Fine mapping of hepatitis B virus pre‐S deletion and its association with hepatocellular carcinoma

Naturally occurring pre‐S deletion mutants have been identified in hepatitis B virus (HBV)‐related hepatocellular carcinoma (HCC).

[1]  Chih-Ming Lin,et al.  Functional analysis of hepatitis B virus pre-s deletion variants associated with hepatocellular carcinoma , 2012, Journal of Biomedical Science.

[2]  M. Yuen,et al.  Association of hepatitis B virus pre-S deletions with the development of hepatocellular carcinoma in chronic hepatitis B. , 2011, The Journal of infectious diseases.

[3]  J. Kao,et al.  The clinical implications of hepatitis B virus genotype: Recent advances , 2011, Journal of gastroenterology and hepatology.

[4]  H. Hsu,et al.  Pre-S2 Deletions of Hepatitis B Virus and Hepatocellular Carcinoma in Children , 2010, Pediatric Research.

[5]  S. Thung,et al.  Pre‐S2 deletion mutants of hepatitis B virus could have an important role in hepatocarcinogenesis in Asian children , 2009, Cancer science.

[6]  H. Poustchi,et al.  The role of mutations in core protein of hepatitis B virus in liver fibrosis , 2009, Virology Journal.

[7]  I. Su,et al.  Enhanced expression of vascular endothelial growth factor‐A in ground glass hepatocytes and its implication in hepatitis B virus hepatocarcinogenesis , 2009, Hepatology.

[8]  C. Sabin,et al.  Hepatitis B virus pre-S deletion mutations are a risk factor for hepatocellular carcinoma: a matched nested case–control study , 2008, The Journal of general virology.

[9]  I. Su,et al.  Ground glass hepatocytes contain pre‐S mutants and represent preneoplastic lesions in chronic hepatitis B virus infection , 2008, Journal of gastroenterology and hepatology.

[10]  C. Sabin,et al.  Hepatitis B virus preS deletion mutations are a risk factor for hepatocellular carcinoma : a matched nested case – control study , 2008 .

[11]  Sheng-Nan Lu,et al.  Pre-S deletion and complex mutations of hepatitis B virus related to advanced liver disease in HBeAg-negative patients. , 2007, Gastroenterology.

[12]  Ding‐Shinn Chen,et al.  High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases. , 2006, Gastroenterology.

[13]  Ding‐Shinn Chen,et al.  Evolution of Hepatitis B virus in an acute hepatitis B patient co-infected with genotypes B and C. , 2006, The Journal of general virology.

[14]  M. Lai,et al.  Novel Autoregulatory Function of Hepatitis B Virus M Protein on Surface Gene Expression* , 2005, Journal of Biological Chemistry.

[15]  Christian Bréchot,et al.  Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms. , 2004, Gastroenterology.

[16]  Ding‐Shinn Chen,et al.  Quantification and genotyping of hepatitis B virus in a single reaction by real-time PCR and melting curve analysis. , 2004, Journal of hepatology.

[17]  M. Lai,et al.  Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damage. , 2004, Carcinogenesis.

[18]  Ding‐Shinn Chen,et al.  Genotypic dominance and novel recombinations in HBV genotype B and C co‐infected intravenous drug users , 2004, Journal of medical virology.

[19]  Chien-Fu Chen,et al.  Different types of ground glass hepatocytes in chronic hepatitis B virus infection contain specific pre-S mutants that may induce endoplasmic reticulum stress. , 2003, The American journal of pathology.

[20]  Ding‐Shinn Chen,et al.  Basal core promoter mutations of hepatitis B virus increase the risk of hepatocellular carcinoma in hepatitis B carriers. , 2003, Gastroenterology.

[21]  Ding-Shinn Chen,et al.  Global control of hepatitis B virus infection. , 2002, The Lancet. Infectious diseases.

[22]  M. Masetti,et al.  Pretransplantation pre‐S2 and S protein heterogeneity predisposes to hepatitis B virus recurrence after liver transplantation , 2002, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[23]  W. Gerlich,et al.  Hypermodification and immune escape of an internally deleted middle-envelope (M) protein of frequent and predominant hepatitis B virus variants. , 2002, Virology.

