New fiber optic sensor for ambulatory entero-gastric reflux detection

The problem of entero-gastric reflux is clinically relevant and none of the presently available techniques for its detection is satisfactory. Therefore, a portable fiber optic system for ambulatory reflux assessment has been conceived and developed. Two light emitting diodes (for signal and reference) and a suitable electronic circuit for signal processing are associated with a plastic fiber optic bundle. The working principle of the system is based on the characteristic absorption of bilirubin and bile around 450 nm. In-vitro results have shown good accuracy, linearity, and stability in the measurements of the fiber optic system. In-vivo results are promising.