Cost-effectiveness of short-term tests for carcinogenicity

Most chemicals to which we are exposed are not properly tested for carcinogenicity. The latest methods of in vitro testing provide a way of screening with sufficient accuracy to remedy this situation.

[1]  V. Dunkel,et al.  Reliability of the hepatocyte primary culture/DNA repair test in testing of coded carcinogens and noncarcinogens. , 1982, Mutation research.

[2]  J. Ashby,et al.  Evaluation of short-term tests for carcinogens : report of the international collaborative program , 1981 .

[3]  J H Weisburger,et al.  Carcinogen testing: current problems and new approaches. , 1981, Science.

[4]  I. Purchase,et al.  An appraisal of predictive tests for carcinogenicity , 1982 .

[5]  H S Rosenkranz,et al.  Application of the carcinogenicity prediction and battery selection (CPBS) method to the Gene-Tox data base. , 1985, Mutation research.

[6]  D. W. Roncek,et al.  Discrete Discriminant Analysis. , 1979 .

[7]  Lester Lave,et al.  The Strategy of Social Regulation , 1981 .

[8]  B. Ames,et al.  Identifying environmental chemicals causing mutations and cancer. , 1979, Science.

[9]  D G Hoel,et al.  Implication of nonlinear kinetics on risk estimation in carcinogenesis. , 1983, Science.

[10]  C R Gerber,et al.  Identification, characterization, and control of potential human carcinogens: a framework for Federal decision-making. , 1980, Journal of the National Cancer Institute.

[11]  Lester B. Lave,et al.  A Model for Selecting Short-Term Tests of Carcinogenicity , 1983 .

[12]  D G Hoel,et al.  Fundamental carcinogenic processes and their implications for low dose risk assessment. , 1976, Cancer research.

[13]  S. Stasiewicz,et al.  Chemicals showing no evidence of carcinogenicity in long-term, two-species rodent studies: the need for short-term test data. , 1984, Environmental mutagenesis.

[14]  G. Omenn Predictive identification of hypersusceptible individuals. , 1982, Journal of occupational medicine. : official publication of the Industrial Medical Association.

[15]  H S Rosenkranz,et al.  The carcinogenicity prediction and battery selection (CPBS) method: a Bayesian approach. , 1985, Mutation research.