Kinetic Modeling without Accounting for the Vascular Component Impairs the Quantification of [11C]PBR28 Brain PET Data
暂无分享,去创建一个
Alessandra Bertoldo | Matteo Tonietto | Gaia Rizzo | Mattia Veronese | Federico E Turkheimer | Paolo Zanotti-Fregonara | F. Turkheimer | M. Veronese | A. Bertoldo | P. Zanotti-Fregonara | G. Rizzo | M. Tonietto | Matteo Tonietto
[1] M. Mintun,et al. A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography , 1984, Annals of neurology.
[2] Alessandra Bertoldo,et al. Use of Spectral Analysis with Iterative Filter for Voxelwise Determination of Regional Rates of Cerebral Protein Synthesis with L-[1-11C]leucine PET , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[3] W. Wong. Microglial aging in the healthy CNS: phenotypes, drivers, and rejuvenation , 2013, Front. Cell. Neurosci..
[4] J. Godbout,et al. Review: Microglia of the aged brain: primed to be activated and resistant to regulation , 2013, Neuropathology and applied neurobiology.
[5] J. Gatliff,et al. The 18 kDa translocator protein (TSPO): a new perspective in mitochondrial biology. , 2012, Current molecular medicine.
[6] J Delforge,et al. Concept of reaction volume in the in vivo ligand-receptor model. , 1996, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[7] Robert B. Innis,et al. Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation , 2008, NeuroImage.
[8] Sunhee C. Lee,et al. Expression of the translocator protein of 18 kDa by microglia, macrophages and astrocytes based on immunohistochemical localization in abnormal human brain , 2009, Neuropathology and applied neurobiology.
[9] Rolf A Heckemann,et al. The Predictive Power of Brain mRNA Mappings for in vivo Protein Density: A Positron Emission Tomography Correlation Study , 2014, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[10] Alessandra Bertoldo,et al. ORIGINAL ARTICLE Voxelwise quantification of ( 11 C)(R)-rolipram PET data: a comparison between model-based and data-driven methods , 2013 .
[11] R. Carson,et al. The neuroinflammation marker translocator protein is not elevated in individuals with mild-to-moderate depression: A [11C]PBR28 PET study , 2013, Brain, Behavior, and Immunity.
[12] Masahiro Fujita,et al. Kinetic analysis in human brain of [11C](R)-rolipram, a positron emission tomographic radioligand to image phosphodiesterase 4: A retest study and use of an image-derived input function , 2011, NeuroImage.
[13] Hervé Boutin,et al. Nuclear imaging of neuroinflammation: a comprehensive review of [11C]PK11195 challengers , 2008, European Journal of Nuclear Medicine and Molecular Imaging.
[14] Jeih-San Liow,et al. PET imaging of the dopamine transporter with 18F-FECNT: a polar radiometabolite confounds brain radioligand measurements. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[15] Peter Herscovitch,et al. Propofol Decreases In Vivo Binding of 11C-PBR28 to Translocator Protein (18 kDa) in the Human Brain , 2013, The Journal of Nuclear Medicine.
[16] J Versijpt,et al. PET visualization of microglia in multiple sclerosis patients using [11C]PK11195 , 2003, European journal of neurology.
[17] Jeih-San Liow,et al. Image-Derived Input Function for Human Brain Using High Resolution PET Imaging with [11C](R)-rolipram and [11C]PBR28 , 2011, PloS one.
[18] Alessandra Bertoldo,et al. Novel Reference Region Model Reveals Increased Microglial and Reduced Vascular Binding of 11C-(R)-PK11195 in Patients with Alzheimer's Disease , 2008, Journal of Nuclear Medicine.
[19] Kimberly J. Jenko,et al. A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation , 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[20] R B Banati,et al. [11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy , 2003, Neurology.
[21] Bertrand Tavitian,et al. Noninvasive molecular imaging of neuroinflammation , 2012, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[22] C. Cobelli,et al. Evaluation of compartmental and spectral analysis models of [/sup 18/F]FDG kinetics for heart and brain studies with PET , 1998, IEEE Transactions on Biomedical Engineering.
[23] Alan A. Wilson,et al. Neuroinflammation in healthy aging: A PET study using a novel Translocator Protein 18kDa (TSPO) radioligand, [18F]-FEPPA , 2014, NeuroImage.
[24] Federico E. Turkheimer,et al. Identifying improved TSPO PET imaging probes through biomathematics: The impact of multiple TSPO binding sites in vivo , 2012, NeuroImage.
[25] B. Bogerts,et al. Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia and depression is associated with suicide. , 2008, Journal of psychiatric research.
[26] Robert B. Innis,et al. Mixed-Affinity Binding in Humans with 18-kDa Translocator Protein Ligands , 2011, The Journal of Nuclear Medicine.
[27] Allan R. Jones,et al. An anatomically comprehensive atlas of the adult human brain transcriptome , 2012, Nature.
[28] Alexander Gerhard,et al. In vivo imaging of neuroinflammation , 2002, European Neuropsychopharmacology.
[29] C Cobelli,et al. Kinetic modeling of [(18)F]FDG in skeletal muscle by PET: a four-compartment five-rate-constant model. , 2001, American journal of physiology. Endocrinology and metabolism.
[30] F. Turkheimer,et al. Reference and target region modeling of [11C]-(R)-PK11195 brain studies. , 2007, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[31] Francis J McMahon,et al. In vivo radioligand binding to translocator protein correlates with severity of Alzheimer's disease. , 2013, Brain : a journal of neurology.