Clinical utility of chromogranin A in SDHx‐related paragangliomas

Measurement of plasma/urinary catecholamine metabolites – especially normetanephrine (NMN) – represents a gold standard in biochemical detection of succinate dehydrogenase subunit B (SDHB) and D (SDHD)‐related pheochromocytomas (PHEO) and paragangliomas (PGL). This study was designed to assess diagnostic utility of chromogranin A (CgA) alone or in combination with NMN in patients with PHEO/PGL related to mutations in SDHB and SDHD.

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