The glycolytic oscillator.

The glycolytic oscillator, mainly studied in yeast, is described with respect to its overall dynamic and biochemical properties and the kinetics of its master enzyme phosphofructokinase. Biochemical and kinetic analyses are complemented by analysis of mathematical models. In addition to the discussion of structure and function of the glycolytic oscillator under homogeneous spatial conditions, recent theoretical and biochemical experiments demonstrating spatial pattern formation are also discussed, followed by a presentation of physiological viewpoints.

[1]  B Hess,et al.  Cooperation of glycolytic enzymes. , 1969, Advances in enzyme regulation.

[2]  P. Henderson,et al.  Biological and Biochemical Oscillators , 1974 .

[3]  B. Hess,et al.  Oscillatory phenomena in biochemistry. , 1971, Annual review of biochemistry.

[4]  B. Hess,et al.  VISUALIZATION OF DYNAMIC SPATIAL STRUCTURES IN OSCILLATING CELL FREE EXTRACTS OF YEAST , 1978 .

[5]  E. Stellwagen,et al.  Purification and properties of phosphofructokinase from yeast. , 1968, The Journal of biological chemistry.

[6]  A Goldbeter,et al.  Patterns of spatiotemporal organization in an allosteric enzyme model. , 1973, Proceedings of the National Academy of Sciences of the United States of America.

[7]  A Goldbeter,et al.  Oscillatory enzymes. , 1976, Annual review of biophysics and bioengineering.

[8]  B Hess,et al.  TEMPORAL AND SPATIAL ORDER IN BIOCHEMICAL SYSTEMS , 1979, Annals of the New York Academy of Sciences.

[9]  E. Sel'kov,et al.  Self-oscillations in glycolysis. 1. A simple kinetic model. , 1968, European journal of biochemistry.

[10]  B. Hess,et al.  Cyclic-AMP-controlled oscillations in suspended Dictyostelium cells: their relation to morphogenetic cell interactions. , 1974, Proceedings of the National Academy of Sciences of the United States of America.

[11]  A. Goldbeter,et al.  Control of oscillating glycolysis of yeast by stochastic, periodic, and steady source of substrate: a model and experimental study. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[12]  B. Hess,et al.  Purification and properties of phosphofructokinase (EC 2.7.1.11) of Saccharomyces carlsbergensis. , 1975, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[13]  B. Hess,et al.  Oscillations in glycolysis, cellular respiration and communication , 1974 .

[14]  V. V. Dynnik,et al.  On the possibility of self‐oscillations in the lower part of the glycolytic system , 1973 .

[15]  Hans-Georg Schweiger,et al.  The molecular basis of circadian rhythms : report of the Dahlem Workshop on the Molecular Basis of Circadian Rhythms, Berlin 1975, November 3 to 7 , 1976 .

[16]  Dieter Erle,et al.  The existence of stable limit cycles for enzyme catalyzed reactions with positive feedback , 1979 .

[17]  B. Schoener,et al.  CONTROLOF THE WAVEFORM OFOSCILLATIONS OF THE REDUCED PYRIDINENUCLEOTIDELEVEL IN A CELL-FREEEXTRACT , 1964 .

[18]  B. Hess Energy utilization for control. , 1975, Ciba Foundation symposium.

[19]  Britton Chance,et al.  Biological and biochemical oscillators , 1973 .