Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression
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G. Mills | Han Liang | Y. Tsang | K. Scott | Yumeng Wang | D. Moreno | V. H. Bhavana | Kathleen Kong | T. Dogruluk | Oksana Zagorodna | S. Elsea | Caitlin L. Grzeskowiak | Hengyu Lu | Nicole Villafañe
[1] Icgc,et al. Pan-cancer analysis of whole genomes , 2017, bioRxiv.
[2] Junmin Peng,et al. Regulation of MAGE‐A3/6 by the CRL4‐DCAF12 ubiquitin ligase and nutrient availability , 2019, EMBO reports.
[3] E. Petricoin,et al. Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer , 2019, Nature Medicine.
[4] J. Yap,et al. Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers , 2019, Nature Medicine.
[5] N. Hacohen,et al. Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade , 2018, Cell.
[6] Bin Zhang,et al. Correlation between the high expression levels of cancer-germline genes with clinical characteristics in esophageal squamous cell carcinoma. , 2017, Histology and histopathology.
[7] G. Mills,et al. Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer. , 2017, Cancer research.
[8] G. Iezzi,et al. MAGE-A Antigens and Cancer Immunotherapy , 2017, Front. Med..
[9] M. Sang,et al. MAGE-A family expression is correlated with poor survival of patients with lung adenocarcinoma: a retrospective clinical study based on tissue microarray , 2016, Journal of Clinical Pathology.
[10] B. Dai,et al. Extracellular lumican augments cytotoxicity of chemotherapy in pancreatic ductal adenocarcinoma cells via autophagy inhibition , 2016, Oncogene.
[11] Itay Mayrose,et al. ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules , 2016, Nucleic Acids Res..
[12] E. Cota,et al. Consequences of point mutations in melanoma-associated antigen 4 (MAGE-A4) protein: Insights from structural and biophysical studies , 2016, Scientific Reports.
[13] A. Brunet,et al. AMPK: An Energy-Sensing Pathway with Multiple Inputs and Outputs. , 2016, Trends in cell biology.
[14] Jennifer B Dennison,et al. Functional annotation of rare gene aberration drivers of pancreatic cancer , 2016, Nature Communications.
[15] Liqin Xu,et al. High expression levels of MAGE-A9 are correlated with unfavorable survival in lung adenocarcinoma , 2015, Oncotarget.
[16] Prasenjit Dey,et al. Genetics and biology of pancreatic ductal adenocarcinoma , 2006, Genes & development.
[17] C. Geng,et al. MAGE-A is frequently expressed in triple negative breast cancer and associated with epithelial-mesenchymal transition. , 2016, Neoplasma.
[18] J. Weon,et al. The MAGE protein family and cancer. , 2015, Current opinion in cell biology.
[19] P. Panda,et al. Mechanism of autophagic regulation in carcinogenesis and cancer therapeutics. , 2015, Seminars in cell & developmental biology.
[20] M. White,et al. Degradation of AMPK by a Cancer-Specific Ubiquitin Ligase , 2015, Cell.
[21] Jian Feng,et al. High expression of MAGE-A9 in tumor and stromal cells of non-small cell lung cancer was correlated with patient poor survival. , 2015, International journal of clinical and experimental pathology.
[22] Jin Zhu,et al. Overexpression of MAGE-A9 predicts unfavorable outcome in breast cancer. , 2014, Experimental and molecular pathology.
[23] D. Sabatini,et al. Regulation of mTORC1 by amino acids. , 2014, Trends in cell biology.
[24] Gerald C. Chu,et al. Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations. , 2014, Cancer discovery.
[25] P. Sykacek,et al. A dual role for autophagy in a murine model of lung cancer , 2014, Nature Communications.
[26] Jan Budczies,et al. Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer , 2013, PloS one.
[27] Amy Y. M. Au,et al. p53 status determines the role of autophagy in pancreatic tumour development , 2013, Nature.
[28] T. Treasure,et al. Adjuvant MAGE-A3 immunotherapy in resected non-small-cell lung cancer: phase II randomized study results. , 2013, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[29] T. Jacks,et al. Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis. , 2013, Genes & development.
[30] Lincoln D. Stein,et al. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes , 2012, Nature.
[31] Roberto Zoncu,et al. Amino acids and mTORC1: from lysosomes to disease. , 2012, Trends in molecular medicine.
[32] E. White. Deconvoluting the context-dependent role for autophagy in cancer , 2012, Nature Reviews Cancer.
[33] D. Bar-Sagi,et al. RAS oncogenes: weaving a tumorigenic web , 2011, Nature Reviews Cancer.
[34] A. Kimmelman,et al. The dynamic nature of autophagy in cancer. , 2011, Genes & development.
[35] C. Cole,et al. COSMIC: the catalogue of somatic mutations in cancer , 2011, Genome Biology.
[36] R. Shaw,et al. The AMPK signalling pathway coordinates cell growth, autophagy and metabolism , 2011, Nature Cell Biology.
[37] H. Coller,et al. Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. , 2011, Genes & development.
[38] Jianjun Wang,et al. Inhibition of autophagy by 3-MA potentiates cisplatin-induced apoptosis in esophageal squamous cell carcinoma cells , 2011, Medical oncology.
[39] C. Kenific,et al. Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation , 2011, Molecular biology of the cell.
[40] D. Sabatini,et al. mTOR: from growth signal integration to cancer, diabetes and ageing , 2010, Nature Reviews Molecular Cell Biology.
[41] Maojun Yang,et al. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. , 2010, Molecular cell.
[42] Lloyd J. Old,et al. Frequent MAGE Mutations in Human Melanoma , 2010, PloS one.
[43] D. Klionsky,et al. Eaten alive: a history of macroautophagy , 2010, Nature Cell Biology.
[44] A. Harris,et al. The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib. , 2009, Cancer research.
[45] H. Kuwano,et al. Inhibition of Autophagy by 3-MA Enhances the Effect of 5-FU-Induced Apoptosis in Colon Cancer Cells , 2009, Annals of Surgical Oncology.
[46] Oliver Hofmann,et al. Genome-wide analysis of cancer/testis gene expression , 2008, Proceedings of the National Academy of Sciences.
[47] Wei Liu,et al. The melanoma-associated antigen A3 mediates fibronectin-controlled cancer progression and metastasis. , 2008, Cancer research.
[48] E. Tartour,et al. Functions of Anti-MAGE T-cells induced in melanoma patients under different vaccination modalities. , 2008, Cancer research.
[49] Dan Garza,et al. HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS , 2007, Nature.
[50] Terje Johansen,et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death , 2005, The Journal of cell biology.
[51] Lloyd J. Old,et al. Cancer/testis antigens, gametogenesis and cancer , 2005, Nature Reviews Cancer.
[52] P. Barker,et al. The MAGE proteins: Emerging roles in cell cycle progression, apoptosis, and neurogenetic disease , 2002, Journal of neuroscience research.
[53] J. Sebolt-Leopold. Development of anticancer drugs targeting the MAP kinase pathway , 2000, Oncogene.
[54] D. Shibata,et al. Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes , 1988, Cell.