The use of interpleural analgesia using bupivacaine for pain relief in advanced cancer

The use of interpleural analgesia is described in six patients with a variety of advanced malignancies suffering from pain uncontrolled by opioids. The benefits and complications of the technique are discussed including management of the catheters at home and the measurement of plasma bupivacaine concentrations. Interpleural analgesia can provide good analgesia in a small, selected population of patients with otherwise uncontrolled pain of malignant origin.

[1]  M. Fallon,et al.  ABC of palliative care: Principles of palliative care and pain control , 1997, BMJ.

[2]  D. P. Myers,et al.  Interpleural analgesia for the treatment of severe cancer pain in terminally ill patients. , 1993, Journal of pain and symptom management.

[3]  K. Burn,et al.  Audit of neural blockade for palliative care patients in an acute unit , 1993, Palliative medicine.

[4]  F. Vidal,et al.  Interpleural analgesia through a DuPen catheter for lung cancer pain , 1992, Cancer.

[5]  F. Vidal,et al.  Totally Implantable Interpleural Analgesia in Cancer Pain , 1992, Regional Anesthesia & Pain Medicine.

[6]  C. Dionne.  Tumour invasion of the brachial plexus: management of pain with intrapleural analgesia , 1992, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[7]  P. Steen,et al.  Side effects and complications related to interpleural analgesia: an update , 1990, Acta anaesthesiologica Scandinavica.

[8]  T. Oh,et al.  Effect of adrenaline on venous plasma concentrations of bupivacaine after interpleural administration. , 1990, British journal of anaesthesia.

[9]  W. Mcilvaine,et al.  Interpleural Analgesia in the Treatment of Severe Thoracic Postherpetic Neuralgia , 1990, Regional Anesthesia & Pain Medicine.

[10]  J. Hammon,et al.  Intrapleural analgesia for post-thoracotomy pain and blood levels of bupivacaine following intrapleural injection. , 1989, Canadian journal of anaesthesia = Journal canadien d'anesthesie.

[11]  T. Stokke,et al.  Interpleural analgesia in treatment of upper extremity reflex sympathetic dystrophy. , 1989, Anesthesia and Analgesia.

[12]  S. Waldman,et al.  Subcutaneous tunneled intrapleural catheters in the long-term relief of right upper quadrant pain of malignant origin. , 1989, Journal of pain and symptom management.

[13]  S. Fineman.  Long-term post-thoracotomy cancer pain management with interpleural bupivacaine. , 1989, Anesthesia and analgesia.

[14]  J. Hammon,et al.  Intrapleural analgesia for postthoracotomy pain and blood levels of bupivacaine following intrapleural injection , 1989 .

[15]  A. Rocco,et al.  Continuous subpleural-paravertebral block in acute thoracic herpes zoster. , 1988, Anesthesia and analgesia.

[16]  A. Winnie,et al.  Interpleural catheter analgesia for pancreatic pain. , 1988, Anesthesia and Analgesia.

[17]  J. Seltzer,et al.  Intrapleural bupivacaine--a kinetic and dynamic evaluation. , 1987, Anesthesiology.

[18]  G. Hedenstierna,et al.  Postoperative analgesia with intrapleural administration of bupivacaine‐adrenaline , 1987, Acta anaesthesiologica Scandinavica.

[19]  M. Wood.  Plasma Drug Binding: Implications for Anesthesiologists , 1986, Anesthesia and analgesia.

[20]  G. Tucker.  PHARAMACOKINETICS OF LOCAL ANAESTHETICS , 1986 .

[21]  K. E. Strømskag,et al.  Interpleural Catheter in the Management of Postoperative Pain A Preliminary Report , 1986, Regional Anesthesia & Pain Medicine.

[22]  G. Tucker,et al.  Clinical Pharmacokinetics of Local Anaesthetics , 1979, Clinical pharmacokinetics.

[23]  G. Tucker.  Pharmacokinetics of local anaesthetics. , 1986, British journal of anaesthesia.