[24]  H. Lei,et al.  Prevalence and significance of hepatitis B virus (HBV) pre‐S mutants in serum and liver at different replicative stages of chronic HBV infection , 2001, Hepatology.

[25]  E. Cho,et al.  Determination of the Protective Effects of Neutralizing Anti‐Hepatitis B Virus (HBV) Immunoglobulins by Epitope Mapping with Recombinant HBV Surface‐Antigen Proteins , 2000, Microbiology and immunology.

[26]  C. Ryu,et al.  Fine mapping of virus-neutralizing epitopes on hepatitis B virus PreS1. , 2000, Virology.

[27]  F. Chisari,et al.  Rous-Whipple Award Lecture. Viruses, immunity, and cancer: lessons from hepatitis B. , 2000, The American journal of pathology.

[28]  C. Seeger,et al.  Hepatitis B Virus Biology , 2000, Microbiology and Molecular Biology Reviews.

[29]  P. Pumpens,et al.  Mapping of immunodominant B-cell epitopes and the human serum albumin-binding site in natural hepatitis B virus surface antigen of defined genosubtype. , 2000, The Journal of general virology.

[30]  M. Manns,et al.  Two control elements in the hepatitis B virus S‐promoter are important for full promoter activity mediated by CCAAT‐binding factor , 1999, Hepatology.

[31]  C. Guguen-Guillouzo,et al.  Role of the Pre-S2 Domain of the Large Envelope Protein in Hepatitis B Virus Assembly and Infectivity , 1998, Journal of Virology.

[32]  M. Manns,et al.  A preS mutation isolated from a patient with chronic hepatitis B infection leads to virus retention and misassembly. , 1997, Gastroenterology.

[33]  V. Bruss.  A short linear sequence in the pre-S domain of the large hepatitis B virus envelope protein required for virion formation , 1997, Journal of virology.

[34]  R. Prange,et al.  Sequence-specific repression of cotranslational translocation of the hepatitis B virus envelope proteins coincides with binding of heat shock protein Hsc70. , 1997, Virology.

[35]  J. Wands,et al.  The small envelope protein is required for secretion of a naturally occurring hepatitis B virus mutant with pre-S1 deleted , 1997, Journal of virology.

[36]  R. Dwek,et al.  Aberrant trafficking of hepatitis B virus glycoproteins in cells in which N-glycan processing is inhibited. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[37]  C. Hourioux,et al.  Both pre-S1 and S domains of hepatitis B virus envelope proteins interact with the core particle. , 1997, Virology.

[38]  P. Hofschneider,et al.  The hepatitis B virus large surface protein (LHBs) is a transcriptional activator. , 1996, Virology.

[39]  T. Yen,et al.  Intracellular retention of surface protein by a hepatitis B virus mutant that releases virion particles , 1996, Journal of virology.

[40]  P. Hofschneider,et al.  Characterization of essential domains for the functionality of the MHBst transcriptional activator and identification of a minimal MHBst activator. , 1995, Oncogene.

[41]  A. Bertoletti,et al.  Fine specificity of the human T-cell response to the hepatitis B virus preS1 antigen. , 1992, Gastroenterology.

[42]  D. Ganem,et al.  Epitope mapping of the PreS1 domain of the hepatitis B virus large surface protein. , 1990, Virology.

[43]  A. Moriarty,et al.  Importance of subtype in the immune response to the pre-S(2) region of the hepatitis B surface antigen. II. Synthetic Pre-S(2) immunogen. , 1990, Journal of immunology.

[44]  G. B. Thornton,et al.  Importance of subtype in the immune response to the pre-S(2) region of the hepatitis B surface antigen. I. T cell fine specificity. , 1990, Journal of immunology.

[45]  P. Pontisso,et al.  Identification of an attachment site for human liver plasma membranes on hepatitis B virus particles. , 1989, Virology.

[46]  A. R. Neurath,et al.  Identification and chemical synthesis of a host cell receptor binding site on hepatitis B virus , 1986, Cell.