial patterns of neuroimaging biomarker change in individuals from families with autosomal dominant Alzheimer disease: a longitudinal study , 2018, The Lancet Neurology.
[7] L. K. Bak,et al. CrossTalk opposing view: lack of evidence supporting an astrocyte‐to‐neuron lactate shuttle coupling neuronal activity to glucose utilisation in the brain , 2018, The Journal of physiology.
[8] H. Lane,et al. Blood levels of D-amino acid oxidase vs. D-amino acids in reflecting cognitive aging , 2017, Scientific Reports.
[9] Joana S. Ferreira,et al. Co-agonists differentially tune GluN2B-NMDA receptor trafficking at hippocampal synapses , 2017, eLife.
[10] F. LaFerla,et al. Synaptic Impairment in Alzheimer’s Disease: A Dysregulated Symphony , 2017, Trends in Neurosciences.
[11] Marina Boccardi,et al. Clinical validity of brain fluorodeoxyglucose positron emission tomography as a biomarker for Alzheimer's disease in the context of a structured 5-phase development framework , 2017, Neurobiology of Aging.
[12] P. Cox,et al. Traditional Food Items in Ogimi, Okinawa: l-Serine Content and the Potential for Neuroprotection , 2017, Current Nutrition Reports.
[13] Manoj Kumar,et al. INGE GRUNDKE-IQBAL AWARD FOR ALZHEIMER’S RESEARCH: NEUROTOXIC REACTIVE ASTROCYTES ARE INDUCED BY ACTIVATED MICROGLIA , 2019, Alzheimer's & Dementia.
[14] Robert G. Miller,et al. Phase I clinical trial of safety of L-serine for ALS patients , 2017, Amyotrophic lateral sclerosis & frontotemporal degeneration.
[15] M. Ahissar,et al. Neurophysiological mechanisms of cortical plasticity impairments in schizophrenia and modulation by the NMDA receptor agonist D-serine. , 2016, Brain : a journal of neurology.
[16] M. V. Vander Heiden,et al. The importance of serine metabolism in cancer , 2016, The Journal of cell biology.
[17] Norbert Schuff,et al. Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis , 2016, Nature Communications.
[18] M. Verbeek,et al. CSF d-serine concentrations are similar in Alzheimer's disease, other dementias, and elderly controls , 2016, Neurobiology of Aging.
[19] B. Lambolez,et al. Nicotinic Transmission onto Layer 6 Cortical Neurons Relies on Synaptic Activation of Non-α7 Receptors. , 2016, Cerebral cortex.
[20] Ben A. Barres,et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models , 2016, Science.
[21] Marc Dhenain,et al. High-throughput 3D whole-brain quantitative histopathology in rodents , 2016, Scientific Reports.
[22] H. Sugimoto,et al. Bioanalytical method for the simultaneous determination of D- and L-serine in human plasma by LC/MS/MS. , 2015, Analytical biochemistry.
[23] W. Chung,et al. Mutations in SLC1A4, encoding the brain serine transporter, are associated with developmental delay, microcephaly and hypomyelination , 2015, Journal of Medical Genetics.
[24] Pierre J. Magistretti,et al. A Cellular Perspective on Brain Energy Metabolism and Functional Imaging , 2015, Neuron.
[25] J. Laks,et al. d-serine levels in Alzheimer's disease: implications for novel biomarker development , 2015, Translational Psychiatry.
[26] K. Janes. An analysis of critical factors for quantitative immunoblotting , 2015, Science Signaling.
[27] Jesse D. Sengillo,et al. GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration , 2015, Nature Neuroscience.
[28] A. McDonough,et al. Considerations when quantitating protein abundance by immunoblot. , 2015, American journal of physiology. Cell physiology.
[29] B. Weber,et al. Channel-Mediated Lactate Release by K+-Stimulated Astrocytes , 2015, The Journal of Neuroscience.
[30] J. Sahel,et al. Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa , 2015, Molecular therapy : the journal of the American Society of Gene Therapy.
[31] Andrei G. Vlassenko,et al. Brain aerobic glycolysis functions and Alzheimer’s disease , 2015, Clinical and Translational Imaging.
[32] Ann D. Cohen,et al. Early detection of Alzheimer's disease using PiB and FDG PET , 2014, Neurobiology of Disease.
[33] A. Hoischen,et al. Neu-Laxova syndrome is a heterogeneous metabolic disorder caused by defects in enzymes of the L-serine biosynthesis pathway. , 2014, American journal of human genetics.
[34] Yong Jeong,et al. GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease , 2014, Nature Medicine.
[35] Pascal Jourdain,et al. Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons , 2014, Proceedings of the National Academy of Sciences.
[36] Bradley T. Hyman,et al. The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease , 2014, Neuron.
[37] S. Snyder,et al. d-Serine in Glia and Neurons Derives from 3-Phosphoglycerate Dehydrogenase , 2013, The Journal of Neuroscience.
[38] J. Alferink,et al. Effects of Chronic D-Serine Elevation on Animal Models of Depression and Anxiety-Related Behavior , 2013, PloS one.
