Anti-Inflammatory, Anti-Diabetic, and Anti-Alzheimer’s Effects of Prenylated Flavonoids from Okinawa Propolis: An Investigation by Experimental and Computational Studies
暂无分享,去创建一个
M. Hossain | T. Ishii | M. Halim | S. Tawata | M. Shahinozzaman | N. Taira
[1] M. Hossain,et al. Cytotoxic Desulfated Saponin from Holothuria atra Predicted to Have High Binding Affinity to the Oncogenic Kinase PAK1: A Combined In Vitro and In Silico Study. , 2018, Scientia pharmaceutica.
[2] F. Azam,et al. NSAIDs as potential treatment option for preventing amyloid β toxicity in Alzheimer’s disease: an investigation by docking, molecular dynamics, and DFT studies , 2018, Journal of biomolecular structure & dynamics.
[3] M. Kamal,et al. Flavonoids as acetylcholinesterase inhibitors: Current therapeutic standing and future prospects. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[4] S. Shah,et al. Synthesis, α-glucosidase inhibition and molecular docking study of coumarin based derivatives. , 2018, Bioorganic chemistry.
[5] M. Halim,et al. Multiple receptor conformers based molecular docking study of fluorine enhanced ethionamide with mycobacterium enoyl ACP reductase (InhA). , 2017, Journal of molecular graphics & modelling.
[6] J. Anireddy,et al. Synthesis and α-glucosidase inhibition activity of dihydroxy pyrrolidines. , 2017, Bioorganic & medicinal chemistry letters.
[7] S. Kumazawa,et al. Frondoside A from sea cucumber and nymphaeols from Okinawa propolis: Natural anti-cancer agents that selectively inhibit PAK1 in vitro. , 2017, Drug discoveries & therapeutics.
[8] Y. Uto,et al. 1,2,3-Triazolyl ester of Ketorolac: A "Click Chemistry"-based highly potent PAK1-blocking cancer-killer. , 2017, European journal of medicinal chemistry.
[9] A. Awal,et al. In vitro xanthine oxidase and albumin denaturation inhibition assay of Barringtonia racemosa L. and total phenolic content analysis for potential anti-infl ammatory use in gouty arthritis , 2016 .
[10] S. Chander,et al. Rational design, synthesis, anti-HIV-1 RT and antimicrobial activity of novel 3-(6-methoxy-3,4-dihydroquinolin-1(2H)-yl)-1-(piperazin-1-yl)propan-1-one derivatives. , 2016, Bioorganic chemistry.
[11] Md. Asiful Islam,et al. Type 2 Diabetes Mellitus and Alzheimer's Disease: Bridging the Pathophysiology and Management. , 2016, Current pharmaceutical design.
[12] D. Holtzman,et al. Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence? , 2016, The Journal of experimental medicine.
[13] S. Tawata,et al. Effect of Okinawa Propolis on PAK1 Activity, Caenorhabditis elegans Longevity, Melanogenesis, and Growth of Cancer Cells. , 2016, Journal of agricultural and food chemistry.
[14] D. Centeno,et al. Evaluation of acetylcholinesterase inhibitory activity of Brazilian red macroalgae organic extracts , 2015 .
[15] F. Azam,et al. Molecular interaction studies of green tea catechins as multitarget drug candidates for the treatment of Parkinson’s disease: computational and structural insights , 2015, Network.
[16] L. Misery,et al. Antioxidant and anti-inflammatory effects of Ruta chalepensis L. extracts on LPS-stimulated RAW 264.7 cells , 2015, In Vitro Cellular & Developmental Biology - Animal.
[17] A. Rauf,et al. Cytotoxic, antitumour-promoting and inhibition of protein denaturation effects of flavonoids, isolated from Potentilla evestita Th. Wolf , 2015, Natural product research.
[18] F. Azam,et al. Ginger components as new leads for the design and development of novel multi-targeted anti-Alzheimer’s drugs: a computational investigation , 2014, Drug design, development and therapy.
[19] H. Maruta. Herbal Therapeutics that Block the Oncogenic Kinase PAK1: A Practical Approach towards PAK1‐dependent Diseases and Longevity , 2014, Phytotherapy research : PTR.
[20] Andre Pascal Kengne,et al. Diabetes Mellitus and Inflammation , 2013, Current Diabetes Reports.
[21] Jie Shen,et al. admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties , 2012, J. Chem. Inf. Model..
