A systematic review of risk factors for cerebral palsy in children born at term in developed countries

Aim  The aim of this study was to conduct a systematic review in order to identify the risk factors for cerebral palsy (CP) in children born at term. The secondary aim was to ascertain if the potential for prevention of these risk factors has been adequately explored.

[1]  P. Curatolo,et al.  Risk factors for the co-occurrence of partial epilepsy, cerebral palsy and mental retardation. , 1995, Developmental Medicine & Child Neurology.

[2]  C. Torfs,et al.  Prenatal and perinatal factors in the etiology of cerebral palsy. , 1990, The Journal of pediatrics.

[3]  B. Jacobsson,et al.  Risk factors for cerebral palsy in children born at term , 2011, Acta obstetricia et gynecologica Scandinavica.

[4]  S. Tough,et al.  Delayed child-bearing. , 2012, Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC.

[5]  K. Himmelmann,et al.  The changing panorama of cerebral palsy in Sweden. X. Prevalence and origin in the birth‐year period 1999–2002 , 2010, Acta paediatrica.

[6]  R. Kane,et al.  A systematic review of tools used to assess the quality of observational studies that examine incidence or prevalence and risk factors for diseases. , 2010, Journal of clinical epidemiology.

[7]  Juan Pablo Peña-Rosas,et al.  Effects and safety of periconceptional folate supplementation for preventing birth defects. , 2010, The Cochrane database of systematic reviews.

[8]  D. Booth,et al.  Anticonvulsants for neonates with seizures. , 2004, The Cochrane database of systematic reviews.

[9]  F. Stanley,et al.  Report of the Western Australian Cerebral Palsy Register - to birth year 1999 , 1999 .

[10]  C. Greenwood,et al.  Why is there a modifying effect of gestational age on risk factors for cerebral palsy? , 2005, Archives of Disease in Childhood - Fetal and Neonatal Edition.

[11]  M. Stazi,et al.  RISK FACTORS FOR THE COOCCURRENCE OF PARTIAL EPILEPSY, CEREBRAL PALSY AND MENTAL RETARDATION , 1995 .

[12]  Taeun Chang,et al.  Is cerebral palsy preventable? , 2008, Current opinion in neurology.

[13]  Juan Pablo Peña-Rosas,et al.  Effects and safety of periconceptional oral folate supplementation for preventing birth defects. , 2015, The Cochrane database of systematic reviews.

[14]  Ann Johnson,et al.  Cerebral palsies: epidemiology and causal pathways , 2000, Archives of disease in childhood.

[15]  Nadia Badawi,et al.  The origins of cerebral palsy , 2006, Current opinion in neurology.

[16]  F. Stanley,et al.  Aetiological pathways to spastic cerebral palsy. , 1993, Paediatric and perinatal epidemiology.

[17]  Andrew M. Kaunitz,et al.  Labor Induction Versus Expectant Management for Postterm Pregnancies: A Systematic Review With Meta‐analysis , 2003, Obstetrics and gynecology.

[18]  T. Talvik,et al.  Ante- and Perinatal Factors for Cerebral Palsy: Case-Control Study in Estonia , 2005, Journal of child neurology.

[19]  E. Blair,et al.  Antenatal antecedents of moderate and severe cerebral palsy. , 1995, Paediatric and perinatal epidemiology.

[20]  J. Sinn,et al.  Steroid therapy for meconium aspiration syndrome in newborn infants. , 2003, The Cochrane database of systematic reviews.

[21]  K. Nelson,et al.  Placental infarction identified by macroscopic examination and risk of cerebral palsy in infants at 35 weeks of gestational age and over. , 2011, American journal of obstetrics and gynecology.

[22]  Obstetric complications as risk factors for cerebral palsy or seizure disorders. , 1984, JAMA.

[23]  G. Hofmeyr.  What (not) to do before delivery? Prevention of fetal meconium release and its consequences. , 2009, Early human development.

[24]  G. Hofmeyr,et al.  Cephalic version by postural management for breech presentation. , 2000, The Cochrane database of systematic reviews.

[25]  B. Dan,et al.  A report: the definition and classification of cerebral palsy April 2006 , 2007, Developmental medicine and child neurology. Supplement.

[26]  M. Lindheimer,et al.  Maternal infection and risk of preeclampsia: systematic review and metaanalysis. , 2008, American journal of obstetrics and gynecology.

[27]  A. Herbst,et al.  Perinatal Factors Associated With Cerebral Palsy in Children Born in Sweden , 2006, Obstetrics and gynecology.

[28]  S. Brennecke,et al.  Factors identified during the neonatal period associated with risk of cerebral palsy , 2004, The Australian & New Zealand journal of obstetrics & gynaecology.

[29]  K. Nelson,et al.  Cerebral palsy in four northern California counties, births 1983 through 1985. , 1993, The Journal of pediatrics.

[30]  W. McGuire,et al.  Prophylactic versus selective antibiotics for term newborn infants of mothers with risk factors for neonatal infection. , 2004, The Cochrane database of systematic reviews.

[31]  H. Jeffery,et al.  Antibiotic regimens for suspected late onset sepsis in newborn infants. , 2005, The Cochrane database of systematic reviews.

[32]  Yvonne W Wu,et al.  Cerebral Palsy in a Term Population: Risk Factors and Neuroimaging Findings , 2006, Pediatrics.

