Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesothelioma.
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N. Reguart | L. You | D. Jablons | Yu-Ching Lin | I. Mikami | K. Kuchenbecker | B. He | Yihui Shi | Zhidong Xu | S. Batra | G. Clément | G. Clément | Biao He
[1] Cheng-Ta Yang,et al. Wnt signaling activation and WIF-1 silencing in nasopharyngeal cancer cell lines. , 2006, Biochemical and biophysical research communications.
[2] Hiroyuki Yamamoto,et al. Frequent epigenetic inactivation of Wnt inhibitory factor-1 in human gastrointestinal cancers , 2005, Oncogene.
[3] B. Ljung,et al. The gene expression signatures of melanoma progression , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[4] M. Koch,et al. The extracellular matrix component WIF-1 is expressed during, and can modulate, retinal development , 2004, Molecular and Cellular Neuroscience.
[5] Amie Y Lee,et al. Cloning and characterization of the promoter of human Wnt inhibitory factor-1. , 2004, Biochemical and biophysical research communications.
[6] J. Behrens,et al. The Wnt connection to tumorigenesis. , 2004, The International journal of developmental biology.
[7] Biao He,et al. Expression of the secreted frizzled-related protein gene family is downregulated in human mesothelioma , 2004, Oncogene.
[8] N. Thatcher. Second Heidelberg Thoracic Oncology Symposium on the Diagnosis and Treatment of Pleural Mesothelioma--introduction. , 2004, Lung cancer.
[9] Biao He,et al. Wnt Inhibitory Factor-1 Is Silenced by Promoter Hypermethylation in Human Lung Cancer , 2004, Cancer Research.
[10] Wei Dong Chen,et al. Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer , 2004, Nature Genetics.
[11] T. Kipps,et al. Activation of the Wnt signaling pathway in chronic lymphocytic leukemia. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[12] Yvonne Wallis,et al. The Wnt Antagonist sFRP1 in Colorectal Tumorigenesis , 2004, Cancer Research.
[13] Biao He,et al. Activation of the Wnt pathway in non small cell lung cancer: evidence of dishevelled overexpression , 2003, Oncogene.
[14] Christian Pilarsky,et al. WIF1, a component of the Wnt pathway, is down‐regulated in prostate, breast, lung, and bladder cancer , 2003, The Journal of pathology.
[15] Jeffrey D. Axelrod,et al. A Second Canon , 2003 .
[16] K. Uematsu,et al. Wnt pathway activation in mesothelioma: evidence of Dishevelled overexpression and transcriptional activity of beta-catenin. , 2003, Cancer research.
[17] Yoshiaki Kawano,et al. Secreted antagonists of the Wnt signalling pathway , 2003, Journal of Cell Science.
[18] J. Kim,et al. Human secreted frizzled-related protein is down-regulated and induces apoptosis in human cervical cancer. , 2002, Experimental cell research.
[19] Matthias Mann,et al. Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. , 2002, Genes & development.
[20] M. Bittner,et al. Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma. , 2002, Cancer cell.
[21] Xi He,et al. Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism , 2002, Cell.
[22] B. Boman,et al. Evidence that APC regulates survivin expression: a possible mechanism contributing to the stem cell origin of colon cancer. , 2001, Cancer research.
[23] F. Chan,et al. Alterations of frizzled (FzE3) and secreted frizzled related protein (hsFRP) expression in gastric cancer. , 2001, Life sciences.
[24] D. Birnbaum,et al. WNT pathway and mammary carcinogenesis: Loss of expression of candidate tumor suppressor gene SFRP1 in most invasive carcinomas except of the medullary type , 2001, Oncogene.
[25] D. Chung,et al. Regulation of vascular endothelial growth factor by the Wnt and K-ras pathways in colonic neoplasia. , 2001, Cancer research.
[26] P. Polakis. Wnt signaling and cancer. , 2000, Genes & development.
[27] R. Bueno. Mesothelioma clinical presentation. , 1999, Chest.
[28] A. Ishimoto,et al. Characterization of Mouse Dishevelled (Dvl) Proteins in Wnt/Wingless Signaling Pathway* , 1999, The Journal of Biological Chemistry.
[29] M. Kraus,et al. Isolation and Biochemical Characterization of the Human Dkk-1 Homologue, a Novel Inhibitor of Mammalian Wnt Signaling* , 1999, The Journal of Biological Chemistry.
[30] Akira Kikuchi,et al. DIX Domains of Dvl and Axin Are Necessary for Protein Interactions and Their Ability To Regulate β-Catenin Stability , 1999, Molecular and Cellular Biology.
[31] C. Albanese,et al. The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[32] M. Kitagawa,et al. An F‐box protein, FWD1, mediates ubiquitin‐dependent proteolysis of β‐catenin , 1999, The EMBO journal.
[33] J. Nathans,et al. A new secreted protein that binds to Wnt proteins and inhibits their activites , 1999, Nature.
[34] R. Benarous,et al. The F-box protein β-TrCP associates with phosphorylated β-catenin and regulates its activity in the cell , 1999, Current Biology.
[35] Stephen J. Elledge,et al. The SCFβ-TRCP–ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IκBα and β-catenin and stimulates IκBα ubiquitination in vitro , 1999 .
[36] S. Sokol,et al. Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and β-catenin , 1998, Current Biology.
[37] Akira Kikuchi,et al. Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin , 1998 .
[38] J. Herndon,et al. Factors predictive of survival among 337 patients with mesothelioma treated between 1984 and 1994 by the Cancer and Leukemia Group B. , 1998, Chest.
[39] F. Luyten,et al. The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[40] Hans Clevers,et al. Activation of β-Catenin-Tcf Signaling in Colon Cancer by Mutations in β-Catenin or APC , 1997, Science.
[41] Michael Kühl,et al. Functional interaction of β-catenin with the transcription factor LEF-1 , 1996, Nature.
[42] Paul Polakis,et al. Binding of GSK3β to the APC-β-Catenin Complex and Regulation of Complex Assembly , 1996, Science.
[43] C. Harris,et al. Asbestos-associated chromosomal changes in human mesothelial cells. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[44] S. Rosenberg,et al. Adoptive immunotherapy of newly induced murine sarcomas. , 1985, Cancer research.
[45] Harold E. Varmus,et al. Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome , 1982, Cell.
[46] K. Marumo,et al. Inhibition of Wnt signaling downregulates Akt activity and induces chemosensitivity in PTEN‐mutated prostate cancer cells , 2005, The Prostate.
[47] Amie Y Lee,et al. A monoclonal antibody against Wnt-1 induces apoptosis in human cancer cells. , 2004, Neoplasia.
[48] L. Patthy,et al. The WIF module. , 2000, Trends in biochemical sciences.