Genome-Wide Association Study of Temperament in Bipolar Disorder Reveals Significant Associations with Three Novel Loci

[1]  Naomi R. Wray,et al.  A genome-wide association study of Cloninger's temperament scales: Implications for the evolutionary genetics of personality , 2010, Biological Psychology.

[2]  Michael R. Johnson,et al.  A Genome-Wide Association Study of Neuroticism in a Population-Based Sample , 2010, PloS one.

[3]  G. Abecasis,et al.  Genome-wide association scan for five major dimensions of personality , 2010, Molecular Psychiatry.

[4]  H. Akiskal,et al.  Six-Year Stability of Affective Temperaments as Measured by TEMPS-A , 2010, Psychopathology.

[5]  John P. Rice,et al.  Genome-wide association study of bipolar disorder in European American and African American individuals , 2009, Molecular Psychiatry.

[6]  J. Savitz,et al.  Personality endophenotypes for bipolar affective disorder: a family‐based genetic association analysis , 2008, Genes, brain, and behavior.

[7]  Hans-Jürgen Möller,et al.  Genomewide association analysis followed by a replication study implicates a novel candidate gene for neuroticism. , 2008, Archives of general psychiatry.

[8]  Manuel A. R. Ferreira,et al.  Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder , 2008, Nature Genetics.

[9]  Manuel A. R. Ferreira,et al.  PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.

[10]  H. Akiskal,et al.  Validation of the TEMPS-A Buenos Aires: Spanish psychometric validation of affective temperaments in a population study of Argentina. , 2007, Journal of affective disorders.

[11]  Mohamed-Ali Hakimi,et al.  Integrator, a Multiprotein Mediator of Small Nuclear RNA Processing, Associates with the C-Terminal Repeat of RNA Polymerase II , 2005, Cell.

[12]  Murat Gunel,et al.  Sequence Variants in SLITRK1 Are Associated with Tourette's Syndrome , 2005, Science.

[13]  J. Kelsoe,et al.  Familiality of temperament in bipolar disorder: support for a genetic spectrum. , 2005, Journal of affective disorders.

[14]  H. Akiskal,et al.  Reliability and validity of TEMPS-A in a Japanese non-clinical population: application to unipolar and bipolar depressives. , 2005, Journal of affective disorders.

[15]  H. Akiskal,et al.  Studies on a German (Münster) version of the temperament auto-questionnaire TEMPS-A: construction and validation of the briefTEMPS-M. , 2005, Journal of affective disorders.

[16]  H. Akiskal,et al.  TEMPS-A: progress towards validation of a self-rated clinical version of the Temperament Evaluation of the Memphis, Pisa, Paris, and San Diego Autoquestionnaire. , 2005, Journal of affective disorders.

[17]  H. Akiskal,et al.  The cyclothymic temperament in healthy controls and familially at risk individuals for mood disorder: endophenotype for genetic studies? , 2005, Journal of affective disorders.

[18]  H. Akiskal,et al.  Affective temperaments as measured by TEMPS-A in patients with bipolar I disorder and their first-degree relatives: a controlled study. , 2005, Journal of affective disorders.

[19]  A. Marneros,et al.  Factorial structure and internal consistency of the German TEMPS-A scale: validation against the NEO-FFI questionnaire. , 2005, Journal of affective disorders.

[20]  J. Kelsoe,et al.  TEMPS-A: validation of a short version of a self-rated instrument designed to measure variations in temperament. , 2005, Journal of affective disorders.

[21]  J. Kelsoe,et al.  A comparison of recovered bipolar patients, healthy relatives of bipolar probands, and normal controls using the short TEMPS-A. , 2004, Journal of affective disorders.

[22]  A. Gurney,et al.  The netrin-G1 ligand NGL-1 promotes the outgrowth of thalamocortical axons , 2003, Nature Neuroscience.

[23]  Francis J McMahon,et al.  Suggestive linkage to chromosomal regions 13q31 and 22q12 in families with psychotic bipolar disorder. , 2003, The American journal of psychiatry.

[24]  H. Akiskal The bipolar spectrum—the shaping of a new paradigm in psychiatry , 2002, Current psychiatry reports.

[25]  S. Kohsaka,et al.  Fibulin‐1 binds the amino‐terminal head of β‐amyloid precursor protein and modulates its physiological function , 2001 .

[26]  M A Spence,et al.  A genome survey indicates a possible susceptibility locus for bipolar disorder on chromosome 22. , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[27]  H. Akiskal,et al.  A prospective study of stability and change over 2 years of affective temperaments in 14-18 year-old Italian high school students. , 1998, Journal of affective disorders.

[28]  H. Akiskal,et al.  TEMPS-I: delineating the most discriminant traits of the cyclothymic, depressive, hyperthymic and irritable temperaments in a nonpatient population. , 1998, Journal of affective disorders.

