Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

[1]  A. Roses,et al.  Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. , 1994, The Journal of clinical investigation.

[2]  T. Iwatsubo,et al.  Visualization of Aβ42(43) and Aβ40 in senile plaques with end-specific Aβ monoclonals: Evidence that an initially deposited species is Aβ42(43) , 1994, Neuron.

[3]  A. M. Saunders,et al.  Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease , 1994, Nature Genetics.

[4]  S. Younkin,et al.  An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. , 1994, Science.

[5]  M J Ball,et al.  beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[6]  A D Roses,et al.  Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[7]  B. Hyman,et al.  Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions , 1993, Neuron.

[8]  J. Haines,et al.  Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. , 1993, Science.

[9]  I. Lieberburg,et al.  Cells with a familial Alzheimer's disease mutation produce authentic beta-peptide. , 1993, Neuroreport.

[10]  P. Fraser,et al.  α1‐Antichymotrypsin Binding to Alzheimer Aβ Peptides Is Sequence Specific and Induces Fibril Disaggregation In Vitro , 1993 .

[11]  T. Wisniewski,et al.  Apolipoprotein E : binding to soluble Alzheimer's β-amyloid , 1993 .

[12]  M. Pericak-Vance,et al.  Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[13]  R. Nelson,et al.  The Involvement of Proteases, Protease Inhibitors, and an Acute Phase Response in Alzheimer's Disease a , 1992, Annals of the New York Academy of Sciences.

[14]  S. Estus,et al.  Production of the Alzheimer amyloid beta protein by normal proteolytic processing. , 1992, Science.

[15]  D. Selkoe,et al.  Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids , 1992, Nature.

[16]  D. Selkoe,et al.  Amyloid β-peptide is produced by cultured cells during normal metabolism , 1992, Nature.

[17]  Thomas Wisniewski,et al.  Apolipoprotein E: A pathological chaperone protein in patients with cerebral and systemic amyloid , 1992, Neuroscience Letters.

[18]  D. Price,et al.  Developmental expression of α1-antichymotrypsin in brain may be related to astrogliosis , 1991, Neurobiology of Aging.

[19]  P. Eikelenboom,et al.  Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin. , 1991, Acta neuropathologica.

[20]  E. Otomo,et al.  Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jakob disease , 1991, Brain Research.

[21]  H. Potter,et al.  α 1-Antichymotrypsin is associated solely with amyloid deposits containing the β-protein. Amyloid and cell localization of α 1-antichymotrypsin , 1990, Neurobiology of Aging.

[22]  M. Picken,et al.  Distribution of the Protease Inhibitor α1Antichymotrypsin in Cerebral and Systemic Amyloid , 1990 .

[23]  D. Selkoe,et al.  Immunochemical identification of the serine protease inhibitor α 1-antichymotrypsin in the brain amyloid deposits of Alzheimer's disease , 1988, Cell.

[24]  D. Selkoe,et al.  Synthetic peptide homologous to beta protein from Alzheimer disease forms amyloid-like fibrils in vitro. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[25]  J. Ghiso,et al.  In vitro formation of amyloid fibrils from two synthetic peptides of different lengths homologous to Alzheimer's disease β-protein , 1986 .

[26]  R. Gregg,et al.  Abnormal in vivo metabolism of apolipoprotein E4 in humans. , 1986, The Journal of clinical investigation.

[27]  K. Iqbal Alzheimer's disease : basic mechanisms, diagnosis and therapeutic strategies , 1991 .

[28]  S. Younkin,et al.  Astrocytes in Alzheimer's disease gray matter express alpha 1-antichymotrypsin mRNA. , 1989, The American journal of pathology.