Stable and unstable transgene integration sites in the human genome: extinction of the Green Fluorescent Protein transgene in K562 cells.

[1]  R. Hoffman,et al.  Embryonic-fetal erythroid characteristics of a human leukemic cell line. , 1980, Proceedings of the National Academy of Sciences of the United States of America.

[2]  D. Tuan,et al.  The "beta-like-globin" gene domain in human erythroid cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[3]  J. Yee,et al.  Factors affecting long-term stability of Moloney murine leukemia virus-based vectors. , 1989, Virology.

[4]  N. Martin,et al.  A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice. , 1989, Genes & development.

[5]  Y. Kan,et al.  Human beta-globin gene expression in transgenic mice is enhanced by a distant DNase I hypersensitive site. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[6]  D. Tuan,et al.  An erythroid-specific, developmental-stage-independent enhancer far upstream of the human "beta-like globin" genes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[7]  A. Nienhuis,et al.  Tandem AP-1-binding sites within the human beta-globin dominant control region function as an inducible enhancer in erythroid cells. , 1990, Genes & development.

[8]  T. Palmer,et al.  Genetically modified skin fibroblasts persist long after transplantation but gradually inactivate introduced genes. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[9]  D. Williams,et al.  Retroviral gene transfer of human adenosine deaminase in murine hematopoietic cells: effect of selectable marker sequences on long-term expression. , 1991, Blood.

[10]  T. Ley,et al.  Structure and function of the murine β-globin locus control region 5′ HS-3 , 1992 .

[11]  G. Felsenfeld,et al.  A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila , 1993, Cell.

[12]  Webb Miller,et al.  Comparative analysis of the locus control region of the rabbit β-like globin gene cluster: HS3 increases transient expression of an embryonic ε-globin gene , 1993 .

[13]  F. Grosveld,et al.  The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region. , 1993, The EMBO journal.

[14]  J. Yu,et al.  A 5' beta-globin matrix-attachment region and the polyoma enhancer together confer position-independent transcription. , 1994, Gene.

[15]  G. Stamatoyannopoulos,et al.  Hypersensitive site 5 of the human beta locus control region functions as a chromatin insulator. , 1994, Blood.

[16]  M. Chalfie,et al.  Green fluorescent protein as a marker for gene expression. , 1994, Science.

[17]  F. Grosveld,et al.  Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[18]  D. Tuan,et al.  Dynamic changes in the locus control region of erythroid progenitor cells demonstrated by polymerase chain reaction. , 1996, Blood.

[19]  C. von Kalle,et al.  Long-term persistence of canine hematopoietic cells genetically marked by retrovirus vectors. , 1996, Human gene therapy.

[20]  Richard J Smeyne,et al.  Retroviral-mediated transfer of the green fluorescent protein gene into murine hematopoietic cells facilitates scoring and selection of transduced progenitors in vitro and identification of genetically modified cells in vivo. , 1997, Blood.

[21]  M. Farrell,et al.  GATA-1 expression pattern can be recapitulated in living transgenic zebrafish using GFP reporter gene. , 1997, Development.

[22]  D. Tuan,et al.  Modulatory subdomains of the HS2 enhancer differentially regulate enhancer activity in erythroid cells at different developmental stages. , 1997, Blood cells, molecules & diseases.

[23]  J. Miller,et al.  Long-term, stable expression of green fluorescent protein in mammalian cells. , 1997, Biochemical and biophysical research communications.

[24]  G. Wagemaker,et al.  Green fluorescent protein variants as markers of retroviral-mediated gene transfer in primary hematopoietic cells and cell lines. , 1997, Biochemical and biophysical research communications.

[25]  J. Briones,et al.  High-titer retroviral vectors containing the enhanced green fluorescent protein gene for efficient expression in hematopoietic cells. , 1997, Blood.

[26]  G. Wagemaker,et al.  Enhanced green fluorescent protein as selectable marker of retroviral-mediated gene transfer in immature hematopoietic bone marrow cells. , 1997, Blood.

[27]  A. Nienhuis,et al.  Use of the green fluorescent protein as a marker to identify and track genetically modified hematopoietic cells , 1998, Nature Medicine.

[28]  R. Ashmun,et al.  In vivo selection of retrovirally transduced hematopoietic stem cells , 1998, Nature Medicine.

[29]  R. Bhatnagar,et al.  Stable expression of green fluorescent protein after liposomal transfection of K562 cells without selective growth conditions. , 1999, BioTechniques.