[29]  H. Akiskal,et al.  Systematic clinical methodology for validating bipolar-II disorder: data in mid-stream from a French national multi-site study (EPIDEP). , 1998, Journal of affective disorders.

[30]  G. Simpson Interpersonal factors in the origin and course of affective disorders: Christoph Mmndt, Michael J. Goldstein, Kurt Hahlweg and Peter Fiedler, with the assistance of Hugh Freeman: Royal College of Psychiatrists (1996) , 1997 .

[31]  M. Mattei,et al.  Human fibulin-1D: molecular cloning, expression and similarity with S1-5 protein, a new member of the fibulin gene family. , 1997, Matrix biology : journal of the International Society for Matrix Biology.

[32]  J. Nurnberger,et al.  Diagnostic interview for genetic studies. Rationale, unique features, and training. NIMH Genetics Initiative. , 1994, Archives of general psychiatry.

[33]  C. Gatsonis,et al.  Childhood-onset dysthymic disorder. Clinical features and prospective naturalistic outcome. , 1994, Archives of general psychiatry.

[34]  H. Akiskal Delineating Irritable and Hyperthymic Variants Of the Cyclothymic Temperament , 1992 .

[35]  H. Akiskal,et al.  Proposed subtypes of bipolar II and related disorders: with hypomanic episodes (or cyclothymia) and with hyperthymic temperament. , 1992, Journal of affective disorders.

[36]  M. Weissman,et al.  Depressive symptoms as relative and attributable risk factors for first-onset major depression. , 1992, Archives of general psychiatry.

[37]  M. Somerman,et al.  Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure , 1990, The Journal of cell biology.

[38]  R. Hinde,et al.  Roundtable: what is temperament? Four approaches. , 1987, Child development.

[39]  H. Akiskal,et al.  Affective disorders in referred children and younger siblings of manic-depressives. Mode of onset and prospective course. , 1985, Archives of general psychiatry.

[40]  L. Tondo,et al.  Rapid cyclers, temperament, and antidepressants. , 1983, Comprehensive psychiatry.

[41]  J. Nurnberger,et al.  A family study of schizoaffective, bipolar I, bipolar II, unipolar, and normal control probands. , 1982, Archives of general psychiatry.

[42]  H. Akiskal,et al.  Cyclothymic disorder: validating criteria for inclusion in the bipolar affective group. , 1977, The American journal of psychiatry.

[43]  H. Akiskal,et al.  The influence of affective temperaments and psychopathological traits on the definition of bipolar disorder subtypes: a study on bipolar I Italian national sample. , 2012, Journal of affective disorders.

[44]  H. Akiskal,et al.  Current research on affective temperaments. , 2010, Current opinion in psychiatry.

[45]  M C Neale,et al.  A whole genome association study of neuroticism using DNA pooling , 2008, Molecular Psychiatry.

[46]  J. Kelsoe Arguments for the genetic basis of the bipolar spectrum. , 2003, Journal of affective disorders.

[47]  J. Kelsoe,et al.  Linkage of a bipolar disorder susceptibility locus to human chromosome 13q32 in a new pedigree series , 2003, Molecular Psychiatry.

[48]  E. Gershon,et al.  Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia , 2002, Molecular Psychiatry.

[49]  H. Akiskal,et al.  The soft bipolar spectrum: footnotes to Kraepelin on the interface of hypomania, temperament and depression , 2000 .

[50]  A. Marneros,et al.  Bipolar disorders : 100 years after manic-depressive insanity , 2000 .

[51]  H. Akiskal,et al.  The semi-structured affective temperament interview (TEMPS-I). Reliability and psychometric properties in 1010 14-26-year old students. , 1998, Journal of affective disorders.

[52]  H. Akiskal Toward a temperament-based approach to depression: implications for neurobiologic research. , 1995, Advances in biochemical psychopharmacology.

[53]  H. Akiskal,et al.  Cyclothymic, hyperthymic, and depressive temperaments as subaffective variants of mood disorders. , 1992 .

[54]  H. Akiskal,et al.  Psychopathology, temperament, and past course in primary major depressions. 2. Toward a redefinition of bipolarity with a new semistructured interview for depression. , 1989, Psychopathology.

[55]  H. Akiskal,et al.  Psychopathology, temperament, and past course in primary major depressions. 1. Review of evidence for a bipolar spectrum. , 1989, Psychopathology.

[56]  K. Kidd,et al.  Multiple threshold models for the affective disorders: the Yale-NIMH collaborative family study. , 1985, Journal of psychiatric research.

[57]  R. Hales,et al.  Psychiatry update : American Psychiatric Association annual review , 1983 .