Chromatographic separation and enantiomeric resolution of flurbiprofen and its major metabolites
暂无分享,去创建一个
[1] F. Jamali,et al. Stereospecific High-Performance Liquid Chromatographic (HPLC) Assay of Flurbiprofen in Biological Specimens , 1988, Pharmaceutical Research.
[2] K. Tatsumi,et al. Stereoselective determination of R,S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid and its taurine conjugates in dog urine by high-performance liquid chromatography. , 1998, Journal of chromatography. B, Biomedical sciences and applications.
[3] J. T. Stewart,et al. HPLC determination of ketoprofen enantiomers in human serum using a nonporous octadecylsilane 1.5 μm column with hydroxypropyl β-cyclodextrin as mobile phase additive , 1998 .
[4] C. Swift,et al. Stereospecific analysis of the major metabolites of ibuprofen in urine by sequential achiral-chiral high-performance liquid chromatography. , 1997, Journal of chromatography. B, Biomedical sciences and applications.
[5] C. Swift,et al. Enantiospecific analysis of ibuprofen by high performance liquid chromatography: Determination of free and total drug enantiomer concentrations in serum and urine , 1997 .
[6] H. Homma,et al. Enantiomeric Separation and Detection of 2-Arylpropionic Acids Derivatized with [(N,N-Dimethylamino)sulfonyl]benzofurazan Reagents on a Modified Cellulose Stationary Phase by High-Performance Liquid Chromatography. , 1997, Analytical chemistry.
[7] N. Davies. Methods of analysis of chiral non-steroidal anti-inflammatory drugs. , 1997, Journal of chromatography. B, Biomedical sciences and applications.
[8] S. Eeckhoudt,et al. Biliary excretion and enterohepatic cycling of R- and S-flurbiprofen in the rat. , 1997, Drug metabolism and disposition: the biological fate of chemicals.
[9] J. T. Stewart,et al. Enantiomeric HPLC separation of selected chiral drugs using native and derivatized β-cyclodextrins as chiral mobile phase additives , 1997 .
[10] F. Cabré,et al. Stereoselective Inhibition of Inducible Cyclooxygenase by Chiral Nonsteroidal Antiinflammatory Drugs , 1996, Journal of clinical pharmacology.
[11] M. Vakily,et al. Pharmacokinetics of tiaprofenic acid in humans: lack of stereoselectivity in plasma using both direct and precolumn derivatization methods. , 1996, Journal of pharmaceutical sciences.
[12] M. Vakily,et al. Rapid, sensitive and direct chiral high-performance liquid chromatographic method for ketoprofen enantiomers. , 1996, Journal of chromatography. B, Biomedical applications.
[13] J. Szejtli,et al. Effect of the degree of substitution of cyclodextrin derivatives on chiral separations by high-performance liquid chromatography and capillary electrophoresis. , 1996, Journal of chromatography. A.
[14] T. Imai,et al. Stereoselective disposition of flurbiprofen from a mutual prodrug with a histamine H2-antagonist to reduce gastrointestinal lesions in the rat. , 1996, Chirality.
[15] Y. Tang. Significance of mobile phase composition in enantioseparation of chiral drugs by HPLC on a cellulose-based chiral stationary phase. , 1996, Chirality.
[16] B. Bannwarth,et al. Simultaneous Measurement of Flurbiprofen, Ibuprofen, and Ketoprofen Enantiomer Concentrations in Plasma Using L-Leucinamide as the Chiral Coupling Component , 1995 .
[17] R. Foster,et al. Stereospecific high-performance liquid chromatographic assay of ketoprofen in human plasma and urine. , 1995, Journal of chromatography. B, Biomedical applications.
[18] K. Luyben,et al. Effect of the degree of substitution of (2-hydroxy)propyl-β-cyclodextrin on the enantioseparation of organic acids by capillary electrophoresis , 1994 .
[19] J. X. Vries,et al. The Analysis of Ibuprofen Enantiomers in Human Plasma and Urine by High-Performance Liquid Chromatography on an α1-Acid Glycoprotein Chiral Stationary Phase , 1994 .
[20] J. Hermansson,et al. Dynamic modification of the chiral bonding properties of a CHIRAL-AGP column by organic and inorganic additives: Separation of enantiomers of anti-inflammatory drugs , 1994 .
[21] J. Lötsch,et al. Stereoselective disposition of flurbiprofen in healthy subjects following administration of the single enantiomers. , 1994, British journal of clinical pharmacology.
[22] M. Yamazaki,et al. Resolution and sensitive detection of carboxylic acid enantiomers using fluorescent chiral derivatization reagents by high-performance liquid chromatography , 1994 .
