Visualization research on ENT1/NIS dual-function gene therapy to reverse drug resistance mediated by MUC1 in GEM-resistant pancreatic cancer.
暂无分享,去创建一个
[1] J. Czernin,et al. STING-driven interferon signaling triggers metabolic alterations in pancreas cancer cells visualized by [18F]FLT PET imaging , 2021, Proceedings of the National Academy of Sciences.
[2] R. Greil,et al. Gemcitabine/nab-Paclitaxel versus FOLFIRINOX for palliative first-line treatment of advanced pancreatic cancer: A propensity score analysis. , 2021, European journal of cancer.
[3] F. André,et al. Overcoming Resistance to Tumor-Targeted and Immune-Targeted Therapies. , 2021, Cancer discovery.
[4] R. Gargallo,et al. Structural Effects of Incorporation of 2´-Deoxy-2´2´-difluorodeoxycytidine (Gemcitabine) in A- and B-form Duplexes. , 2021, Chemistry.
[5] Z. Qian,et al. Regulation of tumor microenvironment for pancreatic cancer therapy. , 2021, Biomaterials.
[6] B. Rolando,et al. Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine , 2020, International journal of molecular sciences.
[7] Y. Nishiyama,et al. Liver Abscess With High 18F-FDG Uptake and No 18F-Fluorothymidine Uptake. , 2020, Clinical nuclear medicine.
[8] M. Diener,et al. Top ten research priorities for pancreatic cancer therapy. , 2020, The Lancet. Oncology.
[9] A. Maitra,et al. Pancreatic cancer stroma: an update on therapeutic targeting strategies , 2020, Nature Reviews Gastroenterology & Hepatology.
[10] Mo-Fang Liu,et al. hENT1 Reverses Chemoresistance by Regulating Glycolysis in Pancreatic Cancer. , 2020, Cancer letters.
[11] Mark B. Vestergaard,et al. In vivo imaging of cell proliferation in meningioma using 3′-deoxy-3′-[18F]fluorothymidine PET/MRI , 2020, European Journal of Nuclear Medicine and Molecular Imaging.
[12] D. V. Von Hoff,et al. Effect of Gemcitabine and nab-Paclitaxel With or Without Hydroxychloroquine on Patients With Advanced Pancreatic Cancer: A Phase 2 Randomized Clinical Trial. , 2019, JAMA oncology.
[13] B. V. Van Tine,et al. Arginine Starvation and Docetaxel Induce c-Myc–Driven hENT1 Surface Expression to Overcome Gemcitabine Resistance in ASS1-Negative Tumors , 2019, Clinical Cancer Research.
[14] Ho-Joon Lee,et al. Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer , 2018, bioRxiv.
[15] Miao Zhang,et al. Human sodium iodide transporter gene-mediated imaging and therapy of mouse glioma, comparison between 188Re and 131I. , 2018, Oncology letters.
[16] Quan P. Ly,et al. MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer. , 2017, Cancer cell.
[17] Z. Fan,et al. Gemcitabine inhibits proliferation and induces apoptosis in human pancreatic cancer PANC-1 cells. , 2016, Journal of cancer research and therapeutics.
[18] J. Roa,et al. Low expression of equilibrative nucleoside transporter 1 is associated with poor prognosis in chemotherapy‐naïve pT2 gallbladder adenocarcinoma patients , 2016, Histopathology.
[19] P. Manoharan,et al. 18F-FLT PET imaging of cellular proliferation in pancreatic cancer. , 2016, Critical reviews in oncology/hematology.
[20] Jiajia Hu,et al. 131I therapy mediated by sodium/iodide symporter combined with kringle 5 has a synergistic therapeutic effect on glioma. , 2016, Oncology reports.
[21] Z. Werb,et al. The cancer stem cell niche: how essential is the niche in regulating stemness of tumor cells? , 2015, Cell stem cell.
[22] G. Peters,et al. Inhibition of thymidylate synthase by 2',2'-difluoro-2'-deoxycytidine (Gemcitabine) and its metabolite 2',2'-difluoro-2'-deoxyuridine. , 2015, The international journal of biochemistry & cell biology.
[23] Jian Huang,et al. The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment , 2014, Tumor Biology.
[24] Carol E. Cass,et al. Erlotinib, Gefitinib, and Vandetanib Inhibit Human Nucleoside Transporters and Protect Cancer Cells from Gemcitabine Cytotoxicity , 2013, Clinical Cancer Research.
[25] M. Tempero,et al. Therapeutic advances in pancreatic cancer. , 2013, Gastroenterology.
[26] M. Sehested,et al. [18F]FLT PET for Non-Invasive Assessment of Tumor Sensitivity to Chemotherapy: Studies with Experimental Chemotherapy TP202377 in Human Cancer Xenografts in Mice , 2012, PloS one.
[27] B. Han,et al. Feasibility of a novel positive feedback effect of 131I-promoted Bac-Egr1-hNIS expression in malignant glioma via baculovirus. , 2011, Nuclear medicine and biology.
[28] Ru-fu Chen,et al. In vivo Radioiodide Imaging and Treatment of Pancreatic Cancer Xenografts after MUC1 Promoter-Driven Expression of the Human Sodium-Iodide Symporter , 2007, Pancreatology.
[29] B. Keil,et al. Efficacy of 99mTc pertechnetate and 131I radioisotope therapy in sodium/iodide symporter (NIS)-expressing neuroendocrine tumors in vivo , 2007, European Journal of Nuclear Medicine and Molecular Imaging.
[30] U. Haberkorn,et al. 99mTc-pertechnetate uptake in hepatoma cells due to tissue-specific human sodium iodide symporter gene expression. , 2006, Nuclear medicine and biology.
[31] J. Shah,et al. MUC1 plays a role in tumor maintenance in aggressive thyroid carcinomas. , 2005, Surgery.
[32] M. Kumar,et al. Amplification and functional characterization of MUC1 promoter and gene-virotherapy via a targeting adenoviral vector expressing hSSTR2 gene in MUC1-positive Panc-1 pancreatic cancer cells in vitro. , 2005, International journal of molecular medicine.
[33] John R. Mackey,et al. The Absence of Human Equilibrative Nucleoside Transporter 1 Is Associated with Reduced Survival in Patients With Gemcitabine-Treated Pancreas Adenocarcinoma , 2004, Clinical Cancer Research.
[34] G. Peters,et al. Determinants of resistance to 2′,2′-difluorodeoxycytidine (gemcitabine) , 2002 .
[35] D. V. Von Hoff,et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[36] Y. Namiki,et al. Induction of the suicide HSV-TK gene by activation of the Egr-1 promoter with radioisotopes. , 1997, Human gene therapy.
[37] V. Heinemann,et al. Gemcitabine: metabolism, mechanisms of action, and self-potentiation. , 1995, Seminars in oncology.
[38] O. Warburg. [Origin of cancer cells]. , 1956, Oncologia.
[39] A. Jemal,et al. Cancer statistics, 2019 , 2019, CA: a cancer journal for clinicians.
[40] John R. Mackey,et al. Pancreatic cancer hENT1 expression and survival from gemcitabine in patients from the ESPAC-3 trial. , 2014, Journal of the National Cancer Institute.
[41] Michael R Lewis,et al. A "new" reporter in the field of imaging reporter genes: correlating gene expression and function of the sodium/iodide symporter. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[42] Barry J. Allen,et al. MUC1, MUC2, MUC4, MUC5AC and MUC6 Expression in the Progression of Prostate Cancer , 2005, Clinical & Experimental Metastasis.