Molecular cloning of cDNA and tissue‐specific expression of the gene for SII‐K1, a novel transcription elongation factor SII

Transcription elongation factor SII has been shown to promote read‐through by RNA polymerase II of pausing sites within various eukaryotic genes in vitro by inducing cleavage of the 3′‐end of the nascent transcript in the ternary elongation complex. Recently, we showed that various mouse tissues contain multiple SII‐related proteins. Of these, ‘general SII’ was ubiquitously expressed, whereas the others were expressed in a tissue‐specific manner. We have identified testis‐specific SII (SII‐T1) and shown that it was expressed exclusively in spermatocytes.

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