Mechanism of activation and inhibition of the HER4/ErbB4 kinase.
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Ron Bose | Ashutosh Pal | Sudeep Banjade | R. Bose | D. Leahy | P. Cole | W. Bornmann | M. Lemmon | Sudeep Banjade | C. Qiu | M. K. Tarrant | Daniel J Leahy | Philip A Cole | Mark A Lemmon | Sung-Hee Choi | A. Pal | Aruna Sathyamurthy | Sung Hee Choi | William G Bornmann | Chen Qiu | Mary K Tarrant | A. Sathyamurthy | Aruna Sathyamurthy
[1] Monilola A. Olayioye,et al. The ErbB signaling network: receptor heterodimerization in development and cancer , 2000, The EMBO journal.
[2] Rüdiger Klein,et al. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor , 1995, Nature.
[3] G N Murshudov,et al. Use of TLS parameters to model anisotropic displacements in macromolecular refinement. , 2001, Acta crystallographica. Section D, Biological crystallography.
[4] N. Hynes,et al. ErbB receptors: directing key signaling networks throughout life. , 2004, Annual review of pharmacology and toxicology.
[5] John Kuriyan,et al. A Src-Like Inactive Conformation in the Abl Tyrosine Kinase Domain , 2006, PLoS biology.
[6] A. Ullrich,et al. Intermolecular transphosphorylation between insulin receptors and EGF‐insulin receptor chimerae. , 1989, The EMBO journal.
[7] M. Lemmon,et al. Extracellular domains drive homo‐ but not hetero‐dimerization of erbB receptors , 2000, The EMBO journal.
[8] Jerry M Maniate,et al. Targeting the EGFR pathway for cancer therapy. , 2006, Current medicinal chemistry.
[9] John Kuriyan,et al. An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor , 2006, Cell.
[10] Z. Otwinowski,et al. [20] Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.
[11] M. Lawrence,et al. Shape complementarity at protein/protein interfaces. , 1993, Journal of molecular biology.
[12] K. Lackey,et al. Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series. , 2006, Bioorganic & medicinal chemistry letters.
[13] M. Karamouzis,et al. Breast cancer: the upgraded role of HER-3 and HER-4. , 2007, The international journal of biochemistry & cell biology.
[14] M. Lemmon,et al. ErbB3/HER3 does not homodimerize upon neuregulin binding at the cell surface , 2004, FEBS letters.
[15] H. Kim,et al. Biochemical characterization of the protein tyrosine kinase homology domain of the ErbB3 (HER3) receptor protein. , 1997, The Biochemical journal.
[16] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[17] Y. Yarden,et al. The ErbB-2/HER2 oncoprotein of human carcinomas may function solely as a shared coreceptor for multiple stroma-derived growth factors. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[18] Samuel Bouyain,et al. The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[19] G. Murshudov,et al. Refinement of macromolecular structures by the maximum-likelihood method. , 1997, Acta crystallographica. Section D, Biological crystallography.
[20] Kornelia Polyak,et al. Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex , 1995, Nature.
[21] Hyun-soo Cho,et al. EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. , 2003, Molecular cell.
[22] Hyun-soo Cho,et al. Structure of the Extracellular Region of HER3 Reveals an Interdomain Tether , 2002, Science.
[23] Christopher P Mill,et al. Inter-conversion of neuregulin2 full and partial agonists for ErbB4. , 2007, Biochemical and biophysical research communications.
[24] M. Sliwkowski,et al. Structure of the Epidermal Growth Factor Receptor Kinase Domain Alone and in Complex with a 4-Anilinoquinazoline Inhibitor* , 2002, The Journal of Biological Chemistry.
[25] H. Lane,et al. ERBB receptors and cancer: the complexity of targeted inhibitors , 2005, Nature Reviews Cancer.
[26] Randy J Read,et al. Electronic Reprint Biological Crystallography Likelihood-enhanced Fast Rotation Functions Biological Crystallography Likelihood-enhanced Fast Rotation Functions , 2003 .
[27] J. Kuriyan,et al. The Conformational Plasticity of Protein Kinases , 2002, Cell.
[28] Michael Kofler,et al. The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. , 2003, Molecular cell.
[29] Y. Yarden,et al. Untangling the ErbB signalling network , 2001, Nature Reviews Molecular Cell Biology.
[30] G. Carpenter,et al. ErbB-4: mechanism of action and biology. , 2003, Experimental cell research.
[31] Kevin Cowtan,et al. research papers Acta Crystallographica Section D Biological , 2005 .
[32] Ron Bose,et al. Inhibition of the EGF Receptor by Binding to an Activating Kinase Domain Interface , 2007, Nature.
[33] A. Ullrich,et al. Transphosphorylation as a possible mechanism for insulin and epidermal growth factor receptor activation. , 1990, The Journal of biological chemistry.
[34] W. Denny. The 4-anilinoquinazoline class of inhibitors of the erbB family of receptor tyrosine kinases. , 2001, Farmaco.
[35] Edouard C. Nice,et al. Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor α , 2002, Cell.
[36] M. Sliwkowski,et al. An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. , 2003, Molecular cell.
[37] G. Plowman,et al. Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[38] D. Stern,et al. Neural and mammary gland defects in ErbB4 knockout mice genetically rescued from embryonic lethality , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[39] Krystal J Alligood,et al. A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib) , 2004, Cancer Research.
[40] Y. Yarden,et al. ErbB‐2 is a common auxiliary subunit of NDF and EGF receptors: implications for breast cancer. , 1996, The EMBO journal.
[41] A. M. Stanley,et al. Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab , 2003, Nature.
[42] K. Lackey,et al. Comparison of the Biochemical and Kinetic Properties of the Type 1 Receptor Tyrosine Kinase Intracellular Domains , 2002, The Journal of Biological Chemistry.
[43] Jae-Hoon Kim,et al. Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains , 2002, Cell.