Monitoring Depth of Anesthesia with the EEG

“Is the EEG a measure for the depth of anesthesia?” can be translated as “Is there a uniform, recognizable EEG pattern correlated with graded levels of anesthesia?” and in extension “Is there a correlation between input (dose of the drug and plasmalevels) and output (ERG)?”. Presently, there can be little doubt that the EEG is the best, single, non-invasive and sensitive indicator of cerebral function. In anesthesia, the question then is: do the EEG changes reflect anesthetic depth and, how should one monitor the EEG?

[1]  L. Goldstein,et al.  Amplitude analysis of the electroencephalogram. Review of the information obtained with the integrative method. , 1965, International review of neurobiology.

[2]  D. A. Davis,et al.  The Use of the Time Domain Analyzed EEG in Conjunction with Cardiovascular Parameters for Monitoring Anesthetic Levels , 1981, IEEE Transactions on Biomedical Engineering.

[3]  Janssen Pa,et al.  The inhibitory effect of fentanyl and other morphine-like analgesics on the warm water induced tail withdrawl reflex in rats. , 1963 .

[4]  Donald R. Stanski,et al.  Pharmacodynamic modeling of thiopental anesthesia , 1984, Journal of Pharmacokinetics and Biopharmaceutics.

[5]  P. Sebel,et al.  Influence of high-dose alfentanil anaesthesia on the electroencephalogram: correlation with plasma concentrations. , 1983, British journal of anaesthesia.

[6]  Hughes Cc Lipid solubility, pharmacokinetics, and the EEG: are you better off today than you were four years ago? , 1985 .

[7]  N. T. Smith,et al.  SPECTRAL EDGE FREQUENCY — A NEW CORRELATE OF ANESTHETIC DEPTH , 1980 .

[8]  P. Prior EEG monitoring and evoked potentials in brain ischaemia. , 1985, British journal of anaesthesia.

[9]  H. Edmonds,et al.  Effects of flunarizine on recovery of cerebral function following cardiac arrest. , 1985, Neuropsychobiology.

[10]  A. Wauquier,et al.  Effects of morphine, fentanyl, sufentanil, and the short‐acting morphine‐like analgesic alfentanil on the EEG in dogs , 1981 .

[11]  P. Sebel,et al.  Effects of High‐dose Fentanyl Anesthesia on the Electroencephalogram , 1981, Anesthesiology.

[12]  D R Stanski,et al.  EEG quantitation of narcotic effect: the comparative pharmacodynamics of fentanyl and alfentanil. , 1985, Anesthesiology.

[13]  F H Lopes da Silva,et al.  Spectral analysis of the EEG during halothane anaesthesia: input-output relations. , 1972, Electroencephalography and clinical neurophysiology.

[14]  D R Stanski,et al.  A Model for Studying Depth of Anesthesia and Acute Tolerance to Thiopental , 1983, Anesthesiology.

[15]  P. Sebel,et al.  Electroencephalographic effects of sufentanil anaesthesia in man. , 1982, British journal of anaesthesia.

[16]  P. Sebel,et al.  Electroencephalographic effects of fentanyl-, sufentanil- and alfentanil anaesthesia in man. , 1984, Neuropsychobiology.

[17]  I. Rampil,et al.  Prognostic Value of Computerized EEG Analysis during Carotid Endarterectomy , 1983, Anesthesia and analgesia.