[23] J. Gal,et al. Enantiospecific drug analysis via the ortho-phthalaldehyde/homochiral thiol derivatization method. , 1993, Journal of chromatography.
[24] G. Geisslinger,et al. Variability of inversion of (R)-flurbiprofen in different species. , 1992, Journal of pharmaceutical sciences.
[25] H. Aboul‐Enein,et al. Simple Chiral Liquid Chromatographic Separation of Flurbiprofen Enantiomers in Biological Fluids , 1992 .
[26] S. Hansen,et al. Simultaneous determination of (R)- and (S)-naproxen and (R)- and (S)-6-O-desmethylnaproxen by high-performance liquid chromatography on a Chiral-AGP column. , 1992, Journal of chromatography.
[27] G. Geisslinger,et al. Stereoselective high-performance liquid chromatographic determination of flurbiprofen in human plasma. , 1992, Journal of chromatography.
[28] A. Olsson,et al. Liquid chromatographic determination of the enantiomers of ibuprofen in plasma using a chiral AGP column. , 1991, Journal of chromatography.
[29] I. Wainer,et al. Stereochemical resolution of enantiomeric 2-aryl propionic acid non-steroidal anti-inflammatory drugs on a human serum albumin based high-performance liquid chromatographic chiral stationary phase , 1991 .
[30] L. Aarons,et al. The pharmacokinetics of the enantiomers of flurbiprofen in patients with rheumatoid arthritis. , 1991, British journal of clinical pharmacology.
[31] J. Hermansson,et al. Separation of the enantiomers of β-receptor blocking agents and other cationic drugs using a CHIRAL-AGP® column , 1990 .
[32] R. Day,et al. Stereoselective disposition of ibuprofen and flurbiprofen in rats. , 1990, Chirality.
[33] G. Geisslinger,et al. Stereoselective high-performance liquid chromatographic determination of ketoprofen, ibuprofen and fenoprofen in plasma using a chiral alpha 1-acid glycoprotein column. , 1990, Journal of chromatography.
[34] K. Hatada,et al. Direct chromatographic separation of 2‐arylpropionic acid enantiomers using tris(3,5‐dimethylphenylcarbamate)s of cellulose and amylose as chiral stationary phases , 1989 .
[35] S. Allenmark,et al. Optical resolution of some biologically active compounds by chiral liquid chromatography on BSA-silica (resolvosil) columns , 1989 .
[36] S. Hall,et al. High-performance liquid chromatographic analysis of the enantiomers of flurbiprofen and its metabolites in plasma and urine. , 1989, Journal of chromatography.
[37] E. Mutschler,et al. (-)-(S)-flunoxaprofen and (-)-(S)-naproxen isocyanate: two new fluorescent chiral derivatizing agents for an enantiospecific determination of primary and secondary amines. , 1989, Chirality.
[38] A. Northage,et al. Chromatographic approaches to the quality control of chiral propionate anti-inflammatory drugs and herbicides. , 1989, Journal of chromatography.
[39] K. Stoschitzky,et al. Enantioselective drug monitoring of (R)- and (S)- propranolol in human plasma via derivatization with optically active (R,R)-O,O-diacetyl tartaric acid anhydride. , 1989, Journal of chromatography.
[40] J. Wagner,et al. Pharmacokinetics of flurbiprofen in man. I. Area/dose relationships. , 1987, Biopharmaceutics & drug disposition.
[41] D. McDaniel,et al. Resolution of α-arylacetic acid enantiomers on two chiral stationary phases , 1987 .
[42] H. Spahn. Formation of diastereomeric derivatives of 2-arylpropionic acids using L-leucinamide. , 1987, Journal of chromatography.
[43] T. Miyakawa,et al. Application of an ovomucoid-conjugated column for the optical resolution of some pharmaceutically important compounds. , 1987, Journal of chromatography.
[44] J. Hermansson,et al. Direct liquid chromatographic resolution of acidic drugs using a chiral α1-acid glycoprotein column (Enantiopac®) , 1986 .
[45] N. Singh,et al. Gas chromatographic separation of optically active anti-inflammatory 2-arylpropionic acids using (+)- or (-)-amphetamine as derivatizing reagent. , 1986, Journal of chromatography.
[46] B. Testa,et al. High-performance liquid chromatographic separation of the enantiomers of anti-inflammatory 2-arylpropionates: suitability of the method for in vitro metabolic studies. , 1984, Journal of chromatography.
[47] P. C. Risdall,et al. The disposition and metabolism of flurbiprofen in several species including man. , 1978, Xenobiotica; the fate of foreign compounds in biological systems.