A new hybrid system of DMBR-IVCW, which combines a dynamic membrane bioreactor (DMBR) unit and an integrated vertical-flow constructed wetland (IVCW) unit, was applied to treat domestic sewage. The results showed the total removal efficiencies of DMBR-IVCW system at three different operation conditions were 90.3, 93.3 and 92.6% for COD, 93.0, 89.8 and 85.1% for TN, 85.4, 88.0 and 90.4% for TP, and 93.3, 97.3 and 99.1% for turbidity, respectively. The effluent reaches the Class I of National Discharge Standards for sewage in China (GB8978-1996), and can be directly used for water reclamation and reuse. We found that the DMBR unit had good efficiency on removing COD and turbidity, together with great steady performance to buffer organic loadings and hydraulic shocks, while the IVCW unit acted more like an ecological enhanced treatment for the DMBR unit, removing N, P and other nutrients. This hybrid system coupling the advantages of the both units should provide an effective method for high quality effluent.