Mitochondrial GRIM-19 loss in parietal cells promotes spasmolytic polypeptide-expressing metaplasia through NLR family pyrin domain-containing 3 (NLRP3)-mediated IL-33 activation via a reactive oxygen species (ROS) -NRF2- Heme oxygenase-1(HO-1)-NF-кB axis.

[1]  Yang Sun,et al.  A novel function of NLRP3 independent of inflammasome as a key transcription factor of IL-33 in epithelial cells of atopic dermatitis , 2021, Cell Death & Disease.

[2]  Xiaohui Xu,et al.  Antidiabetic DPP-4 Inhibitors Reprogram Tumor Microenvironment That Facilitates Murine Breast Cancer Metastasis Through Interaction With Cancer Cells via a ROS–NF-кB–NLRP3 Axis , 2021, Frontiers in Oncology.

[3]  J. Gisbert,et al.  Follow-Up Study Confirms the Presence of Gastric Cancer DNA Methylation Hallmarks in High-Risk Precursor Lesions , 2021, Cancers.

[4]  Meihua Yang,et al.  Antidiabetic Agent DPP-4i Facilitates Murine Breast Cancer Metastasis by Oncogenic ROS-NRF2-HO-1 Axis via a Positive NRF2-HO-1 Feedback Loop , 2021, Frontiers in Oncology.

[5]  R. Li,et al.  [Mechanism of hepatocyte mitochondrial NDUFA13 deficiency-induced liver fibrogenesis: the role of abnormal hepatic stellate cell activation]. , 2021, Nan fang yi ke da xue xue bao = Journal of Southern Medical University.

[6]  Xiaohui Xu,et al.  [Pathogenic role of NDUFA13 inactivation in spontaneous hepatitis in mice and the mechanism]. , 2021, Nan fang yi ke da xue xue bao = Journal of Southern Medical University.

[7]  J. Mills,et al.  IL-33 triggers early eosinophil-dependent events leading to metaplasia in a chronic model of gastritis-prone mice. , 2020, Gastroenterology.

[8]  Meihua Yang,et al.  Mitochondrial GRIM-19 deficiency facilitates gastric cancer metastasis through oncogenic ROS-NRF2-HO-1 axis via a NRF2-HO-1 loop , 2020, Gastric Cancer.

[9]  J. Mills,et al.  Proliferation and Differentiation of Gastric Mucous Neck and Chief Cells During Homeostasis and Injury-induced Metaplasia. , 2020, Gastroenterology.

[10]  M. Hibbs,et al.  IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization , 2019, Nature Communications.

[11]  Meihua Yang,et al.  MicroRNA-7 as a potential therapeutic target for aberrant NF-κB-driven distant metastasis of gastric cancer , 2019, Journal of experimental & clinical cancer research : CR.

[12]  Xiaodi Zhao,et al.  MicroRNA-92a-1–5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia , 2019, Gut.

[13]  J. Goldenring,et al.  Injury, repair, inflammation and metaplasia in the stomach , 2018, The Journal of physiology.

[14]  J. Girard,et al.  Interleukin‐33 (IL‐33): A nuclear cytokine from the IL‐1 family , 2018, Immunological reviews.

[15]  J. Mills,et al.  Metaplastic Cells in the Stomach Arise, Independently of Stem Cells, via Dedifferentiation or Transdifferentiation of Chief Cells. , 2017, Gastroenterology.

[16]  J. Mills,et al.  Targeted Apoptosis of Parietal Cells Is Insufficient to Induce Metaplasia in Stomach. , 2017, Gastroenterology.

[17]  S. Levy,et al.  A signalling cascade of IL-33 to IL-13 regulates metaplasia in the mouse stomach , 2017, Gut.

[18]  Lihua Song,et al.  Mitochondrial GRIM-19 as a potential therapeutic target for STAT3-dependent carcinogenesis of gastric cancer , 2016, Oncotarget.

[19]  A. Jemal,et al.  Cancer statistics in China, 2015 , 2016, CA: a cancer journal for clinicians.

[20]  Seamus J. Martin,et al.  Proteolytic Processing of Interleukin-1 Family Cytokines: Variations on a Common Theme. , 2015, Immunity.

[21]  S. Maeda,et al.  Helicobacter pylori-Induced Signaling Pathways Contribute to Intestinal Metaplasia and Gastric Carcinogenesis , 2015, BioMed research international.

[22]  E. Elinav,et al.  Inflammation-induced cancer: crosstalk between tumours, immune cells and microorganisms , 2013, Nature Reviews Cancer.

[23]  G. Fiskum,et al.  Monoallelic loss of tumor suppressor GRIM-19 promotes tumorigenesis in mice , 2013, Proceedings of the National Academy of Sciences.

[24]  L. Cai,et al.  Expression and clinical significance of GRIM-19 in lung cancer , 2012, Medical Oncology.

[25]  B. Monsarrat,et al.  IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G , 2012, Proceedings of the National Academy of Sciences.

[26]  Yi Huang,et al.  Depletion of OLFM4 gene inhibits cell growth and increases sensitization to hydrogen peroxide and tumor necrosis factor-alpha induced-apoptosis in gastric cancer cells , 2012, Journal of Biomedical Science.

[27]  A. Hao,et al.  Downregulation of GRIM‐19 promotes growth and migration of human glioma cells , 2011, Cancer science.

[28]  Yi Huang,et al.  Upregulation of the GRIM-19 gene suppresses invasion and metastasis of human gastric cancer SGC-7901 cell line. , 2010, Experimental cell research.

[29]  J. Mills,et al.  Spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia: time for reevaluation of metaplasias and the origins of gastric cancer. , 2010, Gastroenterology.

[30]  K. Nam,et al.  Oxyntic atrophy, metaplasia, and gastric cancer. , 2010, Progress in molecular biology and translational science.

[31]  C. Gabay,et al.  Interleukin-33 Is Biologically Active Independently of Caspase-1 Cleavage* , 2009, The Journal of Biological Chemistry.

[32]  J. Goldenring,et al.  Current understanding of SPEM and its standing in the preneoplastic process , 2009, Gastric Cancer.

[33]  D. Lawrence,et al.  Induction of IL‐33 expression and activity in central nervous system glia , 2008, Journal of leukocyte biology.

[34]  Xinmin Cao,et al.  GRIM-19 is essential for maintenance of mitochondrial membrane potential. , 2008, Molecular biology of the cell.

[35]  Q. Zeng,et al.  GRIM-19, a Cell Death Regulatory Protein, Is Essential for Assembly and Function of Mitochondrial Complex I , 2004, Molecular and Cellular Biology.

[36]  S. Roy,et al.  The cell death regulator GRIM-19 is an inhibitor of signal transducer and activator of transcription 3 , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[37]  Guochang Huang,et al.  GRIM‐19, a death‐regulatory gene product, suppresses Stat3 activity via functional interaction , 2003, The EMBO journal.

[38]  P. Shapiro,et al.  Identification of GRIM-19, a Novel Cell Death-regulatory Gene Induced by the Interferon-β and Retinoic Acid Combination, Using a Genetic Approach* , 2000, The Journal of Biological Chemistry.

[39]  E. Borden,et al.  Synergistic antitumor effects of a combination of interferons and retinoic acid on human tumor cells in vitro and in vivo. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.

[40]  P. Correa,et al.  Human gastric carcinogenesis: a multistep and multifactorial process--First American Cancer Society Award Lecture on Cancer Epidemiology and Prevention. , 1992, Cancer research.