Bone formation by human postnatal bone marrow stromal stem cells is enhanced by telomerase expression

[1]  Chunhui Xu,et al.  Feeder-free growth of undifferentiated human embryonic stem cells , 2001, Nature Biotechnology.

[2]  J. Glowacki,et al.  Age‐related decline in the osteogenic potential of human bone marrow cells cultured in three‐dimensional collagen sponges , 2001, Journal of cellular biochemistry.

[3]  H. Okano,et al.  High-yield selection and extraction of two promoter-defined phenotypes of neural stem cells from the fetal human brain , 2001, Nature Biotechnology.

[4]  Carol W. Greider,et al.  Telomere Dysfunction Increases Mutation Rate and Genomic Instability , 2001, Cell.

[5]  K. Yudoh,et al.  Reconstituting Telomerase Activity Using the Telomerase Catalytic Subunit Prevents the Telomere Shorting and Replicative Senescence in Human Osteoblasts , 2001, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[6]  S. Bruder,et al.  Mesenchymal stem cells: building blocks for molecular medicine in the 21st century. , 2001, Trends in molecular medicine.

[7]  Mara Riminucci,et al.  Bone Marrow Stromal Stem Cells: Nature, Biology, and Potential Applications , 2001, Stem cells.

[8]  Kazutoshi Nozaki,et al.  A biodegradable polymer as a cytokine delivery system for inducing bone formation , 2001, Nature Biotechnology.

[9]  Jiwei Yang,et al.  Telomerized human microvasculature is functional in vivo , 2001, Nature Biotechnology.

[10]  C. Boehm,et al.  Age‐ and gender‐related changes in the cellularity of human bone marrow and the prevalence of osteoblastic progenitors , 2001, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[11]  S. Gronthos,et al.  Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[12]  A. Meunier,et al.  Tissue-engineered bone regeneration , 2000, Nature Biotechnology.

[13]  G. Karsenty,et al.  The osteoblast: a sophisticated fibroblast under central surveillance. , 2000, Science.

[14]  T. Martin,et al.  Therapeutic approaches to bone diseases. , 2000, Science.

[15]  A. Reddi,et al.  Morphogenesis and tissue engineering of bone and cartilage: inductive signals, stem cells, and biomimetic biomaterials. , 2000, Tissue engineering.

[16]  R. McKay,et al.  Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells , 2000, Nature Biotechnology.

[17]  A Boyde,et al.  Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones. , 2000, Journal of biomedical materials research.

[18]  R. DePinho,et al.  Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery. , 2000, Science.

[19]  J. Screen,et al.  Further Characterization of Cells Expressing STRO‐1 in Cultures of Adult Human Bone Marrow Stromal Cells , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[20]  Robert A. Weinberg,et al.  Creation of human tumour cells with defined genetic elements , 1999, Nature.

[21]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[22]  Sandy Chang,et al.  Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice , 1999, Cell.

[23]  S. Gronthos,et al.  Differential Cell Surface Expression of the STRO‐1 and Alkaline Phosphatase Antigens on Discrete Developmental Stages in Primary Cultures of Human Bone Cells , 1999, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[24]  S. Benchimol,et al.  Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span , 1998, Current Biology.

[25]  C. Harley,et al.  Extension of life-span by introduction of telomerase into normal human cells. , 1998, Science.

[26]  D. Benayahu,et al.  Single‐Colony Derived Strains of Human Marrow Stromal Fibroblasts Form Bone After Transplantation In Vivo , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[27]  C B Harley,et al.  Telomerase catalytic subunit homologs from fission yeast and human. , 1997, Science.

[28]  S Tamai,et al.  The Effect of Aging on Bone Formation in Porous Hydroxyapatite: Biochemical and Histological Analysis , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[29]  D. Rowe,et al.  Bone formation in vivo: comparison of osteogenesis by transplanted mouse and human marrow stromal fibroblasts. , 1997, Transplantation.

[30]  T R Hughes,et al.  Reverse transcriptase motifs in the catalytic subunit of telomerase. , 1997, Science.

[31]  D. Prockop Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues , 1997, Science.

[32]  H. Gruber,et al.  Age‐related changes in osteogenic stem cells in mice , 1996, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[33]  D. Broccoli,et al.  Telomerase activity in normal and malignant hematopoietic cells. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[34]  et al.,et al.  The RNA component of human telomerase , 1995, Science.

[35]  J. Gimble,et al.  Bone morphogenetic proteins inhibit adipocyte differentiation by bone marrow stromal cells , 1995, Journal of cellular biochemistry.

[36]  C B Harley,et al.  Specific association of human telomerase activity with immortal cells and cancer. , 1994, Science.

[37]  P. Roholl,et al.  Evidence for a diminished maturation of preosteoblasts into osteoblasts during aging in rats: An ultrastructural analysis , 1994, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[38]  C B Harley,et al.  Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. , 1993, American journal of human genetics.

[39]  C B Harley,et al.  Telomere length predicts replicative capacity of human fibroblasts. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[40]  J. Steitz,et al.  Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. , 1992, The EMBO journal.

[41]  C. Harley,et al.  Telomeres shorten during ageing of human fibroblasts , 1990, Nature.

[42]  E. Blackburn,et al.  A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis , 1989, Nature.

[43]  S. Bruder,et al.  Mesenchymal stem cells : building blocks for molecular medicine in the 21 st century , 2001 .

[44]  P. Hornsby,et al.  Formation of functional tissue from transplanted adrenocortical cells expressing telomerase reverse transcriptase , 2000, Nature Biotechnology.

[45]  R. Faragher,et al.  Telomerase prevents the accelerated cell ageing of Werner syndrome fibroblasts , 2000, Nature Genetics.

[46]  M. White,et al.  Absence of cancer–associated changes in human fibroblasts immortalized with telomerase , 1999, Nature Genetics.

[47]  N. Endo,et al.  Number of osteoprogenitor cells in human bone marrow markedly decreases after skeletal maturation , 1999, Journal of Bone and Mineral Metabolism.

[48]  J. Shay,et al.  Telomerase activity in human germline and embryonic tissues and cells. , 1996, Developmental genetics.