Regional and subcellular distribution of cytochrome P-450-dependent drug metabolism in monkey brain: the olfactory bulb and the mitochondrial fraction have high levels of activity.

[1]  M. Ingelman-Sundberg,et al.  Regional distribution of ethanol-inducible cytochrome P450 IIE1 in the rat central nervous system , 1990, Neuroscience.

[2]  M. Maines,et al.  Manganese-mediated increase in the rat brain mitochondrial cytochrome P-450 and drug metabolism activity: susceptibility of the striatum. , 1989, The Journal of pharmacology and experimental therapeutics.

[3]  M. Maines,et al.  Selective vulnerability of glutathione metabolism and cellular defense mechanisms in rat striatum to manganese. , 1988, The Journal of pharmacology and experimental therapeutics.

[4]  J. Gustafsson,et al.  Regional Distribution of Cytochrome P‐450 in the Rat Brain: Spectral Quantitation and Contribution of P‐450b,e and P‐450c,d , 1988, Journal of neurochemistry.

[5]  M. Waterman,et al.  Neurosteroids: cytochrome P-450scc in rat brain. , 1987, Science.

[6]  G. Siest,et al.  Brain mitochondrial cytochrome P-450scc: spectral and catalytic properties. , 1987, Archives of biochemistry and biophysics.

[7]  G. Siest,et al.  Ethoxyresorufin O-deethylase activity in rat brain subcellular fractions , 1987, Neuroscience Letters.

[8]  D. Jacobowitz,et al.  Immunohistochemical localization of cytochrome P-450 in rat brain , 1987, Neuroscience.

[9]  G. Siest,et al.  Subcellular distribution of cytochrome P-450 in the brain , 1986, Brain Research.

[10]  M. Maines,et al.  Regulation of heme and drug metabolism activities in the brain by manganese. , 1985, Biochemical and biophysical research communications.

[11]  J. W. Cameron,et al.  Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome(s) P-450 by phenobarbital and other xenobiotics in the rat. , 1985, Archives of biochemistry and biophysics.

[12]  C. Roselli,et al.  Regulation of brain aromatase activity in rats. , 1984, Endocrinology.

[13]  H. Mukhtar,et al.  Aryl hydrocarbon hydroxylase of rat brain mitochondria: properties of, and effect of inhibitors and inducers on, enzyme activity. , 1982, Archives of biochemistry and biophysics.

[14]  M. Maines Regional distribution of the enzymes of haem biosynthesis and the inhibition of 5-aminolaevulinate synthase by manganese in the rat brain. , 1980, The Biochemical journal.

[15]  J. DiGiovanni,et al.  A comparison of the capacity of fetal and adult liver, lung, and brain to convert polycyclic aromatic hydrocarbons to mutagenic and cytotoxic metabolites in mice and rats. , 1979, Toxicology and applied pharmacology.

[16]  S. Paul,et al.  Catechol estrogen-forming enzyme of brain: demonstration of a cytochrome p450 monooxygenase. , 1977, Endocrinology.

[17]  M. Ames,et al.  Cytochrome P-450 and NADPH cytochrome c reductase in rat brain: formation of catechols and reactive catechol metabolites. , 1977, Biochemical and biophysical research communications.

[18]  R. Mayer,et al.  Characteristics of a microsomal cytochrome P-448-mediated reaction. Ethoxyresorufin O-de-ethylation. , 1977, Drug metabolism and disposition: the biological fate of chemicals.

[19]  W. Dehnen,et al.  A modified method for the assay of benzo(a)pyrene hydroxylase. , 1973, Analytical biochemistry.

[20]  O. H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.