MitoCeption as a new tool to assess the effects of mesenchymal stem/stromal cell mitochondria on cancer cell metabolism and function

[1]  B. Alman,et al.  Disruption of Crosstalk between Mesenchymal Stromal and Tumor Cells in Bone Marrow as a Therapeutic Target to Prevent Metastatic Bone Disease , 2014, Journal of cellular physiology.

[2]  Prashant Mishra,et al.  Mitochondrial dynamics and inheritance during cell division, development and disease , 2014, Nature Reviews Molecular Cell Biology.

[3]  R. Kalluri,et al.  PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation to promote metastasis , 2014, Nature Cell Biology.

[4]  R. Weinberg,et al.  The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis , 2014, Nature Cell Biology.

[5]  Jian Lu,et al.  Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals , 2014, Proceedings of the National Academy of Sciences.

[6]  N. Chandel.  Mitochondria as signaling organelles , 2014, BMC Biology.

[7]  Chawnshang Chang,et al.  Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signaling , 2014, Oncogene.

[8]  M. Nireekshan Kumar,et al.  Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy , 2014, The EMBO journal.

[9]  R. Christensen,et al.  Mesenchymal stem cells, cancer challenges and new directions. , 2014, European journal of cancer.

[10]  D. Kami,et al.  Direct human mitochondrial transfer: a novel concept based on the endosymbiotic theory. , 2014, Transplantation proceedings.

[11]  Huixia Lu,et al.  Mesenchymal stem cells rescue injured endothelial cells in an in vitro ischemia-reperfusion model via tunneling nanotube like structure-mediated mitochondrial transfer. , 2014, Microvascular research.

[12]  T. Langer,et al.  Mitochondrial lipid trafficking. , 2014, Trends in cell biology.

[13]  R. Just,et al.  A high-throughput Sanger strategy for human mitochondrial genome sequencing , 2013, BMC Genomics.

[14]  W. Woodward,et al.  Human Omental-Derived Adipose Stem Cells Increase Ovarian Cancer Proliferation, Migration, and Chemoresistance , 2013, PloS one.

[15]  Valentina Gori,et al.  Tumor microenvironment: bone marrow-mesenchymal stem cells as key players. , 2013, Biochimica et biophysica acta.

[16]  M. Hung,et al.  Mesenchymal stem cells promote growth and angiogenesis of tumors in mice , 2013, Oncogene.

[17]  Kenneth J. Pienta,et al.  Recruitment of Mesenchymal Stem Cells Into Prostate Tumors Promotes Metastasis , 2013, Nature Communications.

[18]  S. Rafii,et al.  Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance , 2013, Journal of Translational Medicine.

[19]  R. Bjerkvig,et al.  Mesenchymal stem cell signaling in cancer progression. , 2013, Cancer treatment reviews.

[20]  Douglas B. Cowan,et al.  Transplantation of Autologously‐Derived Mitochondria Protects the Heart from Ischemia‐Reperfusion Injury , 2013, American journal of physiology. Heart and circulatory physiology.

[21]  M. Marazzi,et al.  Mesenchymal Stem/Stromal Cells: A New "Cells as Drugs" Paradigm. Efficacy and Critical Aspects in Cell Therapy , 2013, Current pharmaceutical design.

[22]  L. Otterbein,et al.  Mitochondrial DAMPs Increase Endothelial Permeability through Neutrophil Dependent and Independent Pathways , 2013, PloS one.

[23]  Cole M. Haynes,et al.  Signaling the mitochondrial unfolded protein response. , 2013, Biochimica et biophysica acta.

[24]  M. Richard,et al.  The dual effect of MSCs on tumour growth and tumour angiogenesis , 2013 .

[25]  M. Richard,et al.  The dual effect of mesenchymal stem cells on tumour growth and tumour angiogenesis , 2013, Stem Cell Research & Therapy.

[26]  A. Harris,et al.  How cancer metabolism is tuned for proliferation and vulnerable to disruption , 2012, Nature.

[27]  Vamsi K. Mootha,et al.  Mitochondrial disorders as windows into an ancient organelle , 2012, Nature.

[28]  A. Terzic,et al.  Metabolic plasticity in stem cell homeostasis and differentiation. , 2012, Cell stem cell.

[29]  Lixin Wei,et al.  Mesenchymal Stem Cells in Inflammation Microenvironment Accelerates Hepatocellular Carcinoma Metastasis by Inducing Epithelial-Mesenchymal Transition , 2012, PloS one.

[30]  P. Oliveira,et al.  Mitochondrial remodeling in cancer metabolism and survival: potential for new therapies. , 2012, Biochimica et biophysica acta.

[31]  Armand Keating,et al.  Mesenchymal stromal cells: new directions. , 2012, Cell stem cell.

