Chemoresistance: Impact of Nuclear Factor (NF)-κB Inhibition by Small Interfering RNA
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[1] R. Gaynor,et al. Enhanced Chemosensitivity to Irinotecan by RNA Interference-Mediated Down-Regulation of the Nuclear Factor-κB p65 Subunit , 2004, Clinical Cancer Research.
[2] M. Cortés,et al. ATM and the Catalytic Subunit of DNA-Dependent Protein Kinase Activate NF-κB through a Common MEK/Extracellular Signal-Regulated Kinase/p90rsk Signaling Pathway in Response to Distinct Forms of DNA Damage , 2004, Molecular and Cellular Biology.
[3] Alan M Gewirtz,et al. Progress in the Development of Nucleic Acids Therapeutics for Cancer , 2004, Cancer biology & therapy.
[4] Richard Pazdur,et al. Velcade: U.S. FDA approval for the treatment of multiple myeloma progressing on prior therapy. , 2003, The oncologist.
[5] I. Verma,et al. IκB Kinase-Independent IκBα Degradation Pathway: Functional NF-κB Activity and Implications for Cancer Therapy , 2003, Molecular and Cellular Biology.
[6] Yang Shi,et al. Small RNA: can RNA interference be exploited for therapy? , 2003, The Lancet.
[7] A. Hoffmann,et al. CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response , 2003 .
[8] R. Schmid,et al. Mitogenic and antiapoptotic role of constitutive NF‐κB/Rel activity in pancreatic cancer , 2003, International journal of cancer.
[9] N. Perkins,et al. p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor , 2003 .
[10] Bart Barlogie,et al. A phase 2 study of bortezomib in relapsed, refractory myeloma. , 2003, The New England journal of medicine.
[11] J. Adams. Potential for proteasome inhibition in the treatment of cancer. , 2003, Drug discovery today.
[12] W. Zong,et al. Mechanisms of constitutive NF‐κB activation in human prostate cancer cells , 2002, The Prostate.
[13] M. Karin,et al. Missing Pieces in the NF-κB Puzzle , 2002, Cell.
[14] Michael Karin,et al. NF-κB in cancer: from innocent bystander to major culprit , 2002, Nature Reviews Cancer.
[15] Ulrich Siebenlist,et al. Constitutive Nuclear Factor κB Activity Is Required for Survival of Activated B Cell–like Diffuse Large B Cell Lymphoma Cells , 2001, The Journal of experimental medicine.
[16] A. Pardee,et al. The nuclear factor kappa B (NF-κB): A potential therapeutic target for estrogen receptor negative breast cancers , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[17] D. S. Lind,et al. Nuclear factor-κB is upregulated in colorectal cancer , 2001 .
[18] Jingqing Yang,et al. Constitutive IκB Kinase Activity Correlates with Nuclear Factor-κB Activation in Human Melanoma Cells , 2001 .
[19] J. Cusack,et al. Inducible chemoresistance to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothe cin (CPT-11) in colorectal cancer cells and a xenograft model is overcome by inhibition of nuclear factor-kappaB activation. , 2000, Cancer research.
[20] C. Van Waes,et al. The host environment promotes the constitutive activation of nuclear factor-kappaB and proinflammatory cytokine expression during metastatic tumor progression of murine squamous cell carcinoma. , 1999, Cancer research.
[21] J. Cusack,et al. Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB , 1999, Nature Medicine.
[22] G. Sledge,et al. Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth , 1997, Molecular and cellular biology.
[23] Marty W. Mayo,et al. TNF- and Cancer Therapy-Induced Apoptosis: Potentiation by Inhibition of NF-κB , 1996, Science.
[24] Y. Oshika,et al. P-glycoprotein-mediated acquired multidrug resistance of human lung cancer cells in vivo. , 1996, British Journal of Cancer.
[25] M. Read,et al. Enhanced Chemosensitivity to Irinotecan by RNA Interference-Mediated Down-Regulation of the NF-B p 65 Subunit , 2004 .
[26] Michael Karin,et al. The IKK NF-kappa B system: a treasure trove for drug development. , 2004, Nature reviews. Drug discovery.
[27] Douglas B. Evans,et al. Function of Nuclear Factor κB in Pancreatic Cancer Metastasis , 2003 .
[28] Céline Gélinas,et al. To be, or not to be: NF-kappaB is the answer--role of Rel/NF-kappaB in the regulation of apoptosis. , 2003, Oncogene.
[29] Douglas B. Evans,et al. Function of nuclear factor kappaB in pancreatic cancer metastasis. , 2003, Clinical cancer research : an official journal of the American Association for Cancer Research.
[30] N. Perkins,et al. p53- and Mdm2-independent repression of NF-kappa B transactivation by the ARF tumor suppressor. , 2003, Molecular cell.
[31] A. Hoffmann,et al. CK2 Is a C-Terminal IkappaB Kinase Responsible for NF-kappaB Activation during the UV Response. , 2003, Molecular cell.
[32] Michael Karin,et al. NF-kappaB in cancer: from innocent bystander to major culprit. , 2002, Nature reviews. Cancer.
[33] S. Alkan,et al. Analysis of expression of nuclear factor kappa B (NF-kappa B) in multiple myeloma: downregulation of NF-kappa B induces apoptosis. , 2001, British journal of haematology.
[34] A. Richmond,et al. Constitutive IkappaB kinase activity correlates with nuclear factor-kappaB activation in human melanoma cells. , 2001, Cancer research.
[35] A. Pardee,et al. The nuclear factor kappa B (NF-kappa B): a potential therapeutic target for estrogen receptor negative breast cancers. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[36] M J May,et al. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. , 1998, Annual review of immunology.
[37] C. Y. Wang,et al. TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB. , 1996, Science.