Synthesis and pharmacological activity of the epimers of hexahydrocannabinol (HHC)

[1]  I. Ujváry Hexahydrocannabinol and closely related semi-synthetic cannabinoids: A comprehensive review. , 2023, Drug testing and analysis.

[2]  G. Roda,et al.  Hexahydrocannabinol on the Light Cannabis Market: The Latest "New" Entry. , 2022, Cannabis and cannabinoid research.

[3]  G. Biagini,et al.  Cis-Δ9-tetrahydrocannabinolic acid occurrence in Cannabis sativa L. , 2022, Journal of pharmaceutical and biomedical analysis.

[4]  E. Leas The Hemp Loophole: A Need to Clarify the Legality of Delta-8-THC and Other Hemp-Derived Tetrahydrocannabinol Compounds. , 2021, American journal of public health.

[5]  G. Gigli,et al.  HPLC-UV-HRMS analysis of cannabigerovarin and cannabigerobutol, the two impurities of cannabigerol extracted from hemp. , 2021, Journal of pharmaceutical and biomedical analysis.

[6]  G. Gigli,et al.  Identification of a new cannabidiol n-hexyl homolog in a medicinal cannabis variety with an antinociceptive activity in mice: cannabidihexol , 2020, Scientific Reports.

[7]  Esther J Pearl,et al.  The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research , 2020, PLoS biology.

[8]  G. Gigli,et al.  Origin of Δ9-Tetrahydrocannabinol Impurity in Synthetic Cannabidiol. , 2020, Cannabis and cannabinoid research.

[9]  G. Gigli,et al.  Isolation of a High-Affinity Cannabinoid for the Human CB1 Receptor from a Medicinal Cannabis sativa Variety: Δ9-Tetrahydrocannabutol, the Butyl Homologue of Δ9-Tetrahydrocannabinol. , 2019, Journal of natural products.

[10]  G. Gigli,et al.  A novel phytocannabinoid isolated from Cannabis sativa L. with an in vivo cannabimimetic activity higher than Δ9-tetrahydrocannabinol: Δ9-Tetrahydrocannabiphorol , 2019, Scientific Reports.

[11]  anonymous,et al.  Comprehensive review , 2019 .

[12]  S. Benvenuti,et al.  Development of a new extraction technique and HPLC method for the analysis of non‐psychoactive cannabinoids in fibre‐type Cannabis sativa L. (hemp) , 2017, Journal of pharmaceutical and biomedical analysis.

[13]  P. Piazza,et al.  Cannabinoid‐Induced Tetrad in Mice , 2017, Current protocols in neuroscience.

[14]  Giuseppe Cannazza,et al.  Medicinal cannabis: Principal cannabinoids concentration and their stability evaluated by a high performance liquid chromatography coupled to diode array and quadrupole time of flight mass spectrometry method. , 2016, Journal of pharmaceutical and biomedical analysis.

[15]  J. Rimoldi,et al.  The Structure–Function Relationships of Classical Cannabinoids: CB1/CB2 Modulation , 2016, Perspectives in medicinal chemistry.

[16]  L. Orsolini,et al.  NPS: Medical Consequences Associated with Their Intake. , 2016, Current topics in behavioral neurosciences.

[17]  Matt Anderson,et al.  European Monitoring Centre for Drugs and Drug Addiction , 2014 .

[18]  M. Musselman,et al.  “Not for Human Consumption”: A Review of Emerging Designer Drugs , 2014, Pharmacotherapy.

[19]  S. Bera,et al.  A new insight into Cannabis sativa (Cannabaceae) utilization from 2500-year-old Yanghai Tombs, Xinjiang, China. , 2006, Journal of ethnopharmacology.

[20]  P. Reggio,et al.  The importance of the orientation of the C9 substituent to cannabinoid activity. , 1989, Journal of medicinal chemistry.

[21]  T. H. Varkony,et al.  Stereochemical requirements for cannabinoid activity. , 1980, Journal of Medicinal Chemistry.

[22]  R. A. Archer,et al.  Structural studies of cannabinoids. A theoretical and proton magnetic resonance analysis. , 1970, Journal of the American Chemical Society.

[23]  C. K. Cain,et al.  STRUCTURE OF CANNABIDIOL. VIII. POSITION OF THE DOUBLE BONDS IN CANNABIDIOL. MARIHUANA ACTIVITY OF TETRAHYDROCANNABINOLS , 1940 .

[24]  C. K. Cain,et al.  Structure of Cannabidiol. VI. Isomerization of Cannabidiol to Tetrahydrocannabinol, a Physiologically Active Product. Conversion of Cannabidiol to Cannabinol1 , 1940 .

[25]  R. Mechoulam,et al.  Hashish—VII : The isomerization of cannabidiol to tetrahydrocannabinols , 1966 .

[26]  R. Adams,et al.  Structure of Cannabidiol, a Product Isolated from the Marihuana Extract of Minnesota Wild Hemp. I , 1940 .