[22] R. Curi,et al. Molecular Targets Related to Inflammation and Insulin Resistance and Potential Interventions , 2012, Journal of biomedicine & biotechnology.
[23] P. Salehi,et al. In vitro α-glucosidase inhibitory activity of phenolic constituents from aerial parts of Polygonum hyrcanicum , 2012, DARU Journal of Pharmaceutical Sciences.
[24] B. Aggarwal,et al. Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy. , 2012, Antioxidants & redox signaling.
[25] H. Hanyu,et al. Efficacy of PPAR-γ agonist pioglitazone in mild Alzheimer disease , 2011, Neurobiology of Aging.
[26] Said Bellahcen,et al. Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors. , 2010, Current diabetes reviews.
[27] J. van Staden,et al. Anti-inflammatory, anticholinesterase, antioxidant and phytochemical properties of medicinal plants used for pain-related ailments in South Africa. , 2010, Journal of ethnopharmacology.
[28] Zina Kroner,et al. The relationship between Alzheimer's disease and diabetes: Type 3 diabetes? , 2009, Alternative medicine review : a journal of clinical therapeutic.
[29] Arthur J. Olson,et al. AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading , 2009, J. Comput. Chem..
[30] Shabana I. Khan,et al. Cyclooxygenase‐2 inhibitory and antioxidant compounds from the truffle Elaphomyces granulatus , 2009, Phytotherapy research : PTR.
[31] R. Medzhitov. Origin and physiological roles of inflammation , 2008, Nature.
[32] K. Bae,et al. Anti-inflammatory activity of 4-methoxyhonokiol is a function of the inhibition of iNOS and COX-2 expression in RAW 264.7 macrophages via NF-kappaB, JNK and p38 MAPK inactivation. , 2008, European journal of pharmacology.
[33] A. Roses. Commentary on “A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium.” An impending prevention clinical trial for Alzheimer's disease: Roadmaps and realities , 2008, Alzheimer's & Dementia.
[34] E. Siemers,et al. Commentary on “A roadmap for the prevention of dementia: The inaugural Leon Thal Symposium” , 2008, Alzheimer's & Dementia.
[35] P. Mehta,et al. Intranasal insulin improves cognition and modulates β-amyloid in early AD , 2008, Neurology.
[36] Tsutomu Nakayama,et al. Antioxidant prenylated flavonoids from propolis collected in Okinawa, Japan. , 2007, Journal of agricultural and food chemistry.
[37] A. Goldfine,et al. Inflammation and insulin resistance. , 2006, The Journal of clinical investigation.
[38] Christina A. Wilson,et al. GSK-3α regulates production of Alzheimer's disease amyloid-β peptides , 2003, Nature.
[39] Anne Hersey,et al. Rate-Limited Steps of Human Oral Absorption and QSAR Studies , 2002, Pharmaceutical Research.
[40] G. Folkers,et al. Applications of density functional theory-based methods in medicinal chemistry , 2002 .
[41] P. Greengard,et al. Does insulin dysfunction play a role in Alzheimer's disease? , 2002, Trends in pharmacological sciences.
[42] Stephen R. Johnson,et al. Molecular properties that influence the oral bioavailability of drug candidates. , 2002, Journal of medicinal chemistry.
[43] Y. Song,et al. Caffeic acid phenethyl ester inhibits nitric oxide synthase gene expression and enzyme activity. , 2002, Cancer letters.
[44] C. Plata-salamán,et al. Inflammation and Alzheimer’s disease , 2000, Neurobiology of Aging.
[45] F. Lombardo,et al. Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings , 1997 .
[46] R. Li,et al. Use of dipole moment as a parameter in drug-receptor interaction and quantitative structure-activity relationship studies. , 1982, Journal of pharmaceutical sciences.
[47] K. Courtney,et al. A new and rapid colorimetric determination of acetylcholinesterase activity. , 1961, Biochemical pharmacology.
[48] N. Momose,et al. Analysis of antioxidant prenylflavonoids in different parts of Macaranga tanarius, the plant origin of Okinawan propolis. , 2014, Asian Pacific journal of tropical medicine.
[49] P. Moreira. Alzheimer's disease and diabetes: an integrative view of the role of mitochondria, oxidative stress, and insulin. , 2012, Journal of Alzheimer's disease : JAD.
[50] M. Reger,et al. Intranasal insulin improves cognition and modulates beta-amyloid in early AD. , 2008, Neurology.
[51] Christina A. Wilson,et al. GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides. , 2003, Nature.