ACE2 polymorphisms impact COVID-19 severity in obese patients

[1]  N. Soares,et al.  N6-Acetyl-L-Lysine and p-Cresol as Key Metabolites in the Pathogenesis of COVID-19 in Obese Patients , 2022, Frontiers in Immunology.

[2]  N. Firouzabadi,et al.  SNPs of ACE1 (rs4343) and ACE2 (rs2285666) genes are linked to SARS-CoV-2 infection but not with the severity of disease , 2022, Virology journal.

[3]  E. Zorio,et al.  Polymorphisms in ACE, ACE2, AGTR1 genes and severity of COVID-19 disease , 2022, PloS one.

[4]  S. Ganesan,et al.  COVID-19 Crisis Management: Lessons From the United Arab Emirates Leaders , 2021, Frontiers in Public Health.

[5]  I. A. Moonesar,et al.  UAE efforts in promoting COVID-19 vaccination and building vaccine confidence , 2021, Vaccine.

[6]  Nan Wang,et al.  Obesity and severe coronavirus disease 2019: molecular mechanisms, paths forward, and therapeutic opportunities , 2021, Theranostics.

[7]  A. Tabarraei,et al.  Human gene polymorphisms and their possible impact on the clinical outcome of SARS-CoV-2 infection , 2021, Archives of Virology.

[8]  Sepehr Abdolahi,et al.  Investigating the ACE2 polymorphisms in COVID‐19 susceptibility: An in silico analysis , 2021, Molecular genetics & genomic medicine.

[9]  G. Frühbeck,et al.  Obesity as an adipose tissue dysfunction disease and a risk factor for infections – Covid-19 as a case study , 2021, European Journal of Internal Medicine.

[10]  D. Drucker Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning , 2021, Cell Metabolism.

[11]  H. Akhavan-Niaki,et al.  Comprehensive in silico identification of impacts of ACE2 SNPs on COVID-19 susceptibility in different populations , 2020, Gene Reports.

[12]  S. Hannawi,et al.  Combination of obesity and co-morbidities leads to unfavorable outcomes in COVID-19 patients , 2020, Saudi Journal of Biological Sciences.

[13]  H. Freisling,et al.  Body mass index and risk of COVID-19 diagnosis, hospitalisation, and death: a population-based multi-state cohort analysis including 2,524,926 people in Catalonia, Spain , 2020, medRxiv.

[14]  Alexander Hanbo Li,et al.  A catalog of associations between rare coding variants and COVID-19 outcomes , 2020, medRxiv : the preprint server for health sciences.

[15]  G. Chaubey,et al.  Genetic Association of ACE2 rs2285666 Polymorphism With COVID-19 Spatial Distribution in India , 2020, Frontiers in Genetics.

[16]  M. Woodward,et al.  Obesity as a risk factor for COVID‐19 mortality in women and men in the UK biobank: Comparisons with influenza/pneumonia and coronary heart disease , 2020, Diabetes, obesity & metabolism.

[17]  A. Alsheikh-Ali,et al.  Regulation of Angiotensin- Converting Enzyme 2 in Obesity: Implications for COVID-19 , 2020, Frontiers in physiology.

[18]  M. Kivimäki,et al.  Overweight, obesity, and risk of hospitalization for COVID-19: A community-based cohort study of adults in the United Kingdom , 2020, Proceedings of the National Academy of Sciences.

[19]  Quanlong Jiang,et al.  Individual variation of the SARS‐CoV‐2 receptor ACE2 gene expression and regulation , 2020, Aging cell.

[20]  E. Coto,et al.  Angiotensin-converting enzyme (ACE1, ACE2) gene variants are associated with COVID19 severity depending on the hypertension status. , 2020, medRxiv.

[21]  D. Cummings,et al.  The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature , 2020, medRxiv.

[22]  A. Khayat,et al.  ACE2 polymorphisms as potential players in COVID-19 outcome , 2020, medRxiv.

[23]  G. Lippi,et al.  Obesity and Outcomes in COVID-19: When an Epidemic and Pandemic Collide , 2020, Mayo Clinic Proceedings.

[24]  G. Lin,et al.  Angiotensin‐converting enzyme 2 in severe acute respiratory syndrome coronavirus and SARS‐CoV‐2: A double‐edged sword? , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[25]  A. Mantovani,et al.  ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy , 2020, medRxiv.

[26]  K. Kedzierska,et al.  Back to the Future: Lessons Learned From the 1918 Influenza Pandemic , 2018, Front. Cell. Infect. Microbiol..

[27]  M. Hudgens,et al.  Increased risk of influenza among vaccinated adults who are obese , 2017, International Journal of Obesity.

[28]  H. Qiao,et al.  The ACE2 G8790A Polymorphism: Involvement in Type 2 Diabetes Mellitus Combined with Cerebral Stroke , 2017, Journal of clinical laboratory analysis.

[29]  S. Esposito,et al.  Obesity: impact of infections and response to vaccines , 2016, European Journal of Clinical Microbiology & Infectious Diseases.

[30]  A. B. Hassan,et al.  Diagnostic value of H3F3A mutations in giant cell tumour of bone compared to osteoclast‐rich mimics , 2015, The journal of pathology. Clinical research.

[31]  Mones Abu-Asab,et al.  SARS-Coronavirus Open Reading Frame-9b Suppresses Innate Immunity by Targeting Mitochondria and the MAVS/TRAF3/TRAF6 Signalosome , 2014, The Journal of Immunology.

[32]  Jana Marie Schwarz,et al.  MutationTaster2: mutation prediction for the deep-sequencing age , 2014, Nature Methods.

[33]  Yan-yan Li Lack of Association of ACE2 G8790A Gene Mutation with Essential Hypertension in the Chinese Population: A Meta-Analysis Involving 5260 Subjects , 2012, Front. Physio..

[34]  Helga Thorvaldsdóttir,et al.  Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration , 2012, Briefings Bioinform..

[35]  D. Vugia,et al.  A novel risk factor for a novel virus: obesity and 2009 pandemic influenza A (H1N1). , 2011, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[36]  P. Bork,et al.  A method and server for predicting damaging missense mutations , 2010, Nature Methods.

[37]  K. Reynolds,et al.  Global burden of obesity in 2005 and projections to 2030 , 2008, International Journal of Obesity.

[38]  Sriganesh Madhvanath,et al.  Confidence , 2007, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.

[39]  John L. Sullivan,et al.  Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus , 2003, Nature.

[40]  Steven Henikoff,et al.  SIFT: predicting amino acid changes that affect protein function , 2003, Nucleic Acids Res..

[41]  A. Martí,et al.  Evidences on three relevant obesogenes: MC4R, FTO and PPARγ. Approaches for personalized nutrition. , 2011, Molecular nutrition & food research.