[33]  I. Krägeloh-Mann,et al.  Trends in prevalence of cerebral palsy in children born with a birthweight of 2,500 g or over in Europe from 1980 to 1998 , 2010, European Journal of Epidemiology.

[34]  J H Ellenberg,et al.  Antecedents of cerebral palsy. I. Univariate analysis of risks. , 1986, American journal of diseases of children.

[35]  U. Yılmaz,et al.  The role of perinatal and intrapartum risk factors in the etiologyof cerebral palsy in term deliveries in a Turkish population , 2006, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[36]  J. Kingdom,et al.  Antithrombotic therapy for improving maternal or infant health outcomes in women considered at risk of placental dysfunction. , 2013, The Cochrane database of systematic reviews.

[37]  F. Stanley,et al.  An Epidemiological Study of Cerebral Palsy in Western Australia, 1956–1975. II: Spastic Cerebral Palsy and Perinatal Factors , 1980, Developmental medicine and child neurology.

[38]  E. Sheiner,et al.  A significant linear association exists between advanced maternal age and adverse perinatal outcome , 2011, Archives of Gynecology and Obstetrics.

[39]  A. Ohlsson,et al.  Intravenous immunoglobulin for suspected or subsequently proven infection in neonates. , 2004, The Cochrane database of systematic reviews.

[40]  K. Nelson,et al.  Can we prevent cerebral palsy? , 2003, The New England journal of medicine.

[41]  J. Rehm,et al.  Dose–response relationship between alcohol consumption before and during pregnancy and the risks of low birthweight, preterm birth and small for gestational age (SGA)—a systematic review and meta‐analyses , 2011, BJOG : an international journal of obstetrics and gynaecology.

[42]  J. Spencer-Jones,et al.  Make every mother and child count. , 2005, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[43]  E. Dempsey,et al.  Early blood glucose profile and neurodevelopmental outcome at two years in neonatal hypoxic-ischaemic encephalopathy , 2011, BMC pediatrics.

[44]  G. Gyte,et al.  Interventions to help external cephalic version for breech presentation at term. , 2004, The Cochrane database of systematic reviews.

[45]  J. Higgins,et al.  Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography. , 2007, International journal of epidemiology.

[46]  J. Pell,et al.  Advanced maternal age and the risk of perinatal death due to intrapartum anoxia at term , 2010, Journal of Epidemiology & Community Health.

[47]  G. Hofmeyr.  Amnioinfusion for meconium-stained liquor in labour. , 2002, The Cochrane database of systematic reviews.

[48]  C. Crowther,et al.  Magnesium supplementation in pregnancy. , 2014, The Cochrane database of systematic reviews.

[49]  I. Olkin,et al.  Meta-analysis of observational studies in epidemiology - A proposal for reporting , 2000 .

[50]  Hofmeyr Gj.  Interventions to help external cephalic version for breech presentation at term , 2004 .

[51]  J. Ellenberg,et al.  Antecedents of cerebral palsy. Multivariate analysis of risk. , 1986, The New England journal of medicine.

[52]  S. Brennecke,et al.  Antenatal and intrapartum antecedents of cerebral palsy: a case‐control study , 2002, The Australian & New Zealand journal of obstetrics & gynaecology.

[53]  P. Davis,et al.  Cooling for newborns with hypoxic ischaemic encephalopathy. , 2013, The Cochrane database of systematic reviews.

[54]  Asphyxia‐related risk factors and their timing in spastic cerebral palsy , 2008, BJOG : an international journal of obstetrics and gynaecology.

[55]  R. Soll,et al.  Multiple versus single doses of exogenous surfactant for the prevention or treatment of neonatal respiratory distress syndrome. , 2009, The Cochrane database of systematic reviews.

[56]  M. Falagas,et al.  Short versus long duration of antibiotic therapy for bacterial meningitis: a meta-analysis of randomised controlled trials in children , 2009, Archives of Disease in Childhood.

[57]  G. Hofmeyr,et al.  External cephalic version for breech presentation at term. , 2000, The Cochrane database of systematic reviews.

[58]  T. Einarson,et al.  Prenatal Multivitamin Supplementation and Rates of Congenital Anomalies: a Meta-analysis , 2022 .

[59]  R. T. Lie,et al.  Cerebral Palsy Among Term and Post-term Births , 2011 .

[60]  B. Peat,et al.  Cephalic version by moxibustion for breech presentation. , 2005, The Cochrane database of systematic reviews.

[61]  A. Johnson,et al.  Case-control study of intrapartum care, cerebral palsy, and perinatal death , 1994, BMJ.

[62]  P. Dargaville,et al.  Surfactant for meconium aspiration syndrome in full term/near term infants. , 2007, The Cochrane database of systematic reviews.

[63]  C. Van den Broeck,et al.  Prevalence, type, distribution, and severity of cerebral palsy in relation to gestational age: a meta‐analytic review , 2008, Developmental medicine and child neurology.

[64]  W. Kułak,et al.  Risk factors for cerebral palsy in term birth infants. , 2010, Advances in medical sciences.

[65]  F. Stanley,et al.  When can cerebral palsy be prevented? The generation of causal hypotheses by multivariate analysis of a case-control study. , 1993, Paediatric and perinatal epidemiology.

[66]  J. R. Wilkins,et al.  Cerebral palsy: evaluation of a model of risk. , 1993, Research in nursing & health.