FoxO is a critical regulator of stem cell maintenance in immortal Hydra

This study has established the role of forkhead box proteins in longevity by exploring the immortal characteristics of hydra which shows no sign of aging and reproductive loss. This study has revealed the role of foxO in early evolution of stem cell and in maintaining stem cell renewal capacity. FoxO has role to play in studying aging process and reduction of immunity functions with future implications for regenerative medicine.