[39] Antonia García,et al. Optimization and validation of a capillary electrophoresis laser‐induced fluorescence method for amino acids determination in human plasma: Application to bipolar disorder study , 2013, Electrophoresis.
[40] T. Coşkun,et al. An update on serine deficiency disorders , 2013, Journal of Inherited Metabolic Disease.
[41] G. Alexander,et al. Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease. , 2013, JAMA neurology.
[42] Alejandro San Martín,et al. A Genetically Encoded FRET Lactate Sensor and Its Use To Detect the Warburg Effect in Single Cancer Cells , 2013, PloS one.
[43] D. Attwell,et al. Synaptic Energy Use and Supply , 2012, Neuron.
[44] S. Oliet,et al. Synaptic and Extrasynaptic NMDA Receptors Are Gated by Different Endogenous Coagonists , 2012, Cell.
[45] T. Hornemann,et al. Oral L-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1. , 2011, The Journal of clinical investigation.
[46] M. V. Vander Heiden,et al. Aerobic glycolysis: meeting the metabolic requirements of cell proliferation. , 2011, Annual review of cell and developmental biology.
[47] Gregory Stephanopoulos,et al. Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis , 2012, BMC Proceedings.
[48] L. Schneider,et al. Lack of evidence for the efficacy of memantine in mild Alzheimer disease. , 2011, Archives of neurology.
[49] Abhishek K. Jha,et al. Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer , 2011 .
[50] D. Barbier,et al. Covalent enzyme immobilization by poly(ethylene glycol) diglycidyl ether (PEGDE) for microelectrode biosensor preparation. , 2011, Biosensors & bioelectronics.
[51] Sarah A. Stern,et al. Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation , 2011, Cell.
[52] T. Ohshima,et al. Soy Peptide Ingestion Increases Neuroactive Amino Acids in the Adult Brain of Wild-Type and Genetically Engineered Serine-Deficient Mice , 2011 .
[53] Masahiko Watanabe,et al. Brain-specific Phgdh Deletion Reveals a Pivotal Role for l-Serine Biosynthesis in Controlling the Level of d-Serine, an N-methyl-d-aspartate Receptor Co-agonist, in Adult Brain* , 2010, The Journal of Biological Chemistry.
[54] E. Mufson,et al. Staging of Alzheimer's Pathology in Triple Transgenic Mice: A Light and Electron Microscopic Analysis , 2010, International journal of Alzheimer's disease.
[55] Vincent Frouin,et al. Validation of MRI-based 3D digital atlas registration with histological and autoradiographic volumes: An anatomofunctional transgenic mouse brain imaging study , 2010, NeuroImage.
[56] Marc Dhenain,et al. Detection by voxel-wise statistical analysis of significant changes in regional cerebral glucose uptake in an APP/PS1 transgenic mouse model of Alzheimer's disease , 2010, NeuroImage.
[57] A. Halestrap,et al. AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7–10 , 2009, The Biochemical journal.
[58] S. Oliet,et al. Long term potentiation depends on release of D-serine from astrocytes , 2009, Nature.
[59] S. Moncada,et al. The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1 , 2009, Nature Cell Biology.
[60] Vincent Frouin,et al. Quantitative validation of voxel-wise statistical analyses of autoradiographic rat brain volumes: Application to unilateral visual stimulation , 2008, NeuroImage.
[61] E. Head,et al. Lack of Pathology in a Triple Transgenic Mouse Model of Alzheimer's Disease after Overexpression of the Anti-Apoptotic Protein Bcl-2 , 2008, The Journal of Neuroscience.
[62] Loredano Pollegioni,et al. Characterization of a yeast D-amino acid oxidase microbiosensor for D-serine detection in the central nervous system. , 2007, Analytical chemistry.
[63] M. D. de Leon,et al. Hypometabolism exceeds atrophy in presymptomatic early-onset familial Alzheimer's disease. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[64] S. Oliet,et al. Glia-Derived d-Serine Controls NMDA Receptor Activity and Synaptic Memory , 2006, Cell.
[65] C. Jack,et al. Alzheimer's Disease Neuroimaging Initiative , 2008 .
[66] L. Dorland,et al. Prenatal and early postnatal treatment in 3-phosphoglycerate-dehydrogenase deficiency , 2004, The Lancet.
[67] M. Poo,et al. Contribution of astrocytes to hippocampal long-term potentiation through release of d-serine , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[68] M. Mattson,et al. Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles Intracellular Aβ and Synaptic Dysfunction , 2003, Neuron.
[69] K. Willecke,et al. hGFAP‐cre transgenic mice for manipulation of glial and neuronal function in vivo , 2001, Genesis.
[70] Daniel Rueckert,et al. Nonrigid registration using free-form deformations: application to breast MR images , 1999, IEEE Transactions on Medical Imaging.
[71] I. Silver,et al. Extracellular glucose concentration in mammalian brain: continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[72] R. Morris. Developments of a water-maze procedure for studying spatial learning in the rat , 1984, Journal of Neuroscience Methods.
[73] Sholl Da. Dendritic organization in the neurons of the visual and motor cortices of the cat. , 1953 .
[74] D. Sholl. Dendritic organization in the neurons of the visual and motor cortices of the cat. , 1953, Journal of anatomy.