A CMOS Σ-Δ photodetector array for bioluminescence-based DNA sequencing

A fully-integrated photodetector array for long-read length bioluminescence-based DNA sequence-by-synthesis is implemented. Each pixel has 120dB photocurrent detection dynamic range and includes a 10fA–10nA pulse frequency modulation (PFM) background subtraction block and a 1st-order Σ-Δ modulator.

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