c-Jun N-terminal kinase upregulation as a key event in the proapoptotic interaction between transforming growth factor-beta1 and 4-hydroxynonenal in colon mucosa.
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N. Žarković | G. Poli | E. Chiarpotto | F. Biasi | G. Leonarduzzi | E. Gaia | C. Mascia | B. Vizio
[1] H. Forman,et al. HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells. , 2005, Free radical biology & medicine.
[2] D. Danielpour,et al. Overexpression of Bax sensitizes prostate cancer cells to TGF-β induced apoptosis , 2005, Cell Research.
[3] T. Ko,et al. TGF-β Signaling in Colon Cancer Cells , 2005, World Journal of Surgery.
[4] A. Sánchez-Capelo. Dual role for TGF-β1 in apoptosis , 2005 .
[5] Federica Briatore,et al. 4-Hydroxynonenal modulation of p53 family gene expression in the SK-N-BE neuroblastoma cell line. , 2005, Free radical biology & medicine.
[6] G. Wolf. New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology , 2004, European journal of clinical investigation.
[7] D. Butterfield,et al. Oxidatively Modified GST and MRP1 in Alzheimer’s Disease Brain: Implications for Accumulation of Reactive Lipid Peroxidation Products , 2004, Neurochemical Research.
[8] K. Uchida,et al. A Lipid Peroxidation-derived Inflammatory Mediator , 2004, Journal of Biological Chemistry.
[9] S. Dupont,et al. Convergence of p53 and TGF-beta signaling networks. , 2004, Cancer letters.
[10] M. Dianzani,et al. 4-hydroxynonenal and regulation of cell cycle: effects on the pRb/E2F pathway. , 2004, Free radical biology & medicine.
[11] G. Aldini,et al. Mass spectrometry for detection of 4-hydroxy-trans-2-nonenal (HNE) adducts with peptides and proteins. , 2004, Mass spectrometry reviews.
[12] G. Poli,et al. Oxidative stress and cell signalling. , 2004, Current medicinal chemistry.
[13] L. Marnett,et al. Induction of apoptosis in colorectal carcinoma cells treated with 4-hydroxy-2-nonenal and structurally related aldehydic products of lipid peroxidation. , 2004, Chemical research in toxicology.
[14] A. Sevanian,et al. Oxysterol mixtures prevent proapoptotic effects of 7‐ ketocholesterol in macrophages: implications for proatherogenic gene modulation , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[15] Suna Wang,et al. Loss of Heterozygosity and Mutational Analyses of the ACTRII Gene Locus in Human Colorectal Tumors , 2003, Laboratory Investigation.
[16] Ying E. Zhang,et al. Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.
[17] C. Sempoux,et al. Oxidative stress, KLF6 and transforming growth factor-beta up-regulation differentiate non-alcoholic steatohepatitis progressing to fibrosis from uncomplicated steatosis in rats. , 2003, Journal of hepatology.
[18] Y. Awasthi,et al. Role of 4-hydroxynonenal in stress-mediated apoptosis signaling. , 2003, Molecular aspects of medicine.
[19] K. Žarković. 4-hydroxynonenal and neurodegenerative diseases. , 2003, Molecular aspects of medicine.
[20] G. Poli,et al. 4-hydroxynonenal and transforming growth factor-beta1 expression in colon cancer. , 2003, Molecular aspects of medicine.
[21] Toshio Kuroki,et al. Role of Smad4 (DPC4) inactivation in human cancer. , 2003, Biochemical and biophysical research communications.
[22] K. Uchida,et al. 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. , 2003, Progress in lipid research.
[23] J. Massagué,et al. Mechanisms of TGF-β Signaling from Cell Membrane to the Nucleus , 2003, Cell.
[24] C. Craciunescu,et al. Activation of a caspase-dependent oxidative damage response mediates TGFbeta1 apoptosis in rat hepatocytes. , 2003, Experimental and molecular pathology.
[25] Sanford Markowitz,et al. TGF-β-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines , 2003, Oncogene.
[26] T. Gant,et al. Characterization of the Transforming Growth Factor-β1-induced Apoptotic Transcriptome in FaO Hepatoma Cells* 210 , 2003, The Journal of Biological Chemistry.
[27] K. Miyazono,et al. Two major Smad pathways in TGF‐β superfamily signalling , 2002, Genes to cells : devoted to molecular & cellular mechanisms.
