Gambogic Acid‐induced Autophagy and the MAPK Pathway in T98G Glioblastoma Cells

[1]  P. Delgado-López,et al.  Survival in glioblastoma: a review on the impact of treatment modalities , 2016, Clinical and Translational Oncology.

[2]  Inki Kim,et al.  Gambogic acid induces apoptotic cell death in T98G glioma cells. , 2016, Bioorganic & medicinal chemistry letters.

[3]  S. Amin,et al.  Gambogic Acid and Its Role in Chronic Diseases. , 2016, Advances in experimental medicine and biology.

[4]  Jun Sun,et al.  ROS-Mediated Autophagy Induced by Dysregulation of Lipid Metabolism Plays a Protective Role in Colorectal Cancer Cells Treated with Gambogic Acid , 2014, PloS one.

[5]  T. Cloughesy,et al.  Glioblastoma: from molecular pathology to targeted treatment. , 2014, Annual review of pathology.

[6]  K. Aldape,et al.  Using the molecular classification of glioblastoma to inform personalized treatment , 2014, The Journal of pathology.

[7]  B. Aggarwal,et al.  Gambogic Acid Inhibits STAT3 Phosphorylation through Activation of Protein Tyrosine Phosphatase SHP-1: Potential Role in Proliferation and Apoptosis , 2011, Cancer Prevention Research.

[8]  Di Chen,et al.  Gambogic acid enhances proteasome inhibitor-induced anticancer activity. , 2011, Cancer letters.

[9]  A. Kinghorn,et al.  Discovery of natural product anticancer agents from biodiverse organisms. , 2009, Current opinion in drug discovery & development.

[10]  J. Tao,et al.  Gambogic acid induces apoptosis by regulating the expression of Bax and Bcl‐2 and enhancing caspase‐3 activity in human malignant melanoma A375 cells , 2009, International journal of dermatology.

[11]  P. Hunter.  Harnessing Nature's wisdom , 2008, EMBO reports.

[12]  Yong Yang,et al.  Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in human breast carcinoma MCF-7 cells. , 2008, Life sciences.

[13]  Mingyao Liu,et al.  Gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling. , 2008, Cancer research.

[14]  A. Panthong,et al.  Anti-inflammatory, analgesic and antipyretic activities of the extract of gamboge from Garcinia hanburyi Hook f. , 2007, Journal of ethnopharmacology.

[15]  D. Newman,et al.  Natural products as sources of new drugs over the last 25 years. , 2007, Journal of natural products.

[16]  Li Zhao,et al.  Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823. , 2005, World journal of gastroenterology.

[17]  Q. You,et al.  Gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells. , 2004, Biological & pharmaceutical bulletin.

[18]  S. Kasibhatla,et al.  Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay. , 2004, Bioorganic & medicinal chemistry.

[19]  R. Donehower,et al.  Taxol: a novel investigational antimicrotubule agent. , 1990, Journal of the National Cancer Institute.

[20]  P. Schiff,et al.  Promotion of microtubule assembly in vitro by taxol , 1979, Nature.

[21]  A. McPhail,et al.  Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia. , 1971, Journal of the American Chemical Society.

[22]  A. McPhail,et al.  Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2 , 1966 .

[23]  R L NOBLE,et al.  ROLE OF CHANCE OBSERVATIONS IN CHEMOTHERAPY: VINCA ROSEA * , 1958, Annals of the New York Academy of Sciences.