Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion
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P. Navas | G. Stamatoyannopoulos | Qiliang Li | C. Clegg | K. Peterson | A. Rohde | E. Skarpidi | H. Asano | S. Shaw | Sara E. Shaw
[1] A. Mutero,et al. The human beta globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice. , 1997, Blood.
[2] G. Stamatoyannopoulos,et al. Binary transgenic mouse model for studying the trans control of globin gene switching: evidence that GATA-1 is an in vivo repressor of human epsilon gene expression. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[3] J. Strouboulis,et al. Heterochromatin Effects on the Frequency and Duration of LCR-Mediated Gene Transcription , 1996, Cell.
[4] T. Kimbrough,et al. Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[5] T. Ley,et al. Analysis of mice containing a targeted deletion of beta-globin locus control region 5' hypersensitive site 3 , 1996, Molecular and cellular biology.
[6] W. Miller,et al. Role of DNA sequences outside the cores of DNase hypersensitive sites (HSs) in functions of the beta-globin locus control region. Domain opening and synergism between HS2 and HS3. , 1996, The Journal of biological chemistry.
[7] F. Grosveld,et al. A dominant chromatin‐opening activity in 5′ hypersensitive site 3 of the human beta‐globin locus control region. , 1996, The EMBO journal.
[8] J. D. Engel,et al. Synergistic regulation of human beta-globin gene switching by locus control region elements HS3 and HS4. , 1995, Genes & development.
[9] T. Ley,et al. Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus. , 1995, Genes & development.
[10] T. Kimbrough,et al. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[11] Peter Fraser,et al. Transcription complex stability and chromatin dynamics in vivo , 1995, Nature.
[12] J. Stamatoyannopoulos,et al. Position independence and proper developmental control of gamma-globin gene expression require both a 5' locus control region and a downstream sequence element , 1994, Molecular and cellular biology.
[13] Y. Kan,et al. Germ-line transmission and developmental regulation of a 150-kb yeast artificial chromosome containing the human beta-globin locus in transgenic mice. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[14] G. Stamatoyannopoulos,et al. Transgenic mice containing a 248-kb yeast artificial chromosome carrying the human beta-globin locus display proper developmental control of human globin genes. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[15] A. Gnirke,et al. Microinjection of intact 200- to 500-kb fragments of YAC DNA into mammalian cells. , 1993, Genomics.
[16] F. Grosveld,et al. The minimal requirements for activity in transgenic mice of hypersensitive site 3 of the beta globin locus control region. , 1993, The EMBO journal.
[17] F. Grosveld,et al. Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes. , 1993, Genes & development.
[18] J. Strouboulis,et al. Developmental regulation of a complete 70-kb human beta-globin locus in transgenic mice. , 1992, Genes & development.
[19] Y. Kan,et al. Dissection of the enhancer activity of beta-globin 5' DNase I-hypersensitive site 2 in transgenic mice. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[20] G. Felsenfeld,et al. Chromatin as an essential part of the transcriptional mechanim , 1992, Nature.
[21] A. Gnirke,et al. Transfer of yeast artificial chromosomes from yeast to mammalian cells. , 1991, BioEssays : news and reviews in molecular, cellular and developmental biology.
[22] F. Grosveld,et al. Hypersensitive site 4 of the human β globin locus control region , 1991 .
[23] G. Stamatoyannopoulos,et al. Autonomous developmental control of human embryonic globin gene switching in transgenic mice. , 1990, Science.
[24] G. Stamatoyannopoulos,et al. Beta-globin locus activation regions: conservation of organization, structure, and function. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[25] T. Ley,et al. Conservation of the primary structure, organization, and function of the human and mouse beta-globin locus-activating regions. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[26] W. C. Forrester,et al. A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus. , 1990, Genes & development.
[27] F. Grosveld,et al. The beta‐globin dominant control region: hypersensitive site 2. , 1990, The EMBO journal.
[28] F. Grosveld,et al. Detailed analysis of the site 3 region of the human beta‐globin dominant control region. , 1990, The EMBO journal.
[29] F. Grosveld,et al. DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression. , 1990, Nucleic acids research.
[30] B. Alter,et al. Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[31] W. C. Forrester,et al. Molecular analysis of the human beta-globin locus activation region. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[32] F. Grosveld,et al. The β-globin dominant control region activates homologous and heterologous promoters in a tissue-specific manner , 1989, Cell.
[33] N. Martin,et al. A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice. , 1989, Genes & development.
[34] R. Palmiter,et al. DNase I super-hypersensitive sites direct high level erythroid expression of human alpha-, beta- and beta s- globin genes in transgenic mice. , 1989, Progress in clinical and biological research.
[35] M. Vidal,et al. A dominant control region from the human β-globin locus conferring integration site-independent gene expression , 1989, Nature.
[36] G. Kollias,et al. Position-independent, high-level expression of the human β-globin gene in transgenic mice , 1987, Cell.
[37] W. C. Forrester,et al. Evidence for a locus activation region: the formation of developmentally stable hypersensitive sites in globin-expressing hybrids. , 1987, Nucleic acids research.
[38] F. Costantini,et al. A 3' enhancer contributes to the stage-specific expression of the human beta-globin gene. , 1987, Genes & development.
[39] R. Palmiter,et al. Two 3' sequences direct adult erythroid-specific expression of human beta-globin genes in transgenic mice. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[40] G. Kollias,et al. The human β-globin gene contains a downstream developmental specific enhancer , 1987 .
[41] M. Goodman,et al. Globins: a case study in molecular phylogeny. , 1987, Cold Spring Harbor symposia on quantitative biology.
[42] T. Maniatis,et al. Rapid reprogramming of globin gene expression in transient heterokaryons , 1986, Cell.
[43] James T. Elder,et al. A developmentally stable chromatin structure in the human beta-globin gene cluster. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[44] Y. Kan,et al. A distant gene deletion affects beta-globin gene function in an atypical gamma delta beta-thalassemia. , 1985, The Journal of clinical investigation.
[45] D. Tuan,et al. The "beta-like-globin" gene domain in human erythroid cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[46] G. Fink,et al. Eviction and transplacement of mutant genes in yeast. , 1983, Methods in enzymology.
[47] D. Kioussis,et al. β-Globin gene inactivation by DNA translocation in γβ-thalassaemi , 1983, Nature.