[28] M. Nitti,et al. Activation of PKC-β isoforms mediates HNE-induced MCP-1 release by macrophages , 2002 .
[29] M. Goumans,et al. Regulation of cell proliferation by Smad proteins , 2002, Journal of cellular physiology.
[30] N. Žarković,et al. Associated changes of lipid peroxidation and transforming growth factor β1 levels in human colon cancer during tumour progression , 2002, Gut.
[31] C. Hill,et al. Loss of Smad4 Function in Pancreatic Tumors , 2001, The Journal of Biological Chemistry.
[32] Allan Balmain,et al. TGF-β signaling in tumor suppression and cancer progression , 2001, Nature Genetics.
[33] L. Marnett,et al. 4-hydroxynonenal induces apoptosis via caspase-3 activation and cytochrome c release. , 2001, Chemical research in toxicology.
[34] Y. Hattori,et al. Vascular smooth muscle cell activation and growth by 4-hydroxynonenal. , 2001, Life sciences.
[35] A. Roberts,et al. Smad3/AP-1 interactions control transcriptional responses to TGF-β in a promoter-specific manner , 2001, Oncogene.
[36] J. Massagué,et al. TGFβ influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b , 2001, Nature Cell Biology.
[37] J. Massagué,et al. TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders , 2000, Cell.
[38] G. Poli,et al. 4‐Hydroxynonenal in the Pathomechanisms of Oxidative Stress , 2000, IUBMB life.
[39] Ester Piek,et al. Role of Transforming Growth Factor-β Signaling in Cancer , 2000 .
[40] Y. Soh,et al. Selective activation of the c-Jun N-terminal protein kinase pathway during 4-hydroxynonenal-induced apoptosis of PC12 cells. , 2000, Molecular pharmacology.
[41] E. Podrez,et al. HNE-derived 2-pentylpyrroles are generated during oxidation of LDL, are more prevalent in blood plasma from patients with renal disease or atherosclerosis, and are present in atherosclerotic plaques. , 2000, Chemical research in toxicology.
[42] G. Poli. Pathogenesis of liver fibrosis: role of oxidative stress. , 2000, Molecular aspects of medicine.
[43] M. Mattson,et al. The Lipid Peroxidation Product 4‐Hydroxy‐2,3‐Nonenal Increases AP‐1‐Binding Activity Through Caspase Activation in Neurons , 2000, Journal of neurochemistry.
[44] Yoshimasa Nakamura,et al. Activation of Stress Signaling Pathways by the End Product of Lipid Peroxidation , 1999, The Journal of Biological Chemistry.
[45] G. Bellomo,et al. HNE interacts directly with JNK isoforms in human hepatic stellate cells. , 1998, The Journal of clinical investigation.
[46] G. Poli,et al. The lipid peroxidation end product 4‐hydroxy‐2,3‐nonenal up‐regulates transforming growth factor β1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis 1 , 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[47] Luzhe Sun,et al. Demonstration That Mutation of the Type II Transforming Growth Factor β Receptor Inactivates Its Tumor Suppressor Activity in Replication Error-positive Colon Carcinoma Cells (*) , 1995, The Journal of Biological Chemistry.
[48] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.
[49] G. Poli,et al. 4‐Hydroxynonenal and TGF‐β1 concur in inducing antiproliferative effects on the Caco‐2 human colon adenocarcinoma cell line , 2005, BioFactors.
[50] A. Gentilini,et al. 4-Hydroxynonenal as a selective pro-fibrogenic stimulus for activated human hepatic stellate cells. , 2004, Journal of hepatology.
[51] I. Fabregat,et al. Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-beta in fetal rat hepatocytes. , 2004, Free radical biology & medicine.
[52] A. Galloway,et al. Transforming growth factor-beta1 induces apoptosis in vascular endothelial cells by activation of mitogen-activated protein kinase. , 2002, Surgery.
[53] B. Vogelstein,et al. Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line. , 2001, Cancer research.
[54] G. Poli,et al. Oxidative damage and transforming growth factor beta 1 expression in pretumoral and tumoral lesions of human intestine. , 1997, Free radical biology & medicine.
[55] G. Poli,et al. Oxidative damage and fibrogenesis. , 1997, Free radical biology & medicine.
[56] H. Esterbauer,et al. Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes. , 1991, Free radical biology & medicine.