[32]  H. Haller,et al.  Vascular smooth muscle cells initiate proliferation of mesenchymal stem cells by mitochondrial transfer via tunneling nanotubes. , 2012, Stem cells and development.

[33]  C. Pinkert,et al.  Influence of intergeneric/interspecies mitochondrial injection; parthenogenetic development of bovine oocytes after injection of mitochondria derived from somatic cells. , 2012, The Journal of reproduction and development.

[34]  E. Voest,et al.  The role of mesenchymal stem cells in anti-cancer drug resistance and tumour progression , 2012, British Journal of Cancer.

[35]  D. Rowlands,et al.  Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury , 2012, Nature Medicine.

[36]  J. Nunnari,et al.  Mitochondria: In Sickness and in Health , 2012, Cell.

[37]  C. Zurzolo,et al.  Wiring through tunneling nanotubes – from electrical signals to organelle transfer , 2012, Journal of Cell Science.

[38]  D. Green,et al.  Mitochondria and cell signalling , 2012, Journal of Cell Science.

[39]  P. Overbeek,et al.  Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells. , 2012, Cell metabolism.

[40]  D. Prockop,et al.  Mesenchymal stromal cells protect cancer cells from ROS-induced apoptosis and enhance the Warburg effect by secreting STC1. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

[41]  C. Croce,et al.  Stromal control of cystine metabolism promotes cancer cell survival in chronic lymphocytic leukemia , 2012, Nature Cell Biology.

[42]  F. Sotgia,et al.  Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells , 2011, Cancer biology & therapy.

[43]  R. Medema,et al.  Mesenchymal stem cells induce resistance to chemotherapy through the release of platinum-induced fatty acids. , 2011, Cancer cell.

[44]  P. Lesault,et al.  Human Mesenchymal Stem Cells Reprogram Adult Cardiomyocytes Toward a Progenitor‐Like State Through Partial Cell Fusion and Mitochondria Transfer , 2011, Stem cells.

[45]  B. Lambrecht,et al.  Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation. , 2011, Trends in immunology.

[46]  F. Blanco,et al.  The role of mitochondria in osteoarthritis , 2011, Nature Reviews Rheumatology.

[47]  D. Kaplan,et al.  Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. , 2010, Cancer research.

[48]  D. Banerjee,et al.  Interleukin 6 mediated recruitment of mesenchymal stem cells to the hypoxic tumor milieu. , 2010, Experimental cell research.

[49]  G. Sukhikh,et al.  Cytoplasm and organelle transfer between mesenchymal multipotent stromal cells and renal tubular cells in co-culture. , 2010, Experimental cell research.

[50]  A. Tsirigos,et al.  Ketones and lactate “fuel” tumor growth and metastasis , 2010, Cell cycle.

[51]  L. Wong,et al.  Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids , 2010, Annals of the New York Academy of Sciences.

[52]  R. Youle,et al.  Mechanisms of mitophagy , 2010, Nature Reviews Molecular Cell Biology.

[53]  E. Hodneland,et al.  Selective block of tunneling nanotube (TNT) formation inhibits intercellular organelle transfer between PC12 cells , 2009, FEBS letters.

[54]  E. Hodneland,et al.  Tunneling nanotube (TNT)-like structures facilitate a constitutive, actomyosin-dependent exchange of endocytic organelles between normal rat kidney cells. , 2008, Experimental cell research.

[55]  M. Gustafsson,et al.  Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination. , 2008, Biophysical journal.

[56]  J. Hayashi,et al.  ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis , 2008, Science.

[57]  G. Sukhikh,et al.  Cell-to-cell cross-talk between mesenchymal stem cells and cardiomyocytes in co-culture , 2007, Journal of cellular and molecular medicine.

[58]  Ross Tubo,et al.  Mesenchymal stem cells within tumour stroma promote breast cancer metastasis , 2007, Nature.

[59]  Darwin J. Prockop,et al.  Mitochondrial transfer between cells can rescue aerobic respiration , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[60]  C. Pinkert,et al.  Microinjection of Cytoplasm or Mitochondria Derived from Somatic Cells Affects Parthenogenetic Development of Murine Oocytes1 , 2005, Biology of reproduction.

[61]  J. Sinclair,et al.  Mitochondrial transfer between oocytes: potential applications of mitochondrial donation and the issue of heteroplasmy. , 1998, Human reproduction.

[62]  A. Schapira,et al.  Mitochondrial disorders: an overview. , 1997, Journal of bioenergetics and biomembranes.

[63]  L. Klotz.  New Directions , 1979, The Canadian journal of urology.

[64]  A. Vinokur,et al.  "In Sickness and in Health" , 1990 .

[65]  O. Warburg.  [Origin of cancer cells]. , 1956, Oncologia.

[66]  Warren Bower.  New directions , 1937 .