Recent advances in trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties.
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[1] Mengsu Yang,et al. Trichosanthin's interfacial interactions with phospholipids: a monolayer study. , 2004, Colloids and surfaces. B, Biointerfaces.
[2] F. Stirpe. Ribosome-inactivating proteins. , 2004, Toxicon : official journal of the International Society on Toxinology.
[3] D. Ouyang,et al. Site-directed PEGylation of trichosanthin retained its anti-HIV activity with reduced potency in vitro. , 2004, Biochemical and biophysical research communications.
[4] P. Shaw,et al. Change in pH-dependent Membrane Insertion Characteristics of Trichosanthin Caused by Deletion of Its Last Seven C-terminal Amino Acid Residues , 2003, Biochemistry (Moscow).
[5] P. Shaw,et al. Trichosanthin Induces Leakage and Membrane Fusion of Liposome , 2003, IUBMB life.
[6] P. Shaw,et al. Substrate binding and catalysis in trichosanthin occur in different sites as revealed by the complex structures of several E85 mutants. , 2003, Protein engineering.
[7] P. Shaw,et al. The structural basis of Trp192 and the C-terminal region in trichosanthin for activity and conformational stability. , 2003, Protein engineering.
[8] W. Chan,et al. Receptor-mediated endocytosis of trichosanthin in choriocarcinoma cells. , 2003, Toxicology.
[9] Roger L. Williams,et al. Structural basis for the interaction of [E160A-E189A]-trichosanthin with adenine. , 2003, Toxicon : official journal of the International Society on Toxinology.
[10] Yong-tang Zheng,et al. Independency of anti-HIV-1 activity from ribosome-inactivating activity of trichosanthin. , 2003, Biochemical and biophysical research communications.
[11] Yong-tang Zheng,et al. Anti‐HIV‐1 property of trichosanthin correlates with its ribosome inactivating activity , 2002, FEBS letters.
[12] J. Yu,et al. Identification of the amino acid residues in trichosanthin crucial for IgE response. , 2002, Biochemical and biophysical research communications.
[13] Y. Gong,et al. Capillary electrophoresis and circular dichroism study of trichosanthin and its mutants. , 2002, Talanta.
[14] S. Sui,et al. Effect of phospholipid on trichosanthin adsorption at the air-water interface. , 2001, Biochimica et biophysica acta.
[15] S. Sui,et al. The interaction of trichosanthin with supported phospholipid membranes studied by surface plasmon resonance. , 2001, Biochimica et biophysica acta.
[16] Y. Gong,et al. Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells. , 2001, The Biochemical journal.
[17] P. Shaw,et al. Trichosanthin interacts with acidic ribosomal proteins P0 and P1 and mitotic checkpoint protein MAD2B. , 2001, European journal of biochemistry.
[18] S. Sui,et al. The membrane insertion of trichosanthin is membrane-surface-pH dependent. , 2000, The Biochemical journal.
[19] T. Ng,et al. The plant ribosome inactivating proteins luffin and saporin are potent inhibitors of HIV‐1 integrase , 2000, FEBS letters.
[20] P. Shaw,et al. Trichosanthin interacts with and enters cells via LDL receptor family members. , 2000, Biochemical and biophysical research communications.
[21] P. Shaw,et al. Engineering of a mini-trichosanthin that has lower antigenicity by deleting its C-terminal amino acid residues. , 2000, Biochemical and biophysical research communications.
[22] Z. Xia,et al. Crystal structures of the complexes of trichosanthin with four substrate analogs and catalytic mechanism of RNA N‐glycosidase , 2000, Proteins.
[23] Ma Hui,et al. Trichosanthin induced calcium-dependent generation of reactive oxygen species in human choriocarcinoma cells. , 2000 .
[24] Y. Pommier,et al. Solution Structure of Anti-HIV-1 and Anti-Tumor Protein MAP30 Structural Insights into Its Multiple Functions , 1999, Cell.
[25] J. Eck,et al. Site-specific mutagenesis of mistletoe lectin: the role of RIP activity in apoptosis. , 1999, Biochemical and biophysical research communications.
[26] L. Yan,et al. Role of Arg163 in the N-glycosidase activity of neo-trichosanthin. , 1999, Protein engineering.
[27] L. Yan,et al. Role of TYR70 in the N-glycosidase activity of neo-trichosanthin. , 1999, Toxicon : official journal of the International Society on Toxinology.
[28] Wei Hu,et al. Anti-HIV Agent Trichosanthin Enhances the Capabilities of Chemokines to Stimulate Chemotaxis and G Protein Activation, and This Is Mediated through Interaction of Trichosanthin and Chemokine Receptors , 1999, The Journal of experimental medicine.
[29] P. Shaw,et al. Reducing the immunogenicity and improving the in vivo activity of trichosanthin by site-directed pegylation. , 1999, Life sciences.
[30] P. Shaw,et al. Lowering of trichosanthin immunogenicity by site-specific coupling to dextran. , 1999, Biochemical pharmacology.
[31] P. Shaw,et al. Site-directed polyethylene glycol modification of trichosanthin: effects on its biological activities, pharmacokinetics, and antigenicity. , 1999, Life sciences.
[32] S. Moestrup,et al. Megalin-mediated endocytosis in renal proximal tubule. , 1998, Renal failure.
[33] S. Tam,et al. Position 120-123, a potential active site of trichosanthin. , 1998, Life sciences.
[34] P. Shaw,et al. The antigenic sites of trichosanthin, a ribosome-inactivating protein with multiple pharmacological properties. , 1997, Life sciences.
[35] P. Shaw,et al. Structure/function relationship study of Tyr14 and Arg22 in trichosanthin, a ribosome-inactivating protein. , 1997, European journal of biochemistry.
[36] T. Meyer,et al. Clinical and pathological course of renal disease in non-insulin-dependent diabetes mellitus: the Pima Indian experience. , 1997, Seminars in nephrology.
[37] Y. Ke,et al. Structure-function relationship of trichosanthin. , 1997, Life sciences.
[38] Qi-chen Huang,et al. Studies on crystal structures, active-centre geometry and depurinating mechanism of two ribosome-inactivating proteins. , 1995, The Biochemical journal.
[39] Y. Tsutsumi,et al. Molecular design of hybrid tumour necrosis factor alpha with polyethylene glycol increases its anti-tumour potency. , 1995, British Journal of Cancer.
[40] P. Shaw,et al. Mouse embryonic development and tumor cell growth under the influence of recombinant trichosanthin (a ribosome inactivating protein) and its muteins. , 1995, Teratogenesis, carcinogenesis, and mutagenesis.
[41] Z. Fu,et al. Structure of trichosanthin at 1.88 Å resolution , 1994, Proteins.
[42] H. Yeung,et al. Structure/function relationship study of Gln156, Glu160 and Glu189 in the active site of trichosanthin. , 1994, European journal of biochemistry.
[43] J. Kahn,et al. Safety, activity, and pharmacokinetics of GLQ223 in patients with AIDS and AIDS-related complex , 1994, Antimicrobial Agents and Chemotherapy.
[44] H. Yeung,et al. Minireview: trichosanthin--a protein with multiple pharmacological properties. , 1994, Life sciences.
[45] S. Wu,et al. Refined structure of trichosanthin at 1.73 A resolution. , 1994, Science in China. Series B, Chemistry, life sciences & earth sciences.
[46] D I Stuart,et al. The N-glycosidase mechanism of ribosome-inactivating proteins implied by crystal structures of alpha-momorcharin. , 1994, Structure.
[47] J. S. Zhang,et al. The mechanism of action of trichosanthin on eukaryotic ribosomes--RNA N-glycosidase activity of the cytotoxin. , 1992, Nucleic acids research.
[48] L. O’Brien,et al. Trichosanthin treatment of HIV‐induced immune dysregulation , 1992, European journal of clinical investigation.
[49] H. Yeung,et al. Increasing the plasma half-life of trichosanthin by coupling to dextran. , 1991, Biochemical pharmacology.
[50] P. Andreasen,et al. Lysosomal degradation of receptor-bound urokinase-type plasminogen activator is enhanced by its inhibitors in human trophoblastic choriocarcinoma cells. , 1990, Cell regulation.
[51] S. Lee-Huang,et al. MAP 30: a new inhibitor of HIV‐1 infection and replication , 1990, FEBS letters.
[52] M. McGrath,et al. GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[53] H. Yeung,et al. Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii. , 1986, Toxicon : official journal of the International Society on Toxinology.
[54] Jin Yc. [Intra-amniotic injection of crystal trichosanthin for induction of labour in second trimester pregnancy]. , 1985 .
[55] F. Davis,et al. Effect of covalent attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase. , 1977, The Journal of biological chemistry.