Semantic Visualization of Patient Information

Clinical practice and research rely increasingly on analytic approaches to patient data. Visualization enables the comparative exploration of similar patients, a key requirement in certain clinical decision support systems. Patient data is complex and heterogeneous, may have different formats, reside in various structures and carry different semantics. This makes the comparison and analysis of clinical data a challenging task. Most medical applications visualize patient data without integrating additional semantic information to structure the analysis. Our objective is to map patient data onto relevant fragments of ontologies and inferred ontological structures as a basis for improved patient data visualization, comparison, and analysis. Two visualization scenarios that we have implemented using the patient data acquired in the Health-e-Child project will be presented and their clinical evaluation will be provided.

[1]  Emmanuel Pietriga IsaViz, a Visual Environment for Browsing and Authoring RDF Models , 2002, WWW 2002.

[2]  Daniel A. Keim,et al.  Information Visualization and Visual Data Mining , 2002, IEEE Trans. Vis. Comput. Graph..

[3]  Daniel L. Rubin,et al.  Translating the Foundational Model of Anatomy into OWL , 2008, J. Web Semant..

[4]  Olivier Bodenreider,et al.  Migrating the FMA from Protégé to OWL , 2005 .

[5]  Alessio Bosca,et al.  OntoSphere: more than a 3D ontology visualization tool , 2005, SWAP.

[6]  Ben Shneiderman,et al.  Tree visualization with tree-maps: 2-d space-filling approach , 1992, TOGS.

[7]  Akrivi Katifori,et al.  Ontology visualization methods—a survey , 2007, CSUR.

[8]  Alexey Tsymbal,et al.  Visualizing Patient Similarity in Clinical Decision Support , 2007, LWA.

[9]  Daniel L. Rubin,et al.  Use of Description Logic Classification to Reason about Consequences of Penetrating Injuries , 2005, AMIA.

[10]  José L. V. Mejino,et al.  A reference ontology for biomedical informatics: the Foundational Model of Anatomy , 2003, J. Biomed. Informatics.

[11]  Hans Jürgen Ohlbach,et al.  Ontology Driven Visualisation of Maps with SVG - An Example for Semantic Programming , 2006, Tenth International Conference on Information Visualisation (IV'06).

[12]  Rafael Berlanga Llavori,et al.  OntoPath: A Language for Retrieving Ontology Fragments , 2007, OTM Conferences.

[13]  Amit P. Sheth,et al.  Semantic Visualization: Interfaces for Exploring and Exploiting Ontology, Knowledgebase, Heterogeneous Content and Complex Relationships , 2004 .

[14]  Trevor Paterson,et al.  Ontology-Driven Automated Generation of Data Entry Interfaces to Databases , 2004, BNCOD.

[15]  Peter Mika Ontologies Are Us: A Unified Model of Social Networks and Semantics , 2005, International Semantic Web Conference.

[16]  Paul S. Wang,et al.  An On-line MathML Editing Tool for Web Applications , 2007 .

[17]  Patrick Brézillon,et al.  Lecture Notes in Artificial Intelligence , 1999 .

[18]  Frank van Harmelen,et al.  Ontology-based information visualisation , 2001, Proceedings Fifth International Conference on Information Visualisation.

[19]  Vassilis Christophides,et al.  Onthology-Driven Integration of Scientific Repositories , 1999, NGITS.

[20]  Enrico Motta,et al.  A Knowledge-Based News Server Supporting Ontology-Driven Story Enrichment and Knowledge Retrieval , 1999, EKAW.

[21]  Mark A. Musen,et al.  The Knowledge Model of Protégé-2000: Combining Interoperability and Flexibility , 2000, EKAW.

[22]  Vasant Honavar,et al.  Information extraction and integration from heterogeneous, distributed, autonomous information sources - a federated ontology-driven query-centric approach , 2003, Proceedings Fifth IEEE Workshop on Mobile Computing Systems and Applications.

[23]  Mark T. Maybury,et al.  Semantic Visualization , 1998, Workshop On Content Visualization And Intermedia Representations.

[24]  D. Louis WHO classification of tumours of the central nervous system , 2007 .

[25]  Olivier Dameron,et al.  Grading lung tumors using OWL-DL based reasoning , 2006 .

[26]  Yuval Shahar,et al.  Ontology-Driven Visualization of Temporal Abstractions , 1998 .

[27]  Junyu Niu,et al.  Unified Mapping of Social Networks into 3D Space , 2007, Second International Multi-Symposiums on Computer and Computational Sciences (IMSCCS 2007).

[28]  B. Scheithauer,et al.  The 2007 WHO classification of tumours of the central nervous system , 2007, Acta Neuropathologica.

[29]  Vasant Honavar,et al.  Ontology-Driven Induction of Decision Trees at Multiple Levels of Abstraction , 2002, SARA.

[30]  Ian Horrocks,et al.  Just the right amount: extracting modules from ontologies , 2007, WWW '07.

[31]  Jennifer Golbeck,et al.  Visualization of semantic metadata and ontologies , 2003, Proceedings on Seventh International Conference on Information Visualization, 2